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Job DescriptionP76116
Confidence98.91%DateWed Jan 25 15:21:05 GMT 2012
Rank146Aligned Residues301
% Identity9%Templatec2qtbB_
PDB info PDB header:hydrolaseChain: B: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor
Resolution2.25 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   38.40.........50.........60........ .70.........80.........90.........100.........110.....
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Query Sequence  AVGKGAYEMAYSQQENALWLATSQSRKLDKG. . GVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQTLWFGNTVNSAVTA
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Template Sequence  EFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVW. . NNDIYV
Template Known Secondary structure  TSSS



TTSS
SSS
TTTT

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SSB

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   97..100.........110.........120.........130.........140.........150.........160........ .170....
 
   116...120.........130.........140... ......150.........160....
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Query Sequence  IDAKTGEVKGRLVLDDRKRTEEVRPLQP. . . . . . . . . RELVADDATNTVYISGIGKES. . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  KIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRV
Template Known Secondary structure  SSTTS



S

BTTTSB

TTSSSB

TTSS
TT



STT
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   175....180.........190.........200.........210.........220.........230.........240.........250....
 
   165....170.... .....180.........190.........200........
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Query Sequence  . . . . . . . . . . . . VIWVVDGGNI. . . . . . . . . . . . . . . . . . . . . . . . KLKTAIQNTGKMSTGLALDSEGKRLYTTNADGEL
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Template Conservation   
   
  
    
 
 
                                

 

   
    
                
Template Sequence  PYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESS
Template Known Secondary structure 

BTTS


GGGTTTSSS






TS
TTSSTTTTT
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   255....260.........270.........280.........290.........300.........310.........320.........330....
 
   209210.........220.........230.........240.........250 .........260.........270.........280.....
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Query Sequence  ITIDTADNKILSRKKLLDDGKEHFFINISLDTARQRAFITDS. . . KAAEVLVVDTRNGNILAKVAAPESLAVLFNPARNE
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Template Conservation                                  
        
                    

     
          
Template Sequence  GRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDY
Template Known Secondary structure  T
GGG

SSS
SSSSS




TTSS
TTS
TT
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   335....340.........350.........360.........370.........380.........390.........400.........410....
 
   286...290..... ....300.........310....... ..320.........330.........340
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Query Sequence  AYVTHRQAGK. . . . . . VSVIDAKSYKVVKTFDTPTHPN. . . . . SLALSADGKTLYVSVKQKSTKQQ
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Template Sequence  LYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLY
Template Known Secondary structure  S
GGG
TT
BTTSSTTTSTTTB
B
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   415....420.........430.........440.........450.........460.........470.........480
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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