|   |
21 | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | |
40 | . | . | |
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | |
|
|
|
. | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |
|  |  |  |  |  |  | . |  |
|
| . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | G | R | I | Y | K | T | G | M | P | R | S | N | Y | F | S | E | R | . |
C | K | G | . |
E | I | F | L | K | F | E | N | M | Q | R | T | G | S | F | K | I | R | G | A | F | N | K | L | S | S | L | T | D | . |
. |
. |
. |
A | E | K | R | K | G | V | V | A | C | S | A | G | N | H | A | Q | G | V | S | L | S | C |
Query Conservation |   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |   | . |   |
|   | . |   |
|   |   |
|   |
|   |   |
|
|
|
|
|   |
|   |
|   |
|   |   |   |
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|
|   |   |
|
|
|
|   |
|   |
|
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |
|   |   |
|   |
|
|   |   |   |
|
|   |
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |
|
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Sequence |   |
V | S | A | F | E | G | N | S | N | L | F | W | A | E | R | F | G | K | Q | F | L | G | X | N | D | L | W | V | K | H | C | G | I | S | H | T | G | S | F | K | D | L | G | X | T | V | L | V | S | Q | V | N | R | L | R | K | X | K | R | P | V | V | G | V | G | C | A | S | T | G | D | T | S | A | A | L | S | A | Y | C |
Template Known Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  | T | T | S | S | T | T | S | B | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
124 | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . |
  |
  |   |
95 | . | . | . | . | 100 | . | . | . | . | . | . | . | . | |
. | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | M | L | G | I | D | G | K | V | V | M | P | K | G | . |
A | P | K | S | K | V | A | A | T | C | D | Y | S | A | E | V | V | L | H | G | D | N | F | N | D | T | I | A | K | V | S | E | I | V | E | M | E | G | R | I | F | I | P | P | Y | D | D | P | K | V | I | A | G | Q | G | T | I | G | L | E | I | M | E | D | L |
Query Conservation |   |
  |   |   |
|   |   |   |   |
|
|   |
|   |   | . |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |   |   |
|   |   |
|   |
|   |
|
|   |   |
|   |   |
|   |   |   |   |
|
|   |
|
|   |
|   |
|   |
|
|
|
|   |   |   |
|
|   |   |   |   |
|   |
|   |   |   |   |
|
|   | . |
|
|   |
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|
Template Sequence |   |
A | S | A | G | I | P | S | I | V | F | L | P | A | N | K | I | S | X | A | Q | L | V | Q | P | I | A | N | G | A | F | V | L | S | I | D | T | D | F | D | G | C | X | K | L | I | R | E | I | T | A | E | L | P | I | Y | L | A | N | S | L | . |
N | S | L | R | L | E | G | Q | K | T | A | A | I | E | I | L | Q | Q | F |
Template Known Secondary structure |   |
 |  |  | T |
|
|  |  |  |  |  |  | G | G | G |
|
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  | G | G | G | S | . |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
204 | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | |
. | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . |
  |
  |   |
174 | . | |
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
| . | . |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | D | . |
. |
V | D | N | V | I | V | P | I | G | G | G | G | L | I | A | G | I | A | V | A | I | K | S | I | N | P | T | I | . |
. |
. |
. |
. |
R | V | I | G | V | Q | S | E | N | V | H | G | M | A | A | S | F | H | S | G | E | I | T | T | H | R | T | T | G | T | L | A | D | G | C | D | V | S | R | P | G | N | L |
Query Conservation |   |
  |   | . | . |   |
|   |
|
|   |   |   |
|
|
|
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   | . | . | . | . | . |
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |
|
|
|
|   |   |   |   |
|
|
|
|   |
|
|
|
|
|   |
|
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
D | W | Q | V | P | D | W | V | I | V | P | G | G | N | L | G | N | I | Y | A | F | Y | K | G | F | K | C | Q | E | L | G | L | V | D | R | I | P | R | X | V | C | A | Q | A | A | N | A | N | P | L | Y | L | H | Y | K | S | G | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | D | F | K | P | V | S | I | D | R |
Template Known Secondary structure |   |
T | S |
|
|
| S |  |  |  |  |  |
| S | S | T |  |  |  |  |  |  |  |  |  |  |
|
| T | T | T | T | S | S | S |
|
|
|  |  |  |  |  |  |  | T | T | S | S | T |  |  |  |  |  |  | T | T | T | . | . | . | . | . | . | . | . | . | . | . | . | T | T |
|
|
|
|
|
|  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
283 | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 350 |
  |
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
. | . | . | . | . | . | . | . | 310 | . | . | |
. | . | . | . | . | . | . | 320 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|  |  |  |  |  |
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | Y | E | I | V | R | E | L | V | D | D | I | V | L | V | S | E | D | E | I | R | N | S | M | I | A | L | I | Q | R | N | K | V | V | T | E | G | A | G | A | L | A | C | A | A | L | L | S | G | K | L | D | Q | Y | I | . |
Q | N | R | K | T | V | S | I | I | S | G | . |
G | N | I | D | L | S | R | V | S | Q | I | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|
|   |   |   |
|
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |
|
|   |
|
|
|
| . |
|   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|   |   |
|   |
|   |
|
|   |
|
|
|
|
|
|   |   |
|   |   |
|   |   |   | . |
|
|
|   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |
Template Sequence |   |
A | V | Y | A | L | K | K | C | N | G | I | V | E | E | A | T | E | E | E | L | X | D | A | X | A | Q | A | D | S | . |
T | G | X | F | I | C | P | H | T | G | V | A | L | T | A | L | F | K | L | R | N | Q | G | V | I | A | P | T | D | R | T | V | V | V | S | T | A | H | G | L | K | F | T | Q | S | K | I | D | Y | H |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
| T | T |
|
|  |  |  |  |  |
| B |
| G | G | G | G |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
368 | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | |
. | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . |
  |
  |   |
325 |
Predicted Secondary structure |   |
|
Query SS confidence |   |
|
Query Sequence |   |
G |
Query Conservation |   |
  |
Alig confidence |   |
|
Template Conservation |   |
  |
Template Sequence |   |
S |
Template Known Secondary structure |   |
T |
Template Predicted Secondary structure |   |
 |
Template SS confidence |   |
|
  |   |
447 |
  |