Return to main results Retrieve Phyre Job Id

Job DescriptionP45541
Confidence90.80%DateThu Jan 5 12:03:00 GMT 2012
Rank85Aligned Residues206
% Identity13%Templatec2cw6B_
PDB info PDB header:lyaseChain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria
Resolution2.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   17..20.........30.........40.........50 .........60.........70.......
Predicted Secondary structure 














...................












Query SS confidence 

































. . . . . . . . . . . . . . . . . . .


























Query Sequence  HAFRDASELGYDGIEIWGGRPHAFAPDLKAGGIK. . . . . . . . . . . . . . . . . . . QIKALAQTYQMPIIGYTPETNGYPYNM
Query Conservation    
      
   


                  ...................     
   

                
Alig confidence 

































...................

















.........
Template Conservation   
   
   

  



            
                         
  
   
   
 
  .........
Template Sequence  KLIDMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVLTPNLKGFEAAVAAGAKEVVIFG. . . . . . . . .
Template Known Secondary structure  TT
S




TTT
GGGTTS


TT
B



STT
S.........
Template Predicted Secondary structure 




















.........
Template SS confidence 















































































   58.60.........70.........80.........90.........100.........110.........120........
 
   78.80........ .90.........100.........110.........120.........130.........140... .....
Predicted Secondary structure 



........















.
Query SS confidence 










. . . . . . . .






















































.




Query Sequence  MLGDEHMRRES. . . . . . . . LDMIKLAMDMAKEMNAGYTLISAAHAGYLTPPNVIWGRLAENLSELCEYAENIGM. DLILE
Query Conservation             ........       
  
  

   
                       
  
   
   

. 
 

Alig confidence  .









........































....


















.




Template Conservation  .  
                      
  
   
  
              ....                 
 
 
 
 
Template Sequence  . AASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEG. . . . KISPAKVAEVTKKFYSMGCYEISLG
Template Known Secondary structure  .S
TSS
TTTTT
STT
BTTTB....S

TT
S
Template Predicted Secondary structure  .












....







Template SS confidence 















































































   129130.........140.........150.........160.........170........ .180.........190.........200...
 
   149150.........160.........170.........180.........190.........200.........210.........220........
Predicted Secondary structure 









































Query SS confidence 















































































Query Sequence  PLTPYESNVVCNANDVLHALALVPSPRLFSMVDICAPYVQAEPVMSYFDKLGDKLRHLHIVDSDGASDTHYIPGEGKMPL
Query Conservation                                  
                     
   

 
           
 
 

 
Alig confidence 



.....






































































Template Conservation 

 
.....   
  
  

  
    
 
 
  
 


 


 

 


  


  

 

 


     





   
Template Sequence  DTIG. . . . . VGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLAT
Template Known Secondary structure  TT
.....


S
GGGB
TTS
TT

BTTS



TTSSS


B
B
Template Predicted Secondary structure 



.....


































Template SS confidence 















































































   204... ..210.........220.........230.........240.........250.........260.........270........
 
   229230.........240.
Predicted Secondary structure 



Query SS confidence 












Query Sequence  RELMRDIIERGYE
Query Conservation        
   

 
Alig confidence 












Template Conservation 
 
   
   
  
Template Sequence  EDLVYMLEGLGIH
Template Known Secondary structure  TT
B
Template Predicted Secondary structure 



Template SS confidence 












   279280.........290.
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions