Job Description P04825 Confidence 100.00% Date Thu Jan 5 10:58:23 GMT 2012 Rank 2 Aligned Residues 855 % Identity 35% Template c3ebhA_ PDB info PDB header:hydrolase inhibitor Chain: A: PDB Molecule:m1 family aminopeptidase; PDBTitle: structure of the m1 alanylaminopeptidase from malaria complexed with2 bestatin Resolution 1.65 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.		.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.				.	.	.	.	.	.	.	80
Predicted Secondary structure																																								.																															.	.	.
Query SS confidence																																								.																															.	.	.
Query Sequence		P	Q	A	K	Y	R	H	D	Y	R	A	P	D	Y	Q	I	T	D	I	D	L	T	F	D	L	D	A	Q	K	T	V	V	T	A	V	S	Q	A	.	V	R	H	G	A	S	D	A	P	L	R	L	N	G	E	D	L	K	L	V	S	V	H	I	N	D	E	P	W	T	.	.	.	A	W	K	E	E	E	G	A
Query Conservation																																								.																															.	.	.
Alig confidence																																								.																															.	.	.
Template Conservation
Template Sequence		P	K	I	H	Y	R	K	D	Y	K	P	S	G	F	I	I	N	Q	V	T	L	N	I	N	I	H	D	Q	E	T	I	V	R	S	V	L	D	M	D	I	S	K	H	N	V	G	E	D	L	V	F	D	G	V	G	L	K	I	N	E	I	S	I	N	N	K	K	L	V	E	G	E	E	Y	T	Y	D	N	E	F
Template Known Secondary structure							G	G	G					S														S	S														T	T			S									S									T	T					B	T	T	T					S	S
Template Predicted Secondary structure
Template SS confidence
		196	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.
		81	.	.	.	.				.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.
Predicted Secondary structure							.	.	.
Query SS confidence							.	.	.
Query Sequence		L	V	I	S	N	.	.	.	L	P	E	R	F	T	L	K	I	I	N	E	I	S	P	A	A	N	T	A	L	E	G	L	Y	Q	S	G	D	A	L	C	T	Q	C	E	A	E	G	F	R	H	I	T	Y	Y	L	D	R	P	D	V	L	A	R	F	T	T	K	I	I	A	D	K	I	K	Y	P	F	L	L	S
Query Conservation							.	.	.
Alig confidence							.	.	.
Template Conservation
Template Sequence		L	T	I	F	S	K	F	V	P	K	S	K	F	A	F	S	S	E	V	I	I	H	P	E	T	N	Y	A	L	T	G	L	Y	K	S	K	N	I	I	V	S	Q	C	E	A	T	G	F	R	R	I	T	F	F	I	D	R	P	D	M	M	A	K	Y	D	V	T	V	T	A	D	K	E	K	Y	P	V	L	L	S
Template Known Secondary structure						G	G	G	S		S	S	S											G	G	G		T	T		S						T	T							T	T	T	T	G	G	G	T	S		B			S	T	T													T	T	T
Template Predicted Secondary structure
Template SS confidence
		276	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.
		158	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.		.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Predicted Secondary structure																																																	.
Query SS confidence																																																	.
Query Sequence		N	G	N	R	V	A	Q	G	E	L	E	N	G	R	H	W	V	Q	W	Q	D	P	F	P	K	P	C	Y	L	F	A	L	V	A	G	D	F	D	V	L	R	D	T	F	T	T	R	.	S	G	R	E	V	A	L	E	L	Y	V	D	R	G	N	L	D	R	A	P	W	A	M	T	S	L	K	N	S	M	K	W
Query Conservation																																																	.
Alig confidence																																																	.
Template Conservation
Template Sequence		N	G	D	K	V	N	E	F	E	I	P	G	G	R	H	G	A	R	F	N	D	P	P	L	K	P	C	Y	L	F	A	V	V	A	G	D	L	K	H	L	S	A	T	Y	I	T	K	Y	T	K	K	K	V	E	L	Y	V	F	S	E	E	K	Y	V	S	K	L	Q	W	A	L	E	C	L	K	K	S	M	A	F
Template Known Secondary structure		S	S									T	T	T														G	G	G																		S	S	S												G	G	G	G	G	G	G
Template Predicted Secondary structure
Template SS confidence
		356	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	E	E	R	F	G	L	E	Y	D	L	D	I	Y	M	I	V	A	V	D	F	F	N	M	G	A	M	E	N	K	G	L	N	I	F	N	S	K	Y	V	L	A	R	T	D	T	A	T	D	K	D	Y	L	D	I	E	R	V	I	G	H	E	Y	F	H	N	W	T	G	N	R	V	T	C	R	D	W	F	Q	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	E	D	Y	F	G	L	E	Y	D	L	S	R	L	N	L	V	A	V	S	D	F	N	V	G	A	M	E	N	K	G	L	N	I	F	N	A	N	S	L	L	A	S	K	K	N	S	I	D	F	S	Y	A	R	I	L	T	V	V	G	H	E	Y	F	H	Q	Y	T	G	N	R	V	T	L	R	D	W	F	Q	L
Template Known Secondary structure												S	S								S			S	S	S					T	T						G	G	G	T				T	T	T	S		T																T	T	T	B	T	T	T	B			S	S	G	G	G
Template Predicted Secondary structure
Template SS confidence
		436	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	L	K	E	G	L	T	V	F	R	D	Q	E	F	S	S	D	L	G	S	R	A	V	N	R	I	N	N	V	R	T	M	R	G	L	Q	F	A	E	D	A	S	P	M	A	H	P	I	R	P	D	M	V	I	E	M	N	N	F	Y	T	L	T	V	Y	E	K	G	A	E	V	I	R	M	I	H	T	L	L	G
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	L	K	E	G	L	T	V	H	R	E	N	L	F	S	E	E	M	T	K	T	V	T	T	R	L	S	H	V	D	L	L	R	S	V	Q	F	L	E	D	S	S	P	L	S	H	P	I	R	P	E	S	Y	V	S	M	E	N	F	Y	T	T	T	V	Y	D	K	G	S	E	V	M	R	M	Y	L	T	I	L	G
Template Known Secondary structure																							T																			T	S	T	T				S	S		S			S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		516	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.
		397	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.								.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																		.	.	.	.	.	.	.
Query SS confidence																																		.	.	.	.	.	.	.
Query Sequence		E	E	N	F	Q	K	G	M	Q	L	Y	F	E	R	H	D	G	S	A	A	T	C	D	D	F	V	Q	A	M	E	D	A	.	.	.	.	.	.	.	S	N	V	D	L	S	H	F	R	R	W	Y	S	Q	S	G	T	P	I	V	T	V	K	D	D	Y	N	P	E	T	E	Q	Y	T	L	T	I	S	Q	R	T
Query Conservation																																		.	.	.	.	.	.	.
Alig confidence																																		.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	E	Y	Y	K	K	G	F	D	I	Y	I	K	K	N	D	G	N	T	A	T	C	E	D	F	N	Y	A	M	E	Q	A	Y	K	M	K	K	A	D	N	S	A	N	L	N	Q	Y	L	L	W	F	S	Q	S	G	T	P	H	V	S	F	K	Y	N	Y	D	A	E	K	K	Q	Y	S	I	H	V	N	Q	Y	T
Template Known Secondary structure																	T	T	S																				T		T	T				T	G	G	G							S												T	T	T	T
Template Predicted Secondary structure
Template SS confidence
		596	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.
		470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	A	T	P	D	Q	A	E	K	Q	P	L	H	I	P	F	A	I	E	L	Y	D	N	E	G	K	V	I	P	L	Q	K	G	G	H	P	V	N	S	V	L	N	V	T	Q	A	E	Q	T	F	V	F	D	N	V	Y	F	Q	P	V	P	A	L	L	C	E	F	S	A	P	V	K	L	E	Y	K	W	S	D	Q
Query Conservation
Alig confidence																															.	.	.	.	.	.
Template Conservation																															.	.	.	.	.	.
Template Sequence		K	P	D	E	N	Q	K	E	K	K	P	L	F	I	P	I	S	V	G	L	I	N	P	E	N	G	K	E	M	.	.	.	.	.	.	I	S	Q	T	T	L	E	L	T	K	E	S	D	T	F	V	F	N	N	I	A	V	K	P	I	P	S	L	F	R	G	F	S	A	P	V	Y	I	E	D	Q	L	T	D	E
Template Known Secondary structure					S	S		S	S															T	T	T			B		.	.	.	.	.	.	S									S	S							S				S							S	T	T			S	S	S
Template Predicted Secondary structure																															.	.	.	.	.	.
Template SS confidence
		676	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.							.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.
		550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.									.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.
Predicted Secondary structure																																		.	.	.	.	.	.	.	.
Query SS confidence																																		.	.	.	.	.	.	.	.
Query Sequence		Q	L	T	F	L	M	R	H	A	R	N	D	F	S	R	W	D	A	A	Q	S	L	L	A	T	Y	I	K	L	N	V	A	.	.	.	.	.	.	.	.	R	H	Q	Q	G	Q	P	L	S	L	P	V	H	V	A	D	A	F	R	A	V	L	L	D	E	K	I	D	P	A	L	A	A	E	I	L	T	L	P	S
Query Conservation																																		.	.	.	.	.	.	.	.
