|   |
18 | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | Q | I | T | D | I | D | L | T | F | D | L | D | A | Q | K | T | V | V | T | A | V | S | Q | A | V | R | H | G | A | S | D | A | P | L | R | L | N | G | E | D | L | K | L | V | S | V | H | I | N | D | E | P | W | T | A | W | K | E | E | E | G | A | L | V | I | S | N | L | P | E | R | F | T | L | K | I | I | N | E |
Query Conservation |   |
  |   |
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |
|   |
|   |
|   |
|   |   | . | . | . |   |   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |
|   |
|   |
|   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
Template Sequence |   |
M | E | V | E | K | Y | D | L | T | L | D | F | D | I | Q | K | R | T | F | N | G | T | E | T | I | T | A | . |
. |
. |
D | A | G | D | I | V | L | D | A | V | G | L | Q | I | N | W | M | K | V | N | G | R | D | T | . |
A | F | T | Y | D | G | Q | T | V | R | A | P | G | D | S | Q | P | Q | K | I | E | I | S | F | A |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |  | . | . | . |
| S | S |
|  |  |  |  |
| S | S |
|  |  |  |  |  |  |  | T | T |  |  |
| . |
|
|  |  |
| S | S |  |  |  |  |
|
|
| S | S |
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  | . |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | |
|
|
. | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . |
  |
  |   |
98 | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
|
. | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
| . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | S | P | A | A | N | T | A | L | E | G | L | Y | Q | S | G | D | . |
. |
. |
A | L | C | T | Q | C | E | A | E | G | F | R | H | I | T | Y | Y | L | D | R | P | D | V | L | A | R | F | T | T | K | I | I | A | D | K | I | K | Y | P | F | L | L | S | N | G | N | R | V | A | Q | G | E | L | E | N | G | R | H | W | V |
Query Conservation |   |
  |   |
|   |   |   |   |   |
|   |
|
|
|   |
|   |   | . | . | . |   |   |   |
|
|   |
|
|   |   |
|
|   |   |
|
|
|   |
|   |
|   |   |
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
Template Conservation |   |
|   |   | . | . |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
|   |   |
|
|
|   |
|
|
|   |   |
|
|   |
|   |
|   |
|   |   |
|   |   |   | . | . |   |   |
|
|
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
Template Sequence |   |
G | K | V | . |
. |
S | D | S | L | S | G | I | Y | Y | A | G | R | E | N | G | M | I | T | T | H | F | E | A | T | D | A | R | R | M | F | P | C | V | D | H | P | A | Y | K | A | V | F | A | I | T | V | V | I | D | K | D | Y | . |
. |
D | A | I | S | N | M | P | P | K | R | I | E | V | . |
. |
S | E | R | K | V | V |
Template Known Secondary structure |   |
 |  |
| . | . | B | S | S | S | S |  |  |  |  |  | S | S | T | T |
|  |  |  |  |  |
| T | T | T |
| G | G | G | T | S |
| B |
|
|
| T | T | S |
| B |  |  |  |  |  |  |  |  |
| T | T |
| . | . |  |  |  |  | S | S |
|  |  |  |  |  |  | . | . | S | S | S |  |  |  |
Template Predicted Secondary structure |   |
 |  |
| . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |
|
|
|  |  |  |  |  |  | . | . |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
77 | . | . | |
|
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | |
|
. | . | . | . | . | . | . | . | 140 | . | . | . | . | |
|
. | . | . | . | . | 150 |
  |
  |   |
175 | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | W | Q | D | P | F | P | K | P | C | Y | L | F | A | L | V | A | G | D | F | D | V | L | R | D | T | F | T | T | R | S | G | R | E | V | A | L | E | L | Y | V | D | R | G | N | L | D | R | A | P | W | A | M | T | S | L | K | N | S | M | K | W | D | E | E | R | F | G | L | E | Y | D | L | D | I | Y | M | I | V | A |
Query Conservation |   |
  |
|   |   |
|   |
|
|   |
|
|
|   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |
|
|
|   |   |
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |
|
|   |
|
|
|   |
|   |   |
|
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |
|   |
Template Sequence |   |
E | F | Q | D | T | P | R | M | S | T | Y | L | L | Y | V | G | I | G | K | F | R | Y | E | Y | E | K | . |
. |
. |
. |
. |
. |
. |
Y | R | D | I | D | L | I | L | A | S | L | K | D | I | R | S | K | Y | P | L | D | M | A | R | K | S | V | E | F | Y | E | N | Y | F | G | I | P | Y | A | L | P | K | M | H | L | I | S |
Template Known Secondary structure |   |
 |  |
|
|
|
| S | B |
| G | G | G |
|
|  |  |  |  |
|
