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Job DescriptionP04825
Confidence100.00%DateThu Jan 5 10:58:23 GMT 2012
Rank1Aligned Residues866
% Identity100%Templatec3b37A_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of e. coli aminopeptidase n in complex with tyrosine
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   5....10.........20.........30.........40.........50.........60.........70.........80....
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Query Sequence  PQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVIS
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Template Conservation 
      

 
    
 
  
  

      
     
         
 

   
 
 

 
 
            
 
 
Template Sequence  PQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVIS
Template Known Secondary structure 


GGG



S

SS

S
TT


SS
TT

STT
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   5....10.........20.........30.........40.........50.........60.........70.........80....
 
   85....90.........100.........110.........120.........130.........140.........150.........160....
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Query Sequence  NLPERFTLKIINEISPAANTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQ
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Template Conservation         
 
             


 
     

 

  

  


 
 
  



 
 
  
     
 



     
Template Sequence  NLPERFTLKIINEISPAANTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQ
Template Known Secondary structure  S

S
GGG

S

TT
TTTTGGGTSSB

STT

TTT

SS
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   85....90.........100.........110.........120.........130.........140.........150.........160....
 
   165....170.........180.........190.........200.........210.........220.........230.........240....
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Query Sequence  GELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEERFGLE
Query Conservation       
     
  
 

 


 
  

 
          

  
 
  
  
        

      
   
  

 
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Template Conservation       
     
    
  


 
  

 
        
 

  
 
  
  
        

      
   
  

  
Template Sequence  GELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEERFGLE
Template Known Secondary structure 
STT
GGG




TT


TT
GGG



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   165....170.........180.........190.........200.........210.........220.........230.........240....
 
   245....250.........260.........270.........280.........290.........300.........310.........320....
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Query Sequence  YDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTV
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Template Conservation 

  
   
 



  




 

       

                












 

   
 








 
Template Sequence  YDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTV
Template Known Secondary structure 

SSS

SSS

TTGGGT


TTT

TTTBTTTSSGGG
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   245....250.........260.........270.........280.........290.........300.........310.........320....
 
   325....330.........340.........350.........360.........370.........380.........390.........400....
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Query Sequence  FRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGM
Query Conservation 
                   
          
    
 

           
  
 
 


 




   

 
 
  

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Template Conservation 
                              
    
 

           
  
 
 


 

 

   

 
 
  

Template Sequence  FRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGM
Template Known Secondary structure  S
TTSTT


SS
SS
GGGG

Template Predicted Secondary structure 




















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   325....330.........340.........350.........360.........370.........380.........390.........400....
 
   405....410.........420.........430.........440.........450.........460.........470.........480....
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Query Sequence  QLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTVKDDYNPETEQYTLTISQRTPATPDQAEKQPLHIP
Query Conservation    

       

  

  
 
  

 

  
  
  
 
 
 
 
    
       

  
               

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Template Conservation    
        

  

  
 
  

 

  
  
  
 
 
 
 
    
       


 
               

Template Sequence  QLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTVKDDYNPETEQYTLTISQRTPATPDQAEKQPLHIP
Template Known Secondary structure  TT




TTTT

S

TTTT


BTTBS





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   405....410.........420.........430.........440.........450.........460.........470.........480....
 
   485....490.........500.........510.........520.........530.........540.........550.........560....
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Query Sequence  FAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSR
Query Conservation 
   
    
                 
               
   
    
    
 
      
  
   
 
   
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Template Conservation 
   
    
                 
     
         
   
    
    
 
      
  
   
 
   
Template Sequence  FAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSR
Template Known Secondary structure 
TTS
B


TT

S
SS



S

STT

SS





SS
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   485....490.........500.........510.........520.........530.........540.........550.........560....
 
   565....570.........580.........590.........600.........610.........620.........630.........640....
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Query Sequence  WDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEVREAL
Query Conservation    
   
                               
          
  
 


   
       
       
  
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Template Conservation    
   
                               
          
  
 

    
       
          
Template Sequence  WDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEVREAL
Template Known Secondary structure  TT






SSS
TS


TT
SS

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   565....570.........580.........590.........600.........610.........620.........630.........640....
 
   645....650.........660.........670.........680.........690.........700.........710.........720....
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Query Sequence  TRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRNACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAVAAQ
Query Conservation     

                            
 

   
              
   
  
   

   

 

    
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Template Conservation     

                            
 

   
                  
  
   

   

 

    
Template Sequence  TRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRNACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAVAAQ
Template Known Secondary structure  TT

SS


STSS
SSTT
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   645....650.........660.........670.........680.........690.........700.........710.........720....
 
   725....730.........740.........750.........760.........770.........780.........790.........800....
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Query Sequence  LPCRDALMQEYDDKWHQNGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAEDGSG
Query Conservation         
  
        
     
   
          
  
  
  
   


  


   
   
   

   
 
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Template Conservation         
  
              
  

          
  
  
  
   


  
 
   
   
   

   
 
Template Sequence  LPCRDALMQEYDDKWHQNGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAEDGSG
Template Known Secondary structure 
TTTT
T


TTTT
TT

TT

T
TTS
Template Predicted Secondary structure 































Template SS confidence 















































































   725....730.........740.........750.........760.........770.........780.........790.........800....
 
   805....810.........820.........830.........840.........850.........860.........870
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Query Sequence  YLFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA
Query Conservation 
      
  

  

  


                      
        

    
     
 
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Template Conservation 
  

  
  

  

  


                      
        

    
 
 
 
 
Template Sequence  YLFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA
Template Known Secondary structure 
GGGGGGGGS
T
TT


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   805....810.........820.........830.........840.........850.........860.........870
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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