Return to main results Retrieve Phyre Job Id

Job DescriptionP25516
Confidence100.00%DateThu Jan 5 11:41:52 GMT 2012
Rank1Aligned Residues878
% Identity52%Templatec2b3yB_
PDB info PDB header:lyaseChain: B: PDB Molecule:iron-responsive element binding protein 1; PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1)
Resolution1.85 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3......10.........20.........30.........40.........50.........60.........70.........80..
Predicted Secondary structure 


































Query SS confidence 















































































Query Sequence  STLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSLKVLLENLLRWQDGNSVTEEDIHALAGWLKNAHADREIAYR
Query Conservation            
           
            

 
 


 
   
                          

   
Alig confidence 



























..

















































Template Conservation    
       
           
     ..     

   


 
   
                          

   
Template Sequence  SNPFAHLAEPLDPVQPGKKFFNLNKLED. . SRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIENILHWNVTQHKNIEVPFK
Template Known Secondary structure 

TTGGGS
TTSTT

GGGG

..TTGGGS
T

SSSS
TTTTT

Template Predicted Secondary structure 











..


























Template SS confidence 















































































   2.......10.........20......... 30.........40.........50.........60.........70.........
 
   83......90.........100.........110.........120.........130.........140.........150.........160..
Predicted Secondary structure 




















Query SS confidence 















































































Query Sequence  PARVLMQDFTGVPAVVDLAAMREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFLKW
Query Conservation 
 


 

 

  
  

 


      
 
   
 
  

 






  
      
   
   
  

 

  



Alig confidence 















































































Template Conservation 
 

  

 

  
  
  


      
 

  
 
  
  

 



  
      
   
   
  

 

  


 
Template Sequence  PARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPADLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKW
Template Known Secondary structure 
STT

GGG
S
SS


SS


SS
SSTT
Template Predicted Secondary structure 





















Template SS confidence 















































































   80.........90.........100.........110.........120.........130.........140.........150.........
 
   163......170.........180.........190.........200.........210.........220.........230.........240..
Predicted Secondary structure 







































Query SS confidence 















































































Query Sequence  GKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMINGLGVLGWGVGGIEAEAAMLGQPV
Query Conservation           
 


 

 


 

 
  

          
 










   



 

 






   
 
   
Alig confidence 
































....










































Template Conservation           
 


 

 


 

 

 

  
.... 
   










   






 



 

  



   
Template Sequence  GSQAFHNMRIIPPGSGIIHQVNLEYLARVVFDQ. . . . DGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPI
Template Known Secondary structure  STT
TTS

TT

S....TT
SSGGGGGGGGGT


TT

Template Predicted Secondary structure 










....




















Template SS confidence 















































































   160.........170.........180.........190.. .......200.........210.........220.........230.....
 
   243......250.........260.........270.........280.........290.........300.........310.........320..
Predicted Secondary structure 




















Query SS confidence 















































































Query Sequence  SMLIPDVVGFKLTGKLREGITATDLVLTVTQMLRKHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAV
Query Conservation     




 
 


 
  








 
   
   
 


 


 
 

  

   
 





 
 


 



 

 
Alig confidence 















































































Template Conservation     




 
 


 
  








 
   
   
 


 


 
 

  


  
 





 
 


 



 

 
Template Sequence  SMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEYGATAAFFPVDEV
Template Known Secondary structure 


S


TT



TT
STTTTTS
TT
S



Template Predicted Secondary structure 






















Template SS confidence 















































































   236...240.........250.........260.........270.........280.........290.........300.........310.....
 
   323......330.........340.........350.. .......360.........370.........380.........390.........
Predicted Secondary structure 






...





























Query SS confidence 





























. . .














































Query Sequence  TLDYMRLSGRSEDQVELVEKYAKAQGMWRN. . . PGDEPIFTSTLELDMNDVEASLAGPKRPQDRVALPDVPKAFAASNEL
Query Conservation 
  

  


            
   
   ... 
 

 
   





 


 

 
  
 
 
 



          
Alig confidence 





























...














































Template Conservation 
  

  


        
 
 
   
       
 

 
   





 


 

 
  
   
 



          
Template Sequence  SITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGA
Template Known Secondary structure  TT

T



TT
GGG



SGGG



SS
TT
GGGS
Template Predicted Secondary structure 





























Template SS confidence 















































































   316...320.........330.........340.........350.........360.........370.........380.........390.....
 
   400.. .......410.........420.........430.........440.........450.........460.........470...
Predicted Secondary structure 


......










































Query SS confidence 


. . . . . .






































































Query Sequence  EVN. . . . . . ATHKDRQPVDYVMNGHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLLAKKAVTLGLKRQPWVKASLAPGS
Query Conservation     ......                        
  
 





   


  

 


  

  
 

   

  
 


Alig confidence 


......






































































Template Conservation                              
    
  
 





   


  

 


  

  
 

 
 

  
 


Template Sequence  KQGFKGFQVAPEHHNDHKTFIYDNTEFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGS
Template Known Secondary structure 
SBTTB



GGGTT
TTTTB

T
TT



TTS

SS
Template Predicted Secondary structure 




















































Template SS confidence 















































































   396...400.........410.........420.........430.........440.........450.........460.........470.....
 
