Job Description P04825 Confidence 100.00% Date Thu Jan 5 10:58:23 GMT 2012 Rank 8 Aligned Residues 660 % Identity 17% Template c3qnfA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the open state of human endoplasmic reticulum2 aminopeptidase 1 erap1 Resolution 3.00 Å

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		11	.	.	.		.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.		.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.						.	.	.	.	.	.	80	.	.	.
Predicted Secondary structure						.																														.																															.	.	.	.	.
Query SS confidence						.																														.																															.	.	.	.	.
Query Sequence		H	D	Y	R	.	A	P	D	Y	Q	I	T	D	I	D	L	T	F	D	L	D	A	Q	K	T	V	V	T	A	V	S	Q	A	V	.	R	H	G	A	S	D	A	P	L	R	L	N	G	E	D	L	K	L	V	S	V	H	I	N	D	E	P	W	T	A	.	.	.	.	.	W	K	E	E	E	G	A	L	V	I
Query Conservation						.																														.																															.	.	.	.	.
Alig confidence						.																														.																															.	.	.	.	.
Template Conservation
Template Sequence		N	K	I	R	L	P	E	Y	V	I	P	V	H	Y	D	L	L	I	H	A	N	L	T	T	L	T	F	W	G	T	T	K	V	E	I	T	A	S	Q	P	T	S	T	I	I	L	H	S	H	H	L	Q	I	S	R	A	T	L	R	K	G	L	S	E	E	P	L	Q	V	L	E	H	P	R	Q	E	Q	I	A	L
Template Known Secondary structure				S	S			T	T														T	T	T	T													S	S											S																							G	G	G	T
Template Predicted Secondary structure
Template SS confidence
		50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.
							84	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.										.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.																																.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.																																.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	S	N	L	P	E	R	F	T	L	K	I	I	N	E	I	S	P	A	A	N	T	A	L	E	G	L	Y	Q	S	G	D	.	.	.	.	.	.	.	.	.	A	L	C	T	Q	C	E	A	E	G	F	R	H	I	T	Y	Y	L	D	R	P	D	V	L	A	R	F	T	T	K	I	I	A	D	K
Query Conservation		.	.	.	.	.																																.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.																			.	.												.	.	.	.	.	.	.	.	.
Template Conservation																									.	.
Template Sequence		L	A	P	E	P	L	L	V	G	L	P	Y	T	V	V	I	H	Y	A	G	N	L	S	.	.	E	T	F	H	G	F	Y	K	S	T	Y	R	T	K	E	G	E	L	R	I	L	A	S	T	Q	F	E	P	T	A	A	R	M	A	F	P	C	F	D	E	P	A	F	K	A	S	F	S	I	K	I	R	R	E	P
Template Known Secondary structure									B	T														B	.	.	S	S	S	S										T	T	S											T	T	T	T	G	G	G	T	S		B			S	T	T	S		B										T
Template Predicted Secondary structure																									.	.
Template SS confidence
		134	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.			.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.
		150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	K	Y	P	F	L	L	S	N	G	N	R	V	A	Q	G	E	L	E	N	G	R	H	W	V	Q	W	Q	D	P	F	P	K	P	C	Y	L	F	A	L	V	A	G	D	F	D	V	L	R	D	T	F	T	T	R	S	G	R	E	V	A	L	E	L	Y	V	D	R	G	N	L	D	R	A	P	W	A	M	T	S
Query Conservation
Alig confidence				.	.																																																.	.	.	.
Template Conservation				.	.																																																.	.	.	.
Template Sequence		R	H	.	.	L	A	I	S	N	M	P	L	V	K	S	V	T	V	A	E	G	L	I	E	D	H	F	D	V	T	V	K	M	S	T	Y	L	V	A	F	I	I	S	D	F	E	S	V	S	K	I	.	.	.	.	T	K	S	G	V	K	V	S	V	Y	A	V	P	D	K	I	N	Q	A	D	Y	A	L	D	A
Template Known Secondary structure		T		.	.					S	S										T	T											S	B		G	G	G															.	.	.	.		T	T										T	T	T	G	G	G	G
Template Predicted Secondary structure				.	.																																																.	.	.	.
Template SS confidence
		212	.			.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260					.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.
		230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	K	N	S	M	K	W	D	E	E	R	F	G	L	E	Y	D	L	D	I	Y	M	I	V	A	V	D	F	F	N	M	G	A	M	E	N	K	G	L	N	I	F	N	S	K	Y	V	L	A	R	T	D	T	A	T	D	K	D	Y	L	D	I	E	R	V	I	G	H	E	Y	F	H	N	W	T	G	N	R	V	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	V	T	L	L	E	F	Y	E	D	Y	F	S	I	P	Y	P	L	P	K	Q	D	L	A	A	I	P	D	F	Q	S	G	A	M	E	N	W	G	L	T	T	Y	R	E	S	A	L	L	F	D	A	E	K	S	S	A	S	S	K	L	G	I	T	M	T	V	A	H	E	L	A	H	Q	W	F	G	N	L	V	T
Template Known Secondary structure														T	S			S	S	S								T	T			S	S					T	T						G	G	G	T				T	T	T	S		T	T																		B	T	T	T
Template Predicted Secondary structure
Template SS confidence
		286	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.
		310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	R	D	W	F	Q	L	S	L	K	E	G	L	T	V	F	R	D	Q	E	F	S	S	D	L	G	S	R	A	V	N	R	I	N	N	V	R	T	M	R	G	L	Q	F	A	E	D	A	S	P	M	A	H	P	I	R	P	D	M	V	I	E	M	N	N	F	Y	T	L	T	V	Y	E	K	G	A	E	V	I	R
Query Conservation
Alig confidence																																											.																			.	.	.	.	.	.
Template Conservation																																											.																			.	.	.	.	.	.
Template Sequence		M	E	W	W	N	D	L	W	L	N	E	G	F	A	K	F	M	E	F	V	S	V	S	V	T	H	P	E	L	K	V	G	D	Y	F	F	G	K	C	F	D	.	A	M	E	V	D	A	L	N	S	S	H	P	V	S	T	P	V	E	.	.	.	.	.	.	N	D	D	V	S	Y	D	K	G	A	C	I	L	N
Template Known Secondary structure			S	S	G	G	G																					G	G	G													.						T	S	T	T				S	S					.	.	.	.	.	.
Template Predicted Secondary structure																																											.																			.	.	.	.	.	.
Template SS confidence
		366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.		.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.							.	.	.	.	.	430	.	.	.	.	.	.	.	.
		390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.		.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.
Predicted Secondary structure																																															.
Query SS confidence																																															.
Query Sequence		M	I	H	T	L	L	G	E	E	N	F	Q	K	G	M	Q	L	Y	F	E	R	H	D	G	S	A	A	T	C	D	D	F	V	Q	A	M	E	D	A	S	N	V	D	L	S	.	H	F	R	R	W	Y	S	Q	S	G	T	P	I	V	T	V	K	D	D	Y	N	P	E	T	E	Q	Y	T	L	T	I	S	Q	R
Query Conservation																																															.
Alig confidence																																							.	.							.																						.	.	.	.	.	.
Template Conservation																																							.	.																													.	.	.	.	.	.
Template Sequence		M	L	R	E	Y	L	S	A	D	A	F	K	S	G	I	V	Q	Y	L	Q	K	H	S	Y	K	N	T	K	N	E	D	L	W	D	S	M	A	.	.	S	I	V	D	V	K	T	M	M	N	T	W	T	L	Q	K	G	F	P	L	I	T	I	T	V	R	G	R	.	.	.	.	.	.	N	V	H	M	K	Q	E
Template Known Secondary structure							S																T	T	T													T	.	.	T														S		S										T	T	.	.	.	.	.	.
Template Predicted Secondary structure																																							.	.																													.	.	.	.	.	.
Template SS confidence
		447	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.			.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.							.	.	.	.	.	.	.
		469	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	P	A	T	P	D	Q	A	E	K	Q	P	L	H	I	P	F	A	I	E	L	Y	D	N	E	G	K	V	I	P	L	Q	K	G	G	H	P	V	N	S	V	L	N	V	T	Q	A	E	Q	T	F	V	F	D	N	V	Y	F	Q	P	V	P	A	L	L	C	E	F	S	A	P	V	K	L	E	Y	K	W	S	D
Query Conservation
Alig confidence					.	.	.	.													.	.	.	.	.	.	.	.	.	.	.	.																												.	.
