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Job DescriptionP00956
Confidence100.00%DateThu Jan 5 10:57:19 GMT 2012
Rank1Aligned Residues904
% Identity43%Templatec1qu2A_
PDB info PDB header:ligase/rnaChain: A: PDB Molecule:isoleucyl-trna synthetase; PDBTitle: insights into editing from an ile-trna synthetase structure2 with trna(ile) and mupirocin
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3......10.........20.........30.........40.........50.........60.........70.........80..
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Query Sequence  DYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSK
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Template Sequence  DYEKTLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYK
Template Known Secondary structure 
SGGGS







SS

TTTTTS
B





BSSS


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   2.......10.........20.........30.........40.........50.........60.........70.........80.
 
   83......90.........100.........110.........120.........130.........140.........150.........160..
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Query Sequence  GLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTE
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Template Sequence  TMQGFYAPYVPGWDTHGLPIEQALTKKGVDR. KKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYE
Template Known Secondary structure  TTT
B




B

ST

S.TTT
TTT

S
TTS
TTS
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   82.......90.........100.........110.. .......120.........130.........140.........150.........160
 
   163......170.........180.........190.........200.........210.........220.........230.........240..
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Query Sequence  ANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVDQDALKAKFAVSNVNGPISLVIWTT
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Template Sequence  AAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFNVKDDKGVVD. . . . . . . . ADAKFIIWTT
Template Known Secondary structure  TT
TTTT

GGG

B


SSTTGGG........TT

B

S
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   161........170.........180.........190.........200.........210.........220.. .......230..
 
   243......250.........260.........270.........280........ .290.........300.........310.........320
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Query Sequence  TPWTLPANRAISIAPDFDYALVQIDGQAVILAKDLVESVMQRIGVT. . DYTILGTVKGAELELLRFTHPFMGFDVPAILG
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Template Sequence  TPWTIPSNVAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEWVVAQHPFLDRESLVING
Template Known Secondary structure 
GGGSS

B




TT






TTTT




TTTT

SS








TTT
TT


B

TT

SB




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   233......240.........250.........260.........270.........280.........290.........300.........310..
 
   321........330.........340.........350.........360.........370.........380.........390.........400
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Query Sequence  DHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQ
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Template Sequence  DHVTTDAGTGCVHTAPGHGEDDYIVGQQYELPVISPIDDKGVFTEE. GGQFEGMFYDKANKAVTDLLTEKGALLKLDFIT
Template Known Secondary structure 
SS

SSS
S


B
TTS
STTTSSS







SSS


TT.
SS
SSS
SSTTGGGSS



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   313......320.........330.........340.........350........ .360.........370.........380.........390.
 
   401........410.........420.........430.........440.........450.........460.........470.........480
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Query Sequence  HSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHK
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Template Sequence  HSYPHDWRTKKPVIFRATPQWFASISK. . VRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAE
Template Known Secondary structure  TTT

B

..TSSS



S
SSS
B



T
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   392.......400.........410........ .420.........430.........440.........450.........460.........
 
   481........490.........500.........510....... ..520.........530.........540.........550...
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Query Sequence  DTEELHPRTLELMEEVAKRVEVDGIQAWWDLDAKEIL. . . . . . . GDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAG
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Template Sequence  NGE. . IIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETR. PELS
Template Known Secondary structure  TS
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TS
SSTT


SS
TTS





TTTTTS.TT

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   470.. .......480.........490.........500.........510.........520.........530.........540.. ....
 
   554.....560.........570.........580.........590.........600.........610.........620.........630...
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Query Sequence  HAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTD
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Template Sequence  FPADMYLEGSDQYRGWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTD
Template Known Secondary structure  SSBSGGGGTTSS
SBS


TTS



SSSS



T
TS
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   547..550.........560.........570.........580.........590.........600.........610.........620......
 
   634.....640.........650.........660.........670.........680.........690.........700.........710...
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Query Sequence  YTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILKAYEAYDFHEVVQ
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Template Conservation     
   
   
        

 
  
  
  
                  
  

  
   
  
    
   
  
  
Template Sequence  YLADVRISDEILKQTSDDYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQ
Template Known Secondary structure  TTS


TSTT




GGGS
TT
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   627..630.........640.........650.........660.........670.........680.........690.........700......
 
   714.....720.........730.........740.........750.........760.........770.........780.........790...
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Query Sequence  RLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYE
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Template Sequence  EVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPK
Template Known Secondary structure 





TTS
TT
TTTSTTSTT
SSSSGGGS



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   707..710.........720.........730.........740.........750.........760.........770.........780......
 
   794.....800.........810.........820.........830.........840....... ..850.........860.........870..
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Query Sequence  GLFGLADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPE. LSAKLTALGDELRFVLLTSGATVAD
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Template Sequence  VVE. . VDQAL. . LDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVD
Template Known Secondary structure 


..

..TTS
SSGGG

SS

GGG
S
TTSS
S
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   787.. 790.... .....800.........810.........820.........830.........840.........850.........860..
 
   873......880.........890.........900.........910.........920.........930
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Query Sequence  YNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKVAEHAEICGRCVSNVAG
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Template Sequence  KLDDQAT. . . . . AYEHGDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKS
Template Known Secondary structure 


TTS.....TT
SS
TTT

S

TT
T
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   863...... 870.........880.........890.........900.........910.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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