|  |  |  |  |  |  | . | . | . | . | . | . | . |  | T | T |  |  |  |  |  |  |  | S | S |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| S | S | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
151 | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
  |
  |   |
255 | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | D | F | F | N | M | G | A | M | E | N | K | G | L | N | I | F | N | S | K | Y | V | L | A | R | T | D | T | A | T | D | K | D | Y | L | D | I | E | R | V | I | G | H | E | Y | F | H | N | W | T | G | N | R | V | T | C | R | D | W | F | Q | L | S | L | K | E | G | L | T | V | F | R | D | Q | E | F | S | S | D | L |
Query Conservation |   |
|
|
|
|   |   |
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |
|
|
|
|
|   |
|
|
|   |   |   |
|   |   |
|
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |
|   |
|   |
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | P | E | F | G | A | G | A | M | E | N | W | G | A | I | T | F | R | E | I | Y | M | D | I | A | E | N | . |
S | A | V | T | V | K | R | N | S | A | N | V | I | A | H | E | I | A | H | Q | W | F | G | D | L | V | T | M | K | W | W | N | D | L | W | L | N | E | S | F | A | T | F | M | S | Y | K | T | M | D | T | L |
Template Known Secondary structure |   |
 | T | T |
| T | T | S |  |  |
|
| T | T |  |  |  |  |  |  |  |  |  |
|
|
| T | T | . | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | B | T | T | T |  |  |  | S | S | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | |
. | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
  |
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | |
|
. | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | S | R | A | V | N | R | I | N | N | V | R | T | M | R | G | L | Q | F | A | E | D | A | S | P | M | A | H | P | I | R | P | D | . |
. |
M | V | I | E | M | N | N | F | Y | T | L | T | V | Y | E | K | G | A | E | V | I | R | M | I | H | T | L | L | G | E | E | N | F | Q | K | G | M | Q | L | Y | F | E | R | H | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|
|   |
|
|
|
|
|   |   |   |
|
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |
|
|
|   |
|
|   |
|
|   |   |   |
|
|   |
|   |
|   |   |   |
|   |   |
|
|   |   |   |   |
Template Sequence |   |
F | P | E | W | S | F | W | G | D | F | F | V | S | R | T | S | G | A | L | R | S | D | S | L | K | N | T | H | P | I | E | V | D | V | R | D | P | D | E | I | S | Q | I | F | D | E | I | S | Y | G | K | G | A | S | I | L | R | M | I | E | D | Y | A | G | Y | E | E | F | R | K | G | I | S | K | Y | L | N | D | H | K |
Template Known Secondary structure |   |
| T | T | S |
|  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  | T | T | S | S | S |
|
|
| S |
|
|
|
| S | S | S |
| T | T | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
303 | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . |
  |
  |   |
413 | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | |
. | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | S | A | A | T | C | D | D | F | V | Q | A | M | E | D | A | S | N | V | D | L | S | . |
H | F | R | R | W | Y | S | Q | S | G | T | P | I | V | T | V | K | D | D | Y | N | P | E | T | E | Q | Y | T | L | T | I | S | Q | R | T | P | A | T | P | D | Q | A | E | K | Q | P | L | H | I | P | F | A | I | E | L | Y | D |
Query Conservation |   |
  |   |   |
|
|   |   |
|
|   |   |
|   |
|   |   |
|
|   |
|
|   | . |   |
|   |   |
|   |   |
|   |
|   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |
|
|   |
|
|   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|   |
|   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   | . |   |   |   |
|   |
|
|
|   |   |   |   | . | . |
Template Sequence |   |
F | G | N | A | E | G | S | D | L | W | T | A | I | E | D | V | S | G | K | P | V | K | R | V | M | E | Y | W | I | K | N | P | G | Y | P | V | I | K | L | K | R | N | G | R | . |
. |
. |
. |
. |
. |
K | I | T | M | Y | Q | T | R | F | L | L | N | G | E | E | . |
E | G | R | W | P | V | P | V | N | I | K | K | . |
. |
Template Known Secondary structure |   |
T |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  | S |
| S |
|  |  |  |  |
|
|
| S | T | T | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  | . |  |
|
|
|
|  |  |  |  |  |  |  | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
383 | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | |
. | . | . | . | . | . | . | . | 450 | . | . | . | |
|
  |
  |   |
