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Job DescriptionP04825
Confidence100.00%DateThu Jan 5 10:58:23 GMT 2012
Rank3Aligned Residues859
% Identity47%Templatec2gtqA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis
Resolution2.05 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   6...10.........20.........30.........40.........50.........60.........70.........80.....
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Query Sequence  QAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISN
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Template Conservation 
  
  

 
  
 
    
  

      
   
 
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Template Sequence  TVHYLKDYQTPAYHILKTDLHFDINEPQTVVKSRLTVEPQ. RVGEPLVLDG. SAKLLSVKINGAAADYVLEGETLTIAGV
Template Known Secondary structure 

GGG



S
SS
S.STTS

.
STT


TTS

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   4.....10.........20.........30.........40... ......50... ......60.........70.........80.
 
   86...90.........100.........110.........120.........130.........140.........150.........160.....
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Query Sequence  LPERFTLKIINEISPAANTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQG
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Template Conservation        
 
             


 
     

 

  

  


 
 
  



 
 
  
     
 



      
Template Sequence  PSERFTVEVETEILPAENKSLXGLYASGGNLFTQCEPEGFRKITFYIDRPDVXSKFTTTIVADKKRYPVLLSNGNKIDGG
Template Known Secondary structure 
SS

GGG

S
STT
TTTTGGGTS
B

STT

BTTT

SS
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   82.......90.........100.........110.........120.........130.........140.........150.........160.
 
   166...170.........180.........190.........200.........210.........220.........230.........240.....
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Query Sequence  ELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEERFGLEY
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Template Conservation            
    

 


 
  

 
           
  
 
     
        

      
   
  

  
Template Sequence  EFSDGRHWVKWEDPFSKPSYLFALVAGDLAVTEDYFTTXSGRNVKIEFYTTEADKPKVGFAVESLKNAXKWDETRFGLEY
Template Known Secondary structure 
TTS

S
B
GGG




TTS

TTTGGG




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   162.......170.........180.........190.........200.........210.........220.........230.........240.
 
   246...250.........260.........270.........280.........290.........300.........310.........320.....
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Query Sequence  DLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVF
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Template Conservation 
  
   



 
  




 

       

                















   
 








 
Template Sequence  DLDIFXVVAVGDFNXGAXENKGLNIFNTKFVLADSRTATDTDFEGIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVF
Template Known Secondary structure 
SSSS
SSS

TTGGGT


TTT

TTTBTTTBSSGGG
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   242.......250.........260.........270.........280.........290.........300.........310.........320.
 
   326...330.........340.........350.........360.........370.........380.........390.........400.....
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Query Sequence  RDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQ
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Template Sequence  RDQEFSGDRASRAVRRIENIRLLRQHQFPEDAGPTAHPVRPASYEEXNNFYTXTVYEKGAEVVRXYHTLLGEEGFQKGXK
Template Known Secondary structure  S
STT


SS
SS
GGGG
S
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   322.......330.........340.........350.........360.........370.........380.........390.........400.
 
   406...410.........420.........430.........440.........450.........460.........470.........480.....
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Query Sequence  LYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTVKDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPF
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Template Conservation   

       

  

   

  

 

  
  
  
 
 
 
 
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Template Sequence  LYFQRHDGQAVTCDDFRAAXADANGINLDQFALWYSQAGTPVLEAEGRLK. . NNIFELTVKQTVPPTPDXTDKQPXXIPV
Template Known Secondary structure  TT

T


GGGG

S

..TT


BTTBS





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   402.......410.........420.........430.........440.........450. ........460.........470.........
 
   486...490.........500.... .....510.........520.........530.........540.........550.........560....
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Query Sequence  AIELYDNEGKVIPLQKGGH. PVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSR
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Template Conservation                             
                    
       

        
   
  
 
   
Template Sequence  KVGLLNRNGEAVAFDYQGKRATEAVLLLTEAEQTFLLEGVTEAVVPSLLRGFSAPVHLNYPYSDDDLLLLLAHDSDAFTR
Template Known Secondary structure 
TT

B


SS
S

SSB


S

STT

SS





S
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   480.........490.........500.........510.........520.........530.........540.........550.........
 
   565....570.........580.........590.........600.........610.........620.........630.........640....
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Query Sequence  WDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEVREAL
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Template Conservation    
   
                               
          
    

            
          
Template Sequence  WEAAQTLYRRAVAANLATLSDGVELPKHEKLLAAVEKVISDDLLDNAFKALLLGVPSEAELWDGAENIDPLRYHQAREAL
Template Known Secondary structure  T






SSS
T



TTT
SSB
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   560.........570.........580.........590.........600.........610.........620.........630.........
 
   645....650.........660..... ....670.........680.........690.........700.........710.........720.
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Query Sequence  TRTLATELADELLAIYNANYQ. . . SEYRVEHEDIAKRTLRNACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAV
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Template Conservation                                      
 

   
                              

 

 
Template Sequence  LDTLAVHFLPKWHELNRQAAKQENQSYEYSPEAAGWRTLRNVCRAFVLRADPAHIETVAEKYGEXAQNXTHEWGILSAVN
Template Known Secondary structure  TTT

S


TTT
SST
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   640.........650.........660.........670.........680.........690.........700.........710.........
 
   722.......730.........740.........750.........760.........770.........780.........790.........800.
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Query Sequence  AAQLPCRDALMQEYDDKWHQNGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAED
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Template Conservation            
                     
          
  
     
   


  
 
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Template Sequence  GNESDTRNRLLAQFADKFSDDALVXDKYFALVGSSRRSDTLQQVRTALQHPKFSLENPNKARSLIGSFSR. NVPHFHAED
Template Known Secondary structure  T

STTT


STTTTSTT

TT
T.
T
TT
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   720.........730.........740.........750.........760.........770.........780......... 790........
 
   802.......810.........820.........830.........840.........850.........860.........
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Query Sequence  GSGYLFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKAL
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Template Conservation 
 

  
   
  
   

  
 
    
                 

 
     

    

  
 
Template Sequence  GSGYRFIADKVIEIDRFNPQVAARLVQAFNLCNKLEPHRKNLVKQALQRIRAQEGLSKDVGEIVGKIL
Template Known Secondary structure  STT
GGGGTTGGGB
TSTT

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   799800.........810.........820.........830.........840.........850.........860......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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