|   |
41 | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | W | I | L | M | D | Y | A | S | G | K | V | L | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | G | N | A | D | E | K | L | D | P | A | S | L | T | K | I | M | T | S | Y | V | V | G | Q | A | L | K | A | D | K |
Query Conservation |   |
  |
|
|
|   |
|   |   |
|
|   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
Template Conservation |   |
|   |
|
|   |
|   |   |
|
|   |
|
|
|
|
|
|   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|
|
|
|
|   | . | . | . |
|   |
Template Sequence |   |
A | V | V | A | L | E | P | S | T | G | K | I | L | A | L | V | S | S | P | S | Y | D | P | N | L | L | A | S | H | N | P | E | V | Q | A | Q | A | W | Q | R | L | G | D | N | P | A | S | P | L | T | N | R | A | I | S | E | T | Y | P | P | G | S | T | F | K | V | I | T | T | A | A | A | L | A | A | . |
. |
. |
G | A |
Template Known Secondary structure |   |
 |  |  |  |  |
| T | T | T |
| B |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
| T | T | S |
| T | T | T | S |
|
| B |
|
| G | G | G | G |  |  |  |  |  |  |  |  |  |  | T | . | . | . | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | |
|
|
. | . |
  |
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | K | L | T | D | M | V | T | V | G | K | D | A | W | A | T | G | N | P | A | L | R | G | S | S | V | M | F | L | K | P | G | D | Q | V | S | V | A | D | L | N | K | G | V | I | I | Q | S | G | N | D | A | C | I | A | L | A | D | Y | V | A | G | S | Q | E | S | F | I | G | L | M | N | G | Y | A | K | K | L | G | L |
Query Conservation |   |
  |   |
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|
|
|   |   |   |
|
|   |
|   |
|
|
|
|   |
|
|
|   |   |
|
|
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|
|
| . | . | . | . |   |   |
|
|   |   |
|   |
|   |   |
|   |   |
|   |   |   |
|
| . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
T | E | T | E | Q | L | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | A | P | T | I | P | L | E | N | Y | P | C | G | D | E | P | T | V | S | L | . |
. |
. |
. |
R | E | A | F | V | K | S | C | N | T | A | F | V | Q | L | G | I | R | T | G | . |
. |
. |
. |
. |
. |
A | D | A | L | R | S | M | A | R | A | F | G | L |
Template Known Secondary structure |   |
| T | T |
|  |  |  | . | . | . | . | . | . | . | . | . | . |
|
| S | B |
|
|
| B |
|
|
|
| S | S | S | S |  |  |  |  | . | . | . | . |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
238 | . | 240 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | |
|
|
|
. | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 290 | . | . | . | . | . | . | . |
  |
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | N | T | T | F | Q | T | V | H | G | L | D | A | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Q | F | S | T | A | R | D | M | A | L | L | G | K | A | L | I | H | D | V | P | E | E | Y | A | I | H | K | E | K | E | F | T | F | N | K | I | R | Q | P | N | R | N | R | L |
Query Conservation |   |
  |   |
|   |
|   |
|
|   |
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
Alig confidence |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |   |
|
|
|
|
|
| . |
|   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
D | S | P | . |
. |
P | R | P | T | P | L | Q | V | A | E | S | T | V | G | P | I | P | D | S | A | A | L | G | M | T | S | I | G | Q | K | D | V | A | L | T | P | L | A | N | A | E | I | A | A | T | I | A | N | G | . |
G | I | T | M | R | P | Y | L | V | G | S | L | K | G | P | D | L | A | N | I | S | T | T | V | G |
Template Known Secondary structure |   |
T | S |
| . | . |
|
|
| S | S | S |
|
|
|
|
| B |
|
|
|
|
| S |  |  |  |  |  |  |  | T | T | T |
| T | T |
| B | B |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | T |  |  |  |
|
| B | S |  |  |  |  |  |
| T | T |
|
|  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
308 | . | 310 | |
|
. | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | |
360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . |
  |
  |   |
224 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
Predicted Secondary structure |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | S | S | N | L | N | V | D | G | M | K | T | G | T | T | A | G | A | G | Y | . |
. |
. |
. |
. |
. |
. |
. |
N | L | V | A | S | A | T | Q | G | D | M | R | L | I | S | V | V | L |
Query Conservation |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |   |
|
|   | . | . | . | . | . | . | . | . |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |
|
|
|
Alig confidence |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |   |   |
|   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |   |
|   |   |
|
|   |
|   |
Template Sequence |   |
Y | Q | Q | R | R | A | V | S | P | Q | V | A | A | K | L | T | E | L | M | V | G | A | E | K | V | A | Q | Q | K | G | A | I | P | G | V | Q | I | A | S | K | T | G | T | A | E | H | G | T | D | P | R | H | T | P | P | H | A | W | Y | I | A | F | A | P | A | Q | A | P | K | V | A | V | A | V | L |
Template Known Secondary structure |   |
|  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| T | T |
|
| T | T |
|
|
|  |  |  |  |  |  |  |
|
| S | S |
| T | T | T | S |
|
|  |  |  |  |  |  |  |  | S | T | T | S |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
385 | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . |
  |