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Job DescriptionP00956
Confidence100.00%DateThu Jan 5 10:57:19 GMT 2012
Rank6Aligned Residues678
% Identity21%Templatec1obhA_
PDB info PDB header:synthetaseChain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: leucyl-trna synthetase from thermus thermophilus complexed2 with a pre-transfer editing substrate analogue in both3 synthetic active site and editing site
Resolution2.2 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   18.20.........30.........40.........50.........60.........70.........80.........90.......
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Query Sequence  RGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDC
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Template Sequence  KYNPHAIEAKWQRFWEEKGFMKA. . KDLPGGGKQYVLVMFPYPSGDLHMGHLKNYTMGDVLARFRRMQGYEVLHPMGWDA
Template Known Secondary structure 



TTTTT

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SS
BT




B

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   3......10.........20..... ....30.........40.........50.........60.........70.........80
 
   98.100.........110.........120.........130.........140.........150.........160.........170.......
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Query Sequence  HGLPIELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGH
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Template Sequence  FGLPAENAALKFGVHP. . . . . . . . . . . . . KDWTYANIRQAKESLRLMGILYDWDREVTTCEPEYYRWNQWIFLKMWEKGL
Template Known Secondary structure 
S


.............TT



GGG

BTTSTT
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   82.......90....... ..100.........110.........120.........130.........140........
 
   178.180.........190.........200....... ..210.........220.........230.........240....
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Query Sequence  LHKGAKPVHWCVDCRSALAEAEVEYYDKTS. . . . . . . . . . . . . PSIDVAFQAVDQDALKAKFAVSNVNGPISLVIWTTTP
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Template Sequence  AYRAKEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGRSEGAEILFPVEGK. . . . . . . . . . . . . . EVRIPVFTTRP
Template Known Secondary structure 


GGGGTTTT

S

BTT
..............S
S
G
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   149150.........160.........170.........180.........190.........200... ......210....
 
   245....250.........260.........270.........280.........290.........300.........310.........320....
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Query Sequence  WTLPANRAISIAPDFDYALVQIDGQAVILAKDLVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVT
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Template Sequence  DTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEI. ERQAEGREKTGVFLGAYALNPATGERIPIWTADYVL
Template Known Secondary structure  GGGGG


TT
TTTTTS

GGGTS
.S
TTS



TTT

TTS
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   251........260.........270.........280.........290... ......300.........310.........320.........
 
   325....330.........340.........350.........360.........370.........380.........390.........400....
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Query Sequence  LDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYP
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Template Sequence  FGYGTGAIMAVPAHDQRDYEFARKFGLPIKKVIERPGEPLPEPLE. . . . . . . . . . . . . . . RAYEEPGIMVNSGPFDGTES
Template Known Secondary structure  SSSTTS
GGG
T





BTTB


SS
S...............S


S


SSGGGTT
B
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   330.........340.........350.........360.........370.... .....380.........390....
 
   405....410.........420.........430.........440.........450.........460.........470.........480....
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Query Sequence  CCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKDTEE
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Template Sequence  EE. . . . . . . . . . . . . . . . . . . . . . . GKRKVIAWLEEKGLGK. . . . . . . GRVTYRLRDWLISRQRYWGTPIPMVHCV. . . .
Template Known Secondary structure  .......................TS.......S





SSS




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   395. ...400.........410.. .......420.........430.........440
 
   485....490.........500.........510.........520.........530.........540........ .550.....
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Query Sequence  LHPRTLELMEEVAKRVEVDGIQAWWDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVR. . . . . . . . . PEFAGHA
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Template Sequence  VPVPEEELPVLLPDLKDVEDISPLEAHPEF. . . . YETTCPKRDTDTMDTFFDSSWYYLRYTDPHNDRLPFDPEKANAWMP
Template Known Secondary structure 

GGG







S
STT

GGGG
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B



TTTTSTT
SSSS


S
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   445....450.........460.........470.... .....480.........490.........500.........510.........520
 
   556...560..... ....570.........580.........590........
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Query Sequence  ADMYLEGSDQ. . . . . . HRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  VDQYIGGVEHAVLHLLYSRFFTKFLHDLGMVKVEEPFQGLFTQGMVLAWTDFGPVEVEGSVVRLPEPTRIRLEIPESALS
Template Known Secondary structure  BS

TT
TTS
S
S
SBS



TT

T
S
S
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   532.......540.........550.........560.........570.........580.........590.........600.........610.
 
   599600.........610.........620.........630 .........640.........650.....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . QGRKMSKSIGNTVSPQDVMNKLGADILRLWVA. STDYTGEMAVSDEILKRAADSYRRI
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Template Sequence  LEDVRKMGAELRPHEDGTLHLWKPAVMSKSKGNGVMVGPFVKEQGADIARITILFAAPPENEMVWTEEGVQGAWRFLNRI
Template Known Secondary structure  TT

TTSS

TTTT


BS
S
TTS

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   612.......620.........630.........640.........650.........660.........670.........680.........690.
 
   656...660.........670.........680.........690.........700.........710.........720.........730.....
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Query Sequence  RNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQ
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Template Sequence  YRRVAEDREALLET. . . SGVFQAEALEGKDRELYGKLHETLKKVTEDLEALRFNTAIAALMEFL. . . . . NALYEYRKDRP
Template Known Secondary structure  TT
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GGG

TT
.....S
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   692.......700..... ....710.........720.........730.........740.........750.. .......760...
 
   736...740.........750.........760.........770.........780.........790.........800.
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Query Sequence  YTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGLADS
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Template Sequence  VT. . . . . . . . . . . . PVYRTAIRYYLQMLFPFAPHLAEELWHWFW. . . PDSLFEAGWPELDEKALEK
Template Known Secondary structure  S
............TTTSTTT
...SS






TGGG

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   764. ....770.........780.........790..... ....800.........810....
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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