|   |
41 | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | W | I | L | M | D | Y | A | S | G | K | V | L | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | G | N | A | D | E | K | L | D | P | A | S | L | T | K | I | M | T | S | Y | V | V | G | Q | A | L | K | A | D | K | I | K | L | T |
Query Conservation |   |
  |
|
|
|   |
|   |   |
|
|   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |   |   |   |
|   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|   |   |
|
|   |
|
|
|   |   |
|   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   |
|
|
|
| . | . | . |   |
|   |   |   |   |   |
Template Sequence |   |
S | G | T | A | I | H | P | Q | T | G | E | L | L | A | L | V | S | T | P | S | Y | D | V | Y | P | F | M | Y | G | M | S | N | E | E | Y | N | K | L | T | E | D | K | K | E | P | L | L | N | K | F | Q | I | T | T | S | P | G | S | T | Q | K | I | L | T | A | M | I | G | L | N | . |
. |
. |
N | K | T | L | D | D | K |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  | S |
|
|
| S |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | T |
| T | T |
| T | T | S |
| T | T | T | S |
| B |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  | . | . | . | T | T | S | S |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
346 | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | |
|
|
. | . | . | . | 420 | . | . |
  |
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | M | V | T | V | G | K | D | A | W | A | T | G | N | P | A | L | R | G | S | S | V | M | F | L | K | P | G | D | Q | V | S | V | A | D | L | N | K | G | V | I | I | Q | S | G | N | D | A | C | I | A | L | A | D | Y | V | A | G | S | Q | E | S | F | I | G | L | M | N | G | Y | A | K | K | L | G | L | T | N | T | T |
Query Conservation |   |
  |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|
|
|   |   |   |
|
|   |
|   |
|
|
|
|   |
|
|
|   |   |
|
|
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |
|
|
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   | . | . | . | . |
|
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |
|
| . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
Template Sequence |   |
T | S | Y | K | I | D | G | K | G | W | Q | K | D | K | S | W | G | G | Y | N | V | T | R | Y | E | V | V | N | G | N | I | D | L | K | Q | . |
. |
. |
. |
A | I | E | S | S | D | N | I | F | F | A | R | V | A | L | E | L | G | . |
. |
. |
. |
. |
. |
S | K | K | F | E | K | G | M | K | K | L | G | V | G | E | D | I |
Template Known Secondary structure |   |
|  |  |  |  |
| S | S |  |  |
| S | S | G | G | G | T | T |
|
|  |  |
| S | S |
|
|
|  |  |  |  |  |  |  | . | . | . | . |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T | T | T | S |
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
423 | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | |
|
|
|
. | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . |
  |
  |   |
169 | 170 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | Q | T | V | H | G | L | D | A | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Q | F | S | T | A | R | D | M | A | L | L | G | K | A | L | I | H | D | . |
. |
. |
. |
V | P | E | E | Y | A | I | H | K | E | K | E | F | T | F | N | K | I | R | Q | P | N | R | N | R | L | L |
Query Conservation |   |
|   |
|
|   |
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   | . | . | . | . |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
P | S | D | Y | P | F | Y | N | A | Q | I | S | N | K | N | L | D | N | E | I | L | L | A | D | S | G | Y | G | Q | G | E | I | L | I | N | P | V | Q | I | L | S | I | Y | S | A | L | E | N | N | G | N | I | N | A | P | H | L | L | K | D | T | K | N | K | V | W | K | K | N | I | I | S | K | E | N | I | N | L | L | T |
Template Known Secondary structure |   |
|
| S | S |
|
|
|
|
| B | S |
| S | S |
|
|
| S |  |  |  |  |  |  |  |  | T | T |
| S | S |
| B | B |
|  |  |  |  |  |  |  |  |  | G | G | G | T | T | T |
|  |  |
|
| B |
|
| T | T | S |
|
|
|  |  |  |
|
|
| S |
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
493 | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | |
|
|
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | S | S | N | L | N | V | D | G | M | K | T | G | T | T | A | G | A | G | Y | . |
. |
. |
N | L | V | A | S | A | T | Q | G | D | M | R | L | I | S | V | V | L | G | A | K | T | D | R | I | R | F | N | E | S | E | K | L | L | T | W | G | F | R | F | F |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |   |
|
|   | . | . | . |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
Template Sequence |   |
D | G | M | Q | Q | V | V | N | K | T | H | K | E | D | I | Y | R | S | Y | A | N | L | I | G | K | S | G | T | A | E | L | K | G | R | Q | I | G | W | F | I | S | Y | D | K | D | N | P | N | M | M | M | A | I | N | V | K | D | V | Q | D | K | G | M | A | S | Y | N | A | K | I | S | G | K | V | Y | D | E | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T | T | T | T | T | T |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | T | T | S |
| S |
|  |  |  |  |  |  |  |
|
| T | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
573 | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 |
  |