|   |
24 | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | |
|
|
|
|
. | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
N | D | D | E | L | F | R | L | L | D | D | H | N | S | L | K | R | I | S | S | A | R | V | L | Q | L | R | G | G | Q | D | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | R | L | A | I | E | F | C | S | D | K | N | Y | I | R | R | D | I | G | A | F | I | L | G | Q | I | . |
. |
. |
. |
. |
K | I | C | K | K | C |
Query Conservation |   |
  |
|
|   |
|   |   |   |
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |
| . | . | . | . | . |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | V | P | L | F | I | Q | L | L | Y | T | G | S | V | E | V | K | E | Q | A | I | W | A | L | G | N | V | A | G | D | S | T | D | Y | R | D | Y | V | L | Q | C | N | A | M | E | P | I | L | G | L | F | N | S | N | K | P | S | L | I | R | T | A | T | W | T | L | S | N | L | C | R | G | K | K | P | Q | P | D | W | S |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S | S |
|
|
|  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
  |
  |   |
88 | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | |
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
E | D | N | V | F | N | I | L | N | N | M | A | L | N | D | K | S | A | C | V | R | A | T | A | I | E | S | T | A | Q | R | C | K | K | N | P | . |
. |
. |
. |
. |
I | Y | S | P | K | I | V | E | Q | S | Q | I | T | A | F | D | K | S | T | N | V | R | R | A | T | A | F | A | I | S | V | I | N | D | K | A | T | . |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | V | S | Q | A | L | P | T | L | A | K | L | I | Y | S | M | D | T | E | T | L | V | D | A | C | W | A | I | S | Y | L | S | D | G | P | Q | E | A | I | Q | A | V | I | D | V | R | I | P | K | R | L | V | E | L | L | S | H | E | S | T | L | V | Q | T | P | A | L | R | A | V | G | N | I | V | T | G | N | D | L | Q |
Template Known Secondary structure |   |
 |  | G | G | G |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | G | G | G |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
254 | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | |
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | P | L | L | I | N | L | L | K | D | P | N | G | D | V | R | N | W | A | A | F | A | I | N | I | N | K | Y | D | N | S | D | I | R | D | C | F | V | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
M | L | Q | D | K | N | E | E | V | R | I | E | A | I | I | G | L | S | Y | R | K | . |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
Template Sequence |   |
T | Q | V | V | I | N | A | G | V | L | P | A | L | R | L | L | L | S | S | P | K | E | N | I | K | K | E | A | C | W | T | I | S | N | I | T | A | G | N | T | E | Q | I | Q | A | V | I | D | A | N | L | I | P | P | L | V | K | L | L | E | V | A | E | Y | K | T | K | K | E | A | C | W | A | I | S | N | A | S | S | G |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
334 | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | |
|
. | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | 250 | . | . | . | . | . | . | . | . | . | 260 | |
|
|
|
|
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | K | R | V | L | S | V | L | C | D | E | L | K | . |
. |
K | N | T | V | Y | D | D | I | I | E | A | A | G | E | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | D | K | T | L | L | P | V | L | D | T | M | . |
. |
. |
. |
. |
. |
. |
. |
L | Y | K | F | D |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   | . | . |
|   |   |
|
|   |   |
|   |   |
|
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
Template Sequence |   |
G | L | Q | R | P | D | I | I | R | Y | L | V | S | Q | G | C | I | K | P | L | C | D | L | L | E | I | A | D | N | R | I | I | E | V | T | L | D | A | L | E | N | I | L | K | M | G | E | A | D | K | E | A | R | G | L | N | I | N | E | N | A | D | F | I | E | K | A | G | G | M | E | K | I | F | N | C | Q | Q | N | E |
Template Known Secondary structure |   |
T | T | T |
| T |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
|  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  | G | G | G | G |
| S |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
414 | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . |
  |
  |   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | N | E | I | I | T | S | A | I | D | K | L | K | R |
Query Conservation |   |
|   |   |
|
|   |   |
|   |   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |
|   |   |
|
|   |   |
Template Sequence |   |
N | D | K | I | Y | E | K | A | Y | K | I | I | E | T |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
494 | . | . | . | . | . | 500 | . | . | . | . | . | . | . |
  |