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Job DescriptionP76116
Confidence99.03%DateWed Jan 25 15:21:05 GMT 2012
Rank140Aligned Residues298
% Identity7%Templatec2g5tA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   38.40.........50........ .60.........70.........80.........90.........100.........110.....
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Query Sequence  AVGKGAYEMAYSQQENALWLA. . TSQSRKLDKGGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQTLWFGNTVNSAVTA
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Template Sequence  EFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVW. . NNDIYV
Template Known Secondary structure  GGSS


B
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SSS
TTTT

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SSB

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   97..100.........110.........120.........130.........140.........150.........160........ .170....
 
   116...120.........130... ......140.........150...
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Query Sequence  IDAKTGEVKGRLVLDDRK. . . . . . . . . . . . . . . . . . . RTEEVRPLQPRELVADDATN. . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  KIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRV
Template Known Secondary structure  SSTTS



S

BTTTSB

TSSSSB

TTSS
TT



STT
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   175....180.........190.........200.........210.........220.........230.........240.........250....
 
   154.....160.........170.........180.........190.........200. .......
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Query Sequence  . . . . . . . . . . . . TVYISGIGKESVIWVVDGGNIKLKTAIQNTGKMSTGLALDSEGKRLYT. . . . . . . . . . . . . TNADGEL
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Template Conservation   
   
  
    
 
 
                                

 
         
                
Template Sequence  PYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESS
Template Known Secondary structure 

BTTS


TTS

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TS

SSSSSTTGGG
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   255....260.........270.........280.........290.........300.........310.........320.........330....
 
   209210.........220.........230.........240.........250.... .....260.........270.........280.....
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Query Sequence  ITIDTADNKILSRKKLLDDGKEHFFINISLDTARQRAFITDSKAAE. . . VLVVDTRNGNILAKVAAPESLAVLFNPARNE
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Template Conservation                                  
                
            

 
   
          
Template Sequence  GRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDY
Template Known Secondary structure  T

TTS

SSS
SSSSS




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   335....340.........350.........360.........370.........380.........390.........400.........410....
 
   286...290..... ....300.........310...... ...320.........330.......
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Query Sequence  AYVTHRQAGK. . . . . . VSVIDAKSYKVVKTFDTPTHP. . . . . NSLALSADGKTLYVSVKQKST
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Template Conservation                  
  
          

         
   
 
 

            
Template Sequence  LYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGL
Template Known Secondary structure  S
GGG
TT
BTT
TT
SSTTT
TTTB
B
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   415....420.........430.........440.........450.........460.........470.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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