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Job DescriptionP23893
Confidence99.95%DateThu Jan 5 11:40:26 GMT 2012
Rank73Aligned Residues346
% Identity15%Templatec3e9kA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   47..50.........60.........70.........80...... ...90.........100.... .....110......
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Query Sequence  VDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFG. . . . . . . . . APTEMEVKMAQLVTELVP. TMDMVRMVNSGT
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Template Sequence  NKDENAIYFLGN. . . . SLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALT
Template Known Secondary structure 
TT
B

BTT....TS

B
TTGGGGGTSSSS
GGGTTGGGT

GGG
S
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   63......70.... .....80.........90.........100.........110.........120.........130........
 
   117..120......... 130.........140.........150.........160.........170.........180.........190.....
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Query Sequence  EATMSAIRLARGF. TGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKYTLTCTYNDLASVRAAFEQYP
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Template Sequence  VNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETL. . . . . . RIEDILEVIEKEG
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SSS
TT

TT




TT
SS
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G
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   139140.........150.........160.........170.........180.........190......... 200.........210..
 
   196...200.........210.........220.........230.........240.........250.........260....... ..270....
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Query Sequence  QEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKII. GGGMPVG
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Template Sequence  DSIAVILFSGVHFYTGQHFN. . . . IPAITKAGQAKGCYVGFDLAHAVGNVELYL. . HDWGVDFACWCSYKYLNAGAGGIA
Template Known Secondary structure  GGSB
TTT
BB

....TT

TTTTTTS


..T


SSSTT


TT


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   213......220.........230.. .......240.........250.........260.. .......270.........280......
 
   275....280.........290....... ..300.........310.........320.........330...
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Query Sequence  AFGGRRDVMDALAPTGPVYQAGT. . . . . . . . . . . . . . . . . . . . . LSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAE
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Template Sequence  GAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTG
Template Known Secondary structure 
GGGTTTS

SS

GGGB
TT

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B
SSGGGG

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   287..290.........300.........310.........320.........330.........340.........350.........360......
 
   334.....340.........350 .........360.........370.........380.........390.........400.......
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Query Sequence  GLLEAAEEAGIPLVVNH. . . . . . VGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEAGFMSVAH
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Template Sequence  YLEYLIKHNYGVVNIITPSHVEERGCQLTITFSVPNK. . . . . . . . . . . . . . . . DVFQELEKRGVVCDKRNPNGIRVAPVP
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S
SSGGGB
S


TT
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TTT
TTTB

T
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   367..370.........380.........390.........400... ......410.........420.........430
 
   408.410.........420....
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Query Sequence  . . . SMEDINNTIDAARRVFA
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Template Sequence  LYNSFHDVYKFTNLLTSILD
Template Known Secondary structure  TT

T
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   440.........450.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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