|   |
11 | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | D | R | D | C | L | I | V | G | G | G | D | V | A | E | R | K | A | R | L | L | L | D | A | G | A | R | L | T | V | N | A | L | A | F | I | P | Q | F | T | A | W | A | D | A | G | M | L | T | L | V | E | G | P | F | D | E | S | L | L | D | T | C | W | L | A | I | A | A | T | D | D | D | A | L | N | Q | R | V | S |
Query Conservation |   |
  |   |   |   |
|
|
|
|
|
|
|   |
|
|   |
|
|   |   |   |
|
|   |   |
|
|   |
|   |
|
|
|
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |
|   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|
|
|   |   |   |
|
|
|
|   |   |   |
|
|   |
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
K | Q | X | N | V | V | L | I | G | G | G | T | G | L | S | V | L | A | R | G | L | R | E | F | P | I | D | I | T | A | I | V | T | V | A | D | N | G | G | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |  |  |  |  |  |  |  |
|
|
|
|
| S |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
91 | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | A | E | A | R | R | I | F | C | N | V | V | D | A | P | K | A | A | S | F | I | M | P | S | I | I | D | R | S | P | L | M | V | A | V | S | S | G | G | T | S | P | V | L | A | R | L | L | R | E | K | L | E | S | L | L | P | L | H | L | G | Q | V | A | K | Y | A | G | Q | L | R | G | R | V | K | Q | Q | F | A |
Query Conservation |   |
  |   |
|   |   |   |   |   |
|
|
|   |   |
|   |
|   |   |   |
|
|   |   |
|
|   |
|   |   |
|   |
|   |
|
|
|
|
|   |
|   |
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|
|   |   |   |
|   |   |   |   |
|
|
|
|   |   |
|   |
|
|
|
| . | . | . | . | . | . | . | . | . |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | G | K | I | R | D | V | X | D | I | P | A | P | G | D | I | R | N | V | I | A | A | L | S | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
S |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  | T | S |
| . | . | . | . | . | . | . | . | . | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
42 | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. |
  |
  |   |
171 | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 210 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
T | M | G | E | R | R | R | F | W | E | K | L | F | V | N | D | R | L | A | Q | S | L | A | N | N | D | Q | K | A | I | T | E | T | T | E | Q | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | N | E | P |
Query Conservation |   |
  |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |
|   |   |
|
|
|   |
|   |
|   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |
|   |
|
|
|   |
|   |   |   |
|   |
|   |
|   |   |   |
|
|   |   |
|   |
|
|   |   |
|
Template Sequence |   |
E | S | I | L | T | Q | L | F | Q | Y | R | F | G | E | N | Q | V | D | G | H | S | L | G | N | L | V | I | A | G | X | T | N | I | T | N | D | F | G | H | A | I | K | E | L | S | K | V | L | N | I | K | G | Q | V | I | P | S | T | N | A | S | V | Q | L | N | A | V | X | E | D | G | E | I | V | H | G | E | T | N | I |
Template Known Secondary structure |   |
T | S |  |  |  |  |  |  | T |
| B |
|
| T | T | S | G | G | G |
| B |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |  |  |  |  | S |
| S | S |
|
|  |  |  |  |  |  | T | T | S |
|  |  |  | S | T | T | T | S |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
  |
  |   |
212 | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | |
. | . | . | . | . | . | |
|
|
|
. | . | 270 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|  |  |  |  | . | . | . | . |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | D | H | R | G | E | V | V | L | V | G | A | G | P | G | D | A | G | L | L | T | L | K | G | L | Q | Q | I | Q | Q | A | D | V | V | V | Y | D | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | V | S | D | D | I | M | N | L | V | R | R | . |
D | A | D | R | V | F | . |
. |
. |
. |
V | G | K | R | A | G | Y | H | C |
Query Conservation |   |
  |   |   |   |
|   |
|   |
|
|
|   |
|
|
|
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |
|
|
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|
|   |   |   |   |   | . |   |   |   |   |   |   | . | . | . | . |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   | . |   |   |
|   |   |
|   |
|
|   |   |
|
|   |
|
|   |
|
|
|
|   |   |
|
|
|   |
|   |
|
|
|   |
|
|   |
|
|
|   |   |
|   |
|   |
|
|   |
|   |
|
|   |
|
|
|
|
|
|   |
|
Template Sequence |   |
P | K | T | H | K | K | I | D | R | V | F | L | E | P | S | D | V | E | . |
P | X | N | E | A | I | E | A | L | E | Q | A | D | L | I | V | L | G | P | G | S | L | Y | T | S | V | I | S | N | L | C | V | K | G | I | S | E | A | L | L | R | T | S | A | P | K | L | Y | V | S | N | V | X | T | Q | P | G | E | T | D | N |
Template Known Secondary structure |   |
S | S | S |
| S |
|  |  |  |  |  |  |  | S |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |
| S | S |
|
|
|
|
|
|  |  |  |  | T | S |  |  |  |  |  |  |  |  |  |
|
| S |
|  |  |  |  |
|
| S | B |
|
| T | T | T |
| T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | |
. | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
  |
  |   |
277 | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | |
. | . | . | . | . | . | 300 | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | P | Q | E | E | I | N | Q | I | L | L | R | E | A | Q | K | G | . |
K | R | V | V | R | L | K | G | G | D | P |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
| . |   |   |
|
|   |
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|   |   |   |   |
Template Sequence |   |
Y | D | V | K | E | H | I | D | A | L | T | R | Q | V | G | E | P | F | I | D | F | V | I | C | S | S | E | S | Y |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
|
|
|  |  |  |
|
|
|
|
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
227 | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . |
  |