492 | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | E | G | K | V | I | P | L | Q | K | G | G | H | P | V | N | S | V | L | N | V | T | Q | A | E | Q | T | F | V | F | D | N | V | Y | F | Q | P | V | P | A | L | L | C | E | F | S | A | P | V | K | L | E | Y | K | W | S | D | Q | Q | L | T | F | L | M | R | H | A | R | N | D | F | S | R | W | D | A | A | Q | S | L |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|
|
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   | . | . | . |   |   |   |   |   |
|   |   |
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | D | G | V | E | R | I | L | L | E | D | E | A | S | . |
. |
. |
. |
. |
. |
I | E | A | D | G | L | I | K | I | N | A | D | S | A | G | F | Y | R | V | L | Y | D | D | A | T | F | S | D | V | M | G | H | Y | R | D | . |
. |
. |
L | S | P | L | D | R | I | G | L | V |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | S | S |
|  |  |  |  |  |  | S | S |
|  |  | . | . | . | . | . | . |  |  |
| T | T |  |  |  |  | S | G | G | G |
| S | S | S |  |  |  |
|
|  |  |  |  |  |  |  | G | G | G | G | G | G | . | . | . |
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
454 | . | . | . | . | . | 460 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | |
|
|
. | . | . | . | . | . | . | 510 | . | . |
  |
  |   |
572 | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 640 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | T | Y | I | K | L | N | V | A | R | H | Q | Q | G | Q | P | L | S | L | P | V | H | V | A | D | A | F | R | A | V | L | L | D | E | K | I | D | P | A | L | A | A | E | I | L | T | L | P | S | V | N | E | M | A | E | L | F | D | I | I | . |
. |
. |
. |
. |
. |
D | P | I | A | I | A | E | V | R | E | A | L | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |
|   |   |   |   |   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | D | L | F | A | F | L | L | S | G | H | I | D | P | E | T | Y | R | Q | R | I | R | N | F | F | D | D | E | D | H | N | V | I | T | A | I | V | G | Q | M | E | Y | L | R | M | L | T | H | A | F | D | D | D | A | R | A | F | C | R | S | R | M | Q | F | L | T | G | K | Q | D | E | N | L | K | I | A | L | G | R | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | S | S |
|  |  |  |  |  |  |  |  | G | G | G | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
513 | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . |
  |
  |   |
646 | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | T | L | A | T | E | L | A | D | E | L | L | A | I | Y | N | A | N | Y | Q | S | E | Y | R | V | E | H | E | D | I | A | K | R | T | L | R | N | A | C | L | R | F | L | A | F | G | E | T | H | L | A | D | V | L | V | S | K | Q | F | H | E | A | N | N | M | T | D | A | L | A | A | L | S | A | A | V | A | A | Q | L |
Query Conservation |   |
  |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |   |   |
|
|   |
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
Template Sequence |   |
S | R | L | Y | V | M | V | D | E | S | Y | A | E | E | M | S | K | L | F | K | D | F | D | S | A | E | P | E | . |
. |
. |
. |
. |
. |
M | R | S | S | I | A | T | A | Y | A | L | V | T | G | D | . |
. |
L | K | G | L | L | E | K | F | R | S | V | D | R | D | E | D | R | V | R | I | I | S | A | F | G | K | L | K | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  | G | G | G | G | G | T | T | T | S |
|  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| . | . |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
593 | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | |
|
. | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . |
  |
  |   |
726 | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | |
. | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | C | R | D | A | L | M | Q | E | Y | D | D | K | W | H | Q | N | G | L | . |
V | M | D | K | W | F | I | L | Q | A | T | S | P | A | A | N | V | L | E | T | V | R | G | L | L | Q |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
| . |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
Alig confidence |   |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
Template Sequence |   |
N | . |
. |
. |
T | D | L | S | T | V | Y | G | M | V | E | K | T | E | I | K | K | Q | D | M | I | S | F | F | S | S | A | L | E | T | L | P | G | R | E | F | I | F | A | N | L | D |
Template Known Secondary structure |   |
 | . | . | . |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
| T | T | T |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |  | T |  |  |
Template Predicted Secondary structure |   |
 | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
665 | |
|
|
. | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . |
  |