   474.....480.........490.........500.........510.........520.........530.........540.........550...
Predicted Secondary structure 












































Query SS confidence 















































































Query Sequence  KVVSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNSGPLPDPIETAIKKSDLTVGAVLSGNRNFEGRIHPLVKTNWLASPP
Query Conservation    
   
   

   
  

  
   


 


  
 
    
  
       
 
 
 



 

 
      




 
Alig confidence 















































































Template Conservation    
   
   

   
  

  
   


 


    
    
  
       
 


 



 

 
      




 
Template Sequence  GVVTYYLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEGRVHPNTRANYLASPP
Template Known Secondary structure  TT
T

B

SS
GGGGT





T


SSS


TTSS
TT
S

Template Predicted Secondary structure 












































Template SS confidence 















































































   476...480.........490.........500.........510.........520.........530.........540.........550.....
 
   554.....560.........570.........580.........590.........600 .........610.........620.........630..
Predicted Secondary structure 























.





























Query SS confidence 














































.































Query Sequence  LVVAYALAGNMNINLASEPIGHDRKGDPVYLKDIWPSAQEIARAVEQ. VSTEMFRKEYAEVFEGTAEWKGINVTRSDTYG
Query Conservation   







 
  
   



    
  
 
 



   

      .         
            
         
Alig confidence 














































.































Template Conservation 



 



 
  
   



    
  
 
 



   

         
  
   
            
         
Template Sequence  LVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVERQYVIPGMFKEVYQKIETVNESWNALATPSDKLFF
Template Known Secondary structure 
BS


TTTS
STTT





TTTTT







SS

Template Predicted Secondary structure 











































Template SS confidence 















































































   556...560.........570.........580.........590.........600.........610.........620.........630.....
 
   633......640.........650.........660.........670.........680.........690.........700.........710..
Predicted Secondary structure 


























































Query SS confidence 















































































Query Sequence  WQEDSTYIRLSPFFDEMQATPAPVEDIHGARILAMLGDSVTTDHISPAGSIKPDSPAGRYLQGRGVERKDFNSYGSRRGN
Query Conservation 
   

 
  

 
                


   

 









 
   
 

  
   
    


 
  



Alig confidence 















































































Template Conservation 
   

 
  

 
                


   

 









 
   
 

 

   
    
 
 
  



Template Sequence  WNSKSTYIKSPPFFENLTLDLQPPKSIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGN
Template Known Secondary structure 

TT
SS



STTTT

SS







S

BS

S


SSSTT

GGG


TGGGTT
Template Predicted Secondary structure 

















































Template SS confidence 















































































   636...640.........650.........660.........670.........680.........690.........700.........710.....
 
   713......720.........730.........740.........750.........760.........770.........780.........790..
Predicted Secondary structure 





































Query SS confidence 















































































Query Sequence  HEVMMRGTFANIRIRNEMVPGVEGGMTRHLPDSDVVSIYDAAMRYKQEQTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRV
Query Conservation   


 








 
       
  
          
 
 
  
   
   




 


 




 

     


 
Alig confidence 




















.

























































Template Conservation   


 
 




 
 
     .

  
   
      
 


  
   
   




 


 




 

     


 
Template Sequence  DAVMARGTFANIRLLNRFLNK. QAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSRDWAAKGPFLLGIKA
Template Known Secondary structure  TTT

TT
TTTT.
STTTTTT



SSBTBS


TTT
Template Predicted Secondary structure 












.























Template SS confidence 















































































   716...720.........730...... ...740.........750.........760.........770.........780.........790....
 
   793......800.........810.........820.........830.........840.........850.........860.........870..
Predicted Secondary structure 































Query SS confidence 















































































Query Sequence  VIAESFERIHRSNLIGMGILPLEFPQGVTRKTLGLTGEEKIDIGDLQNLQPGATVPVTLTRADGSQEVVPCRCRIDTATE
Query Conservation 


 

 







  




 
        
 
 
 
   
     
 

  
   
    
            
  
Alig confidence 






























































....












Template Conservation 


 

 







  




 
        
   
 
   
     
       
    
 ....     
   
  
Template Sequence  VLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIPENLKPQMKVQVKLDTGK. . . . TFQAVMRFDTDVE
Template Known Secondary structure  S
B
TT


TT

T

S
S



SS

TT
TTS
....


S
Template Predicted Secondary structure 




























....


Template SS confidence 















































































   795....800.........810.........820.........830.........840.........850....... ..860.........870
 
   873......880.........890.
Predicted Secondary structure 



Query SS confidence 


















Query Sequence  LTYYQNDGILHYVIRNMLK
Query Conservation        



  
      
Alig confidence 


















Template Conservation        



  
      
Template Sequence  LTYFLNGGILNYMIRKMAK
Template Known Secondary structure  TS
Template Predicted Secondary structure 



Template SS confidence 


















   871........880.........
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions