|   |
43 | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Y | E | M | A | Y | S | Q | Q | E | N | A | L | W | L | A | T | S | Q | S | R | K | L | D | K | G | G | V | V | Y | R | . |
. |
. |
. |
. |
. |
. |
L | D | P | V | T | L | E | V | T | Q | A | I | H | N | D | . |
. |
. |
. |
. |
. |
L | K | P | F | G | A | T | I | N | N | T | T | Q | T | L | W | F | G | N | T | V |
Query Conservation |   |
  |   |   |   |
|   |
|
|
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
| . | . | . | . | . | . | . |
|
|   |   |
|   |   |
|   |   |   |
|   |   |
| . | . | . | . | . | . |   |   |
|   |   |
|
|   |   |   |
|
|   |   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |   |   |   |   |
|   |
|   |
|
|
|   |
|
|   |   |   |
|
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |
|
|   |   |   |
|
|
|
|
|
|
|
|   |
Template Sequence |   |
S | T | A | F | A | Y | D | A | E | G | E | K | L | F | L | A | V | P | R | K | L | P | R | V | P | Y | T | L | A | E | V | D | T | K | N | S | L | G | V | K | G | K | H | S | P | L | L | N | K | F | S | G | H | K | T | G | K | E | L | T | S | I | Y | Q | P | V | I | D | D | C | R | R | L | W | V | V | D | I | G | S |
Template Known Secondary structure |   |
|
|  |  |  |  |  | T | T | T | T |  |  |  |  |  |
|
| T | T | S | T | T |
| S |
| S |  |  |  |  |  |  |  |  |  | T | T |
| T | T |
| S | S |
|
| B |  |  |
| T | T |
| S | S | S |
| S | S | S |
|  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |
| S | S |
Template Predicted Secondary structure |   |
 |  |
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
28 | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . |
  |
  |   |
110 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 120 | . | . | . | |
|
. | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | |
|
|
|
. | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|  |  | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | V | T | A | I | D | A | K | T | G | E | V | . |
. |
K | G | R | L | V | L | D | D | R | K | R | T | E | E | V | R | P | L | Q | P | R | E | L | V | A | D | D | A | T | N | . |
. |
. |
. |
T | V | Y | I | S | G | I | G | K | E | S | V | I | W | V | V |
Query Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   |   |   |   |   | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|
|   |
|
|   |
|   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|
|   |   |   |   | . |
|
|
|
|
|
Template Sequence |   |
V | E | Y | R | S | R | G | A | K | D | Y | P | S | H | R | P | A | I | V | A | Y | D | L | K | Q | P | N | Y | P | E | V | V | R | Y | Y | F | P | T | R | L | V | E | K | P | T | Y | F | G | G | F | A | V | D | V | A | N | P | K | G | D | C | S | E | T | F | V | Y | I | T | N | F | L | R | G | . |
A | L | F | I | Y |
Template Known Secondary structure |   |
| S | S |
| S | T | T | G | G | G | S |
|
|
|
|
|  |  |  |  |  |  | S | S | S | T | T |
|
|  |  |  |  |  |  |
|
| G | G | G |
|
|
| G | G | G |  |  |  |  |  |  |  |  | S |
| T | T | T | T | S |
| S |  |  |  |  |  |  |  | T | T | T | T | . |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
108 | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | |
. | . | . | . | . |
  |
  |   |
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
|
|
|
. | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
Query Sequence |   |
D | G | G | N | I | K | L | K | T | A | I | Q | N | T | G | K | M | S | T | G | L | A | L | D | S | E | G | K | R | L | Y | T | T | N | A | D | G | E | L | I | T | I | D | T | A | D | N | K | I | L | S | R | K | K | L | L | D | D | G | K | E | H | F | F | I | N | I | S | L | D | T | A | R | . |
. |
. |
. |
Q | R | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
Template Conservation |   |
|   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|
|
|
|
|
|   |   |   |   |   |   |
|   |
|
Template Sequence |   |
D | H | K | K | Q | D | S | W | N | V | T | H | P | T | F | K | A | E | R | P | T | K | F | D | Y | G | G | K | E | Y | E | F | K | A | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | F | G | I | T | L | G | D | R | D | S | E | G | N | R | P | A |
Template Known Secondary structure |   |
 | T | T | T | T |  |  |  |  |  |  |
| G | G | G | S |
|
| S |
|  |  |  |  |  | T | T |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
| T | T | S |
|
|  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
187 | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
  |
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
F | I | T | D | S | K | A | A | E | V | L | V | V | D | T | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | G | N | I | L | A | K | V | A | A | P | E | S | L | A | V | L | F | N | P | A | R | N | E | A | Y | V | T | H | R | Q | A | G | K | V | S | V | I | D | A | K | S | Y | . |
. |
. |
. |
. |
. |
. |
K | V | V | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   | . | . | . | . | . | . | . |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
|
|   |   |
|
|
|   |   |
|
|   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
Y | Y | L | A | G | S | A | I | K | V | Y | S | V | N | T | K | E | L | K | Q | K | G | G | K | L | N | P | E | L | L | G | N | R | G | K | Y | N | D | A | I | A | L | A | Y | D | P | K | T | K | V | I | F | F | A | E | A | N | T | K | Q | V | S | C | W | N | T | Q | K | M | P | L | R | M | K | N | T | D | V | V | Y |
Template Known Secondary structure |   |
 |  |  |  | S | S |
| S |  |  |  |  |  |  |  |  |  |  | S | S | T | T |
|
|
|
|
|  |  |  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |
| T | T | T |
|  |  |  |  |  |  | S | S | S | S |  |  |  |  |  |  | T | T | S |
| S | B |
| G | G | G |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
  |
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | F | D | T | P | T | H | P | N | S | L | A | L | S | A | D | G | K | T | L | Y | V | S | V | K |
Query Conservation |   |
  |
|   |   |
|   |   |
|   |   |
|
|   |
|
|
|
|   |   |
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |
|   |
|
|
|   |
|
|
|
Template Sequence |   |
T | S | S | R | F | V | F | G | T | D | I | S | V | D | S | K | G | G | L | W | F | M | S | N | G |
Template Known Secondary structure |   |
 |
| T | T |
|
| S |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |
| S |
Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . |
  |