|   |
12 | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | Q | L | H | K | F | G | G | S | S | L | A | D | V | . |
K | C | Y | L | R | V | A | G | I | M | A | E | Y | S | Q | P | D | D | M | M | V | V | S | A | A | G | S | T | T | N | Q | L | I | N | W | L | K | L | S | Q | T | D | R | L | S | A | H | Q | V | Q | Q | T | L | R | R | Y | Q | C | D | L | I | S | G | L | L |
Query Conservation |   |
  |   |
|   |
|
|
|
|
|
|
|   |   |   | . |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
K | V | V | L | S | L | G | G | S | V | L | S | N | E | S | E | K | I | R | E | F | A | K | T | I | E | S | V | A | Q | Q | N | Q | V | F | V | V | V | G | G | G | K | L | A | R | E | Y | I | K | S | A | R | E | L | G | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| S | S | T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
91 | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | A | E | E | A | D | S | L | I | S | A | F | V | S | D | L | E | R | L | A | A | L | L | D | S | G | I | N | D | A | V | Y | A | E | V | V | G | H | G | E | V | W | S | A | R | L | M | S | A | V | L | N | Q | Q | G | L | P | A | A | W | L | D | A | R | E | F | L | R | A | E | R | A | A | Q | P | Q | V | D | E | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|   |   |
|
|   |
|
|
|   |   |
|   |   |   |
|
|   |
|   |   |
|
|   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | E | T | F | C | D | Y | I | G | I | A | A | T | R | L | N | A | M | L | L | I | S | A | I | P | S | A | A | K | K | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | B |
| S | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
58 | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
  |
  |   |
171 | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | S | Y | P | L | L | Q | Q | L | L | V | Q | H | P | G | K | R | L | V | V | T | G | F | I | S | R | N | N | A | G | E | T | V | L | L | G | R | N | G | S | D | Y | S | A | T | Q | I | G | A | L | A | G | V | S | R | V | T | I | W | S | D | V | A | G | V | Y | S | A | D | P | R | K | V | K | D | A | C | L | L | P |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|
|   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |
|   |   |
|   |
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
| . | . |   |   |   |   |
|
|
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|
|   |   |
|
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |
|
|   |
|   |
Template Sequence |   |
V | D | F | M | E | A | E | E | L | S | . |
. |
K | L | Y | R | V | V | V | M | G | G | T | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | G | H | T | T | D | A | T | A | A | L | L | A | E | F | I | K | A | D | V | F | I | N | A | T | N | V | D | G | V | Y | S | A | D | P | K | S | D | T | S | A | V | K | Y | D |
Template Known Secondary structure |   |
S | S |  |  |  |  |  |  |  |  | . | . | T | T |
| S |  |  |  |  |
|
|
| S | . | . | . | . | . | . | . | . | . | . | . | S | S | S |
| T |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  | S | S | S | S |
| B |
| S | S |
| S | S | S | S | S |
|
| B |
| S |
Template Predicted Secondary structure |   |
 |
|  |  |  |  |  |  |  |  | . | . |  |
|
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
90 | . | . | . | . | . | . | . | . | . | |
|
100 | . | . | . | . | . | . | . | . | . | 110 | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . |
  |
  |   |
251 | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | 290 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | R | L | D | E | A | S | E | L | A | R | L | A | A | P | . |
V | L | H | A | R | T | L | Q | P | V | S | G | S | E | I | D | L | Q | L | R | C | S | . |
. |
. |
. |
. |
. |
. |
. |
Y | T | P | D | Q | G | S | T | R | I | E |
Query Conservation |   |
  |
|
|
|   |
|
|   |
|
|
|   |   |
|
|
| . |
|
|
|
|
|
|
|   |
|
|   |   |   |   |
|
|
|   |
|   |
|
| . | . | . | . | . | . | . | . |   |   |
|   |   |   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |
|
|   |   |
|
|   |
|
|
Template Sequence |   |
R | L | S | P | Q | Q | L | V | E | I | V | S | R | G | T | N | V | V | I | D | L | L | A | A | K | I | I | E | R | S | K | I | K | T | Y | V | I | L | G | T | P | E | N | I | M | K | A | V | K | G | E | A | V | G | T | V | I | A |
Template Known Secondary structure |   |
 |  |
|  |  |  |  |  |  |  | T |
|
|
|
|
|
|
| S |
|  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | T | T |
|
|
| S |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
157 | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . |
  |