Alig confidence																																		.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	R	I	L	L	L	K	Y	D	S	D	A	F	V	R	Y	N	S	C	T	N	I	Y	M	K	Q	I	L	M	N	Y	N	E	F	L	K	A	K	N	E	K	L	E	S	F	Q	L	T	P	V	N	A	Q	F	I	D	A	I	K	Y	L	L	E	D	P	H	A	D	A	G	F	K	S	Y	I	V	S	L	P	Q
Template Known Secondary structure											S																															T		S	S																			T		T	T	S									T	S
Template Predicted Secondary structure
Template SS confidence
		750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.
		622	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.										.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.
Predicted Secondary structure																																													.	.	.	.	.	.	.	.	.
Query SS confidence																																													.	.	.	.	.	.	.	.	.
Query Sequence		V	N	E	M	A	E	L	F	D	I	I	D	P	I	A	I	A	E	V	R	E	A	L	T	R	T	L	A	T	E	L	A	D	E	L	L	A	I	Y	N	A	N	Y	.	.	.	.	.	.	.	.	.	Q	S	E	Y	R	V	E	H	E	D	I	A	K	R	T	L	R	N	A	C	L	R	F	L	A	F	G	E
Query Conservation																																													.	.	.	.	.	.	.	.	.
Alig confidence																																													.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		D	R	Y	I	I	N	F	V	S	N	L	D	T	D	V	L	A	D	T	K	E	Y	I	Y	K	Q	I	G	D	K	L	N	D	V	Y	Y	K	M	F	K	S	L	E	A	K	A	D	D	L	T	Y	F	N	D	E	S	H	V	D	F	D	Q	M	N	M	R	T	L	R	N	T	L	L	S	L	L	S	K	A	Q
Template Known Secondary structure						G	G	G		T	T	B																																				T			T	T	T	T		T	T																							T	T
Template Predicted Secondary structure
Template SS confidence
		830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.
		693	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	H	L	A	D	V	L	V	S	K	Q	F	H	E	A	N	N	M	T	D	A	L	A	A	L	S	A	A	V	A	A	Q	L	P	C	R	D	A	L	M	Q	E	Y	D	D	K	W	H	Q	N	G	L	V	M	D	K	W	F	I	L	Q	A	T	S	P	A	A	N	V	L	E	T	V	R	G	L	L	Q	H	R
Query Conservation
Alig confidence															.																			.	.
Template Conservation															.																			.	.
Template Sequence		Y	P	N	I	L	N	E	I	I	E	H	S	K	.	S	P	Y	P	S	N	W	L	T	S	L	S	V	S	A	Y	F	D	.	.	K	Y	F	E	L	Y	D	K	T	Y	K	L	S	K	D	D	E	L	L	L	Q	E	W	L	K	T	V	S	R	S	D	R	K	D	I	Y	E	I	L	K	K	L	E	N	E	V
Template Known Secondary structure			T	T									T	T	.		S												G	G	G	S	T	.	.	T													T	T	S													T				T	T												T
Template Predicted Secondary structure															.																			.	.
Template SS confidence
		910	.	.	.	.	.	.	.	.	.	920	.	.		.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940			.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.
		773	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	F	T	M	S	N	P	N	R	I	R	S	L	I	G	A	F	A	G	S	N	P	A	A	F	H	A	E	D	G	S	G	Y	L	F	L	V	E	M	L	T	D	L	N	S	R	N	P	Q	V	A	S	R	L	I	E	P	L	I	R	L	K	R	Y	D	A	K	R	Q	E	K	M	R	A	A	L	E	Q	L	K
Query Conservation
Alig confidence																				.
Template Conservation																				.
Template Sequence		L	K	D	S	K	N	P	N	D	I	R	A	V	Y	L	P	F	T	.	N	N	L	R	R	F	H	D	I	S	G	K	G	Y	K	L	I	A	E	V	I	T	K	T	D	K	F	N	P	M	V	A	T	Q	L	C	E	P	F	K	L	W	N	K	L	D	T	K	R	Q	E	L	M	L	N	E	M	N	T	M	L
Template Known Secondary structure		T	T	T												T	G	G	G	.	G						T		T	T	S															T	T								T	T	G	G	G	G	G	G	G	G	B
Template Predicted Secondary structure																				.
Template SS confidence
		987	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.		.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.
		853	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	L	E	N	L	S	G	D	L	Y	E	K	I	T	K	A	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Q	E	P	Q	I	S	N	N	L	K	E	Y	L	L	R	L	T
Template Known Secondary structure		T		T	T													T
Template Predicted Secondary structure
Template SS confidence
		1066	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.