|   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
|
. | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
. | . | . | . | . | . | . | . | . | 60 | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 70 |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  | . |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | L | T | G | T | G | G | A | Q | G | V | P | A | W | G | C | E | C | A | A | C | A | R | A | R | R | . |
. |
S | P | Q | Y | R | R | Q | P | C | S | G | V | V | K | F | N | D | A | I | . |
T | L | I | D | A | G | L | H | D | L | A | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | W | S | P | G | S | F | Q |
Query Conservation |   |
|   |   |
|
|
|
|   |   |   |
|   |
|   |   |   |
|   |
|   |   |
|   |   |   |   |   | . | . |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   | . |
|
|
|
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|
|
|   |   |   |
|   |
|   |   |   |
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|
Template Sequence |   |
I | Q | V | L | G | S | A | A | G | G | G | F | P | Q | W | N | C | N | C | V | N | C | K | G | Y | R | D | G | T | L | K | A | T | A | R | T | Q | S | S | I | A | L | S | D | D | G | V | H | W | I | L | C | N | A | S | P | D | I | R | A | Q | L | Q | A | F | A | P | X | Q | P | A | R | A | L | R | D | T | G | I | N |
Template Known Secondary structure |   |
 |  |  |  |  |
| B |
| T | T |
| B | S |
| T | T |
|
| S |  |  |  |  |  |  |  | T | T |
| S |
|
|
|
| B |
| B |
|  |  |  |  |  | S | S | S | S | S |  |  |  |  | S |
|
| T | T |  |  |  |  |  |  | T |
| G | G | G |
|
|
| S | S | S | S |
|
| S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . |
  |
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | F | L | L | T | H | Y | H | M | D | H | V | Q | G | L | F | P | L | R | W | G | V | G | D | P | I | P | V | Y | G | P | P | D | E | Q | G | C | D | D | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | K | H | P | G | L | L | D | F | S | H | T | V | E | P | F | V | V | F | D | L | Q | G | L | Q | V | T | P | L | P |
Query Conservation |   |
|
|
|
|
|
|   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
|   |
|   |
|
|   |   |
|
|   |   |
| . | . |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
A | I | V | L | L | D | S | Q | I | D | H | T | T | G | L | L | S | L | . |
. |
R | E | G | C | P | H | Q | V | W | C | T | D | X | V | H | Q | D | L | T | T | G | F | P | L | F | N | X | L | S | H | W | N | G | G | L | Q | W | N | R | I | E | L | E | G | S | F | V | I | D | A | C | P | N | L | K | F | T | P | F | P |
Template Known Secondary structure |   |
 |  |  |
| S |
|
|
|  |  |  |  | G | G | G | G | G | G | . | . | G | G | G |
|
|  |  |  |  |  |
|  |  |  |  |  |  | T | T | T | T | S |
|  |  |  |  |  | T | T | S | T | T |
|  |  |  |  |  |
|
| S | S | S |
| B |
|
| T | T |
| T | T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  | . | . |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | |
|
. | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
  |
  |   |
141 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
L | N | H | S | K | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | F | G | Y | L | L | E | T | A | H | S | R | V | A | W | L | S | D | T | A | G | L | P | E | K | T | L | K | F | L | R | N | N | Q | P | Q | V | M | V | M | D | C | S | H | P | P | R | A | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | R | S | A | A | P | P | Y | S | P | H | R | F | D | P | H | P | G | D | N | L | G | L | X | V | E | D | T | R | T | G | G | K | L | F | Y | A | P | G | L | G | Q | V | D | E | K | L | L | A | X | X | H | . |
. |
G | A | D | C | L | L | V | D | G | T | L | W | E | D | D | E | X | Q | R | R | G | V | G | T | R | T |
Template Known Secondary structure |   |
|
|
|
|
|
| T | T | S | T | T | T | T | S |
|
| T | T | S | S |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  | S |
|
| S |
|
|
|  |  |  |  |  |  |  | T | . | . | T |
| S |  |  |  |  |  |
|
|
| S | S | T | T |  |  |  |  |  | T | S |
| S |
|
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
196 | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . |
Predicted Secondary structure |   |
. | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
A | P | R | N | H | C | D | L | N | T | V | L | A | L | N | Q | V | I | R | S | P | R | V | I | L | T | H | I | S | H | Q | F | . |
. |
. |
. |
. |
D | A | W | L | M | E | N | A | L | P | S | G | F | E | V | G | F | D | G | M | E | I | G | V |
Query Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|   |
|   |
|
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|   |
|   |
|
Template Sequence |   |
G | R | E | X | G | H | L | A | Q | N | G | P | G | G | X | L | E | V | L | D | G | F | P | R | Q | R | K | V | L | I | H | I | N | N | T | N | P | I | L | D | E | N | S | P | E | R | A | E | V | L | R | R | G | V | E | V | A | F | D | G | X | S | I | E | L |
Template Known Secondary structure |   |
S | S | S | S | S |
|
|
| S | S | S | S | S | S |  |  |  |  | G | G | G |
|
| S | S |  |  |  |  |  | S | B |
| T | T |
| G | G | G | S | T | T |
|  |  |  |  |  |  |  |  | T | T |  |  |  |
|
| T | T |
|  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . |
  |