Template Conservation					.	.	.	.													.	.	.	.	.	.	.	.	.	.	.	.																												.	.
Template Sequence		H	Y	M	.	.	.	.	K	T	G	Y	L	W	H	V	P	L	T	F	.	.	.	.	.	.	.	.	.	.	.	.	I	T	S	K	S	D	M	V	H	R	F	L	L	K	T	K	T	D	V	L	I	L	P	E	E	V	E	.	.	W	I	K	F	N	V	G	M	N	G	Y	Y	I	V	H	Y	E	D	D	G
Template Known Secondary structure					.	.	.	.													.	.	.	.	.	.	.	.	.	.	.	.			S	S			S								S	S							S	S			S	.	.					S	G	G	G		S	S	S					T	T	T
Template Predicted Secondary structure					.	.	.	.													.	.	.	.	.	.	.	.	.	.	.	.																												.	.
Template SS confidence
		548	.	550					.	.	.	.	.	.	.	.	.	560	.	.													.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.			590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.
		549	550		.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.
Predicted Secondary structure				.
Query SS confidence				.
Query Sequence		Q	Q	.	L	T	F	L	M	R	H	A	R	N	D	F	S	R	W	D	A	A	Q	S	L	L	A	T	Y	I	K	L	N	V	A	R	H	Q	Q	G	Q	P	L	S	L	P	V	H	V	A	D	A	F	R	A	V	L	L	D	E	K	I	D	P	A	L	A	A	E	I	L	T	L	P	S	V	N	E	M	A	E
Query Conservation				.
Alig confidence				.																																																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		W	D	S	L	T	G	L	L	K	G	T	H	T	A	V	S	S	N	D	R	A	S	L	I	N	N	A	F	Q	L	V	S	I	G	K	L	S	I	E	K	A	L	D	L	S	L	Y	L	K	H	E	T	E	I	M	P	V	F	Q	G	L	N	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure													G	G	G	S																		T	T	S	S										G	G	G	G	G			S										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		617	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.
		628	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.					.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.
Predicted Secondary structure																				.	.	.	.
Query SS confidence																				.	.	.	.
Query Sequence		L	F	D	I	I	D	P	I	A	I	A	E	V	R	E	A	L	T	.	.	.	.	R	T	L	A	T	E	L	A	D	E	L	L	A	I	Y	N	A	N	Y	Q	S	E	Y	R	V	E	H	E	D	I	A	K	R	T	L	R	N	A	C	L	R	F	L	A	F	G	E	T	H	L	A	D	V	L	V	S	K	Q
Query Conservation																				.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.											.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	E	L	I	P	M	Y	K	L	M	E	K	R	D	M	N	E	V	E	T	Q	F	K	A	F	L	I	R	L	L	R	D	L	I	D	K	Q	T	W	T	D	E	G	S	V	S	E	R	M	L	R	S	Q	L	L	L	L	A	C	V	H	N	Y	Q	P	C	V	Q	R	A	E	G	Y
Template Known Secondary structure		.	.	.	.	.	.	.	.												S	S																											S		S	S	T	T													T	T	T	T		T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.
Template SS confidence
										679	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750
		704	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740
Predicted Secondary structure
Query SS confidence
Query Sequence		F	H	E	A	N	N	M	T	D	A	L	A	A	L	S	A	A	V	A	A	Q	L	P	C	R	D	A	L	M	Q	E	Y	D	D	K	W	H
Query Conservation
Alig confidence																									.	.	.
Template Conservation																									.	.	.
Template Sequence		F	R	K	W	K	E	S	Q	I	E	F	A	L	C	R	T	Q	N	I	E	E	N	I	.	.	.	G	W	M	D	K	N	F	D	K	I	R
Template Known Secondary structure					T	T										S									.	.	.
Template Predicted Secondary structure																									.	.	.
Template SS confidence
		751	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.				.	.	.	.	.	.	780	.	.	.	.