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Job DescriptionP04825
Confidence100.00%DateThu Jan 5 10:58:23 GMT 2012
Rank5Aligned Residues803
% Identity15%Templatec2xdtA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the soluble domain of human2 endoplasmic reticulum aminopeptidase 1 erap1
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   11... .....20.........30.........40... ......50.........60.........70... ......80...
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Query Sequence  HDYR. APDYQITDIDLTFDLDAQKTVVTAVSQAV. RHGASDAPLRLNGEDLKLVSVHINDEPWTA. . . . . WKEEEGALVI
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Template Conservation     


    
  
 
 
  
       
   
          
 
    
 
  
                     
 
Template Sequence  NKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGLSEEPLQVLEHPRQEQIAL
Template Known Secondary structure 

SS

SSTTTTSS

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TTTT
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   50.........60.........70.........80.........90.........100.........110.........120.........
 
   84.....90.........100.........110.... .....120.........130.........140.........
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Query Sequence  . . . . . SNLPERFTLKIINEISPAANTALEGLYQSGD. . . . . . . . . ALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADK
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Template Sequence  LAPEPLLVGLPYTVVIHYAGNLS. . ETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREP
Template Known Secondary structure 
TT


B..SSSS
TTS

TTTTS
B

STTS
B
T
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   134.....140.........150...... ...160.........170.........180.........190.........200.........210.
 
   150.........160.........170.........180.........190.........200.........210.........220.........
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Query Sequence  IKYPFLLSNGNRVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTS
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Template Sequence  RH. . LAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKI. . . . TKSGVKVSVYAVPDKINQADYALDA
Template Known Secondary structure  T
..SS
TT



SB
GGG



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TT


TTTGGG
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   212. ......220.........230.........240.........250.........260 .........270.........280.....
 
   230.........240.........250.........260.........270.........280.........290.........300.........
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Query Sequence  LKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVT
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Template Sequence  AVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVT
Template Known Secondary structure  TT



SSSS
SSS

TTGGGT


TTT

TTTBTTT
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   286...290.........300.........310.........320.........330.........340.........350.........360.....
 
   310.........320.........330.........340.........350.........360....... ..370.........380.......
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Query Sequence  CRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIRPD. . MVIEMNNFYTLTVYEKGAEV
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Template Sequence  MEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFD. AMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACI
Template Known Secondary structure  SSGGGT
GGG
GGGG.TSTT


SS



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   366...370.........380.........390.........400...... ...410.........420.........430.........440....
 
   388.390.........400.........410.........420.........430.... .....440.........450.........460......
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Query Sequence  IRMIHTLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLS. HFRRWYSQSGTPIVTVKDDYNPETEQYTLTIS
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Template Sequence  LNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMAS. IGVDVKTMMNTWTLQKGFPLITITVRGR. . . . . . NVHMK
Template Known Secondary structure  S
TT
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   445....450.........460.........470.........480.... .....490.........500.........510.. .....
 
   467..470.........480.........490.........500.........510.........520.........530.........540......
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Query Sequence  QRTPATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKW
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Template Sequence  QEHYMK. . GDTGYLWHVPLTF. . . . . . . . . . . . ITSKSDMVHRFLLKTKTDVLILPEEVE. . WIKFNVGMNGYYIVHYED
Template Known Secondary structure 

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SS

SS
SS

S..
SGGG
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T
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   546...550. ........560.... .....570.........580.........590. ........600.........
 
   547..550 .........560.........570.........580.........590.........600.......
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Query Sequence  SDQQ. LTFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEK. . . . . . . . . . . . . . . . . .
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Template Conservation    
  
   
      
    
  

 
   

  
 
     
 

  
  
     
  
   
  
   
       
Template Sequence  DGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNE
Template Known Secondary structure  T
GGGS
TTTSS
GGGGG


TSS
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   615....620.........630.........640.........650.........660.........670.........680.........690....
 
   608.610.........620.........630.........640.........650.........660.........670.........680.......
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Query Sequence  IDPALAAEILTLPSVNEMAELFDIIDPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRNACLRF
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Template Sequence  VETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFA.
Template Known Secondary structure  T

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TTT
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   695....700.........710.........720.........730.........740.........750.........760.........770...
 
   688.690.........700.........710.........720.........730.........740.........750.........760.......
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Query Sequence  LAFGETHLADVLVSKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWHQNGLVMDKWFILQATSPAANVLETVRG
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Template Sequence  . VGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNK. . . EKLQWLLDESFKGDKIKT. . . . . . . . . . . QEFPQILTL
Template Known Secondary structure  .TTSTT


TT


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G...........GG
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   774.....780.........790.........800.........810. ........820......... 830........
 
   768.770.........780.........790.........800.........810...... ...820.........830.........840......
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Query Sequence  LLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAEDGSGYLFLVEMLTDLN. SRNPQVASRLIEPLIRLKRYDAKRQEKMRA
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Template Sequence  IGRNPV. . . . . . . . GYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQ
Template Known Secondary structure  TSTT........TT
TT
TTTT

STGGGTTT
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   839840.... .....850.........860.........870.........880.........890.........900.........910
 
   847..850.........860.........
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Query Sequence  ALEQLKGLENLSGDLYEKITKAL
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Template Conservation   

 
  

 
       
  

Template Sequence  TIETIEENIGWMDKNFDKIRVWL
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   911........920.........930...
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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