|   |
1 | . | . | |
. | . | . | . | . | . | |
|
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  | . |  |  |  |
|
|
| . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
| . |
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | A | N | . |
R | M | I | L | N | E | . |
. |
T | A | W | F | G | R | G | A | V | G | A | L | T | D | E | V | K | R | R | G | Y | Q | K | A | L | I | V | T | D | K | T | L | V | Q | C | G | V | V | A | K | V | T | D | K | M | D | A | A | G | L | A | W | A | I | Y | D | G | V | V | P | N | P | T | I | T | V | V | K |
Query Conservation |   |
|   |   | . |   |
|   |   |
|   | . | . |   |
|   |   |
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |
|   |
|   |
|   |   |
|   |   |   | . | . | . | . | . |   |   |
|   |
|
|
|   |
|   |   |
|   | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
Template Sequence |   |
M | Q | R | L | E | V | R | E | P | V | P | Y | P | I | L | V | G | E | G | V | L | K | E | V | P | P | L | . |
. |
. |
. |
. |
A | G | P | A | A | L | L | F | D | R | R | V | E | . |
. |
G | F | A | Q | E | V | A | K | A | L | G | V | R | . |
. |
H | L | L | G | L | P | G | G | E | A | A | K | S | L | E | V | Y | G |
Template Known Secondary structure |   |
|  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  | S |
| G | G | G | G | S |
|
|
| . | . | . | . | . | S | S |
|  |  |  |  |  |  | G | G | G |  | . | . |  |  |  |  |  |  |  |  |  |  | T |
|
| . | . |
|  |  |  |  |
|
| S | G | G | G | S | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|  |  |  |  |  |
|  |  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 30 | . | . | . | . | . | . | . | . | . | 40 | |
|
. | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | |
|
|
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | |
|
. | . | . | . | . | . | . | . | . | 150 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | G | L | G | V | F | Q | N | S | G | A | D | . |
. |
. |
Y | L | I | A | I | G | G | G | S | P | Q | D | T | C | K | A | I | G | I | I | S | N | N | P | E | F | A | D | V | R | S | L | E | G | L | S | P | T | N | K | P | S | V | P | I | L | A | I | P | T | T | . |
. |
A | G | T | A | A | E | V | T | I | N | Y | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
| . | . | . |   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
| . | . |
|
|
|
|
|
|   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |
|   |
|   |
|
|
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
K | V | L | S | W | L | A | E | K | G | L | P | R | N | A | T | L | L | V | V | G | G | G | T | L | T | D | L | G | G | F | V | A | A | T | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | R | G | V | A | Y | L | A | F | P | T | T | T | L | A | I | V | D | A | S | V | G | G | K | T | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T |
|
| T | T |
|  |  |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |  | G | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G | G |
|
|  |  |  |  |  |  |
| S |  |  |  |  |  | T | T | T | S | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
72 | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . |
  |
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | T | D | E | E | K | R | R | K | F | V | C | V | D | P | H | D | I | P | Q | V | A | F | I | D | A | D | M | M | D | G | M | P | P | A | L | K | A | A | T | G | V | D | A | L | T | H | A | I | E | G | Y | I | T | R | G | A | W | A | L | T | . |
. |
. |
. |
. |
D | A | L | H | I | K | A | I | E | I | I | A | G | A |
Query Conservation |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . |
|   |   |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | N | L | P | E | G | K | N | L | V | G | A | F | H | F | . |
. |
. |
P | Q | G | V | Y | A | E | L | R | A | L | K | T | L | P | L | P | T | F | K | E | G | L | V | E | A | F | K | H | G | L | I | A | G | D | E | A | L | L | K | V | E | D | L | T | P | Q | S | P | R | L | E | A | F | L | A | R | A | V | A | V | K |
Template Known Secondary structure |   |
 |  |  | T | T |  |  |  |  |  |  |  |  |
|
| . | . | . |
| S |  |  |  |  |  | G | G | G | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| G | G | G | G |
|
| T | T |
|
| T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . |
|
|  |  |  |  |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
134 | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | |
|
|
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 |
  |
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
|
. | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
|
|
. | . | . | . | . | . | . | . | . | 300 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | G | S | V | A | G | D | K | D | A | G | E | E | M | A | L | G | Q | Y | V | A | G | M | G | F | S | N | V | G | L | G | L | V | H | G | M | A | H | P | L | G | A | F | . |
. |
Y | N | T | P | H | G | V | A | N | A | I | L | L | P | H | V | M | R | Y | . |
. |
. |
. |
N | A | D | F | T | G | E | K | Y | R | D |
Query Conservation |   |
|   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   | . | . |   |   |
|   |
|
|   |   |   |
|
|   |
|
|   |
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | R | V | T | E | E | D | P | L | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | G | K | R | R | L | L | N | L | G | H | T | L | G | H | A | L | E | A | Q | T | R | H | A | L | P | H | G | M | A | V | A | Y | G | L | L | Y | A | A | L | L | G | R | A | L | G | G | E | D | L | L | P | P | V | R | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| T | T | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S | G | G | G | G | G | G | T | T |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
211 | . | . | . | . | . | . | . | . | 220 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . |
  |
  |   |
302 | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | |
|
|
. | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | A | R | V | M | G | V | K | V | E | G | M | S | L | E | E | A | R | N | A | A | V | E | A | V | F | A | L | N | R | D | V | G | I | P | P | H | L | R | D | V | . |
. |
. |
G | V | R | K | E | D | I | P | A | L | A | Q | A | A | L | D | D |
Query Conservation |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|   |   |
|   |
|   | . | . | . |
|
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |
|   |
Template Sequence |   |
L | L | L | W | L | S | P | P | P | L | P | P | L | A | F | E | . |
. |
. |
. |
. |
. |
D | L | L | P | Y | L | S | L | H | W | V | V | P | L | A | P | G | R | L | V | V | R | P | L | P | E | G | L | L | R | E | A | F | A | A | W | R | E | E |
Template Known Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . |  |  | G | G | G |
|
|
|
|  |  |  |  |  |  | T | T |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
277 | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . |
  |