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Job DescriptionP25665
Confidence100.00%DateThu Jan 5 11:42:13 GMT 2012
Rank4Aligned Residues699
% Identity46%Templatec2nq5A_
PDB info PDB header:transferaseChain: A: PDB Molecule:5-methyltetrahydropteroyltriglutamate-- PDBTitle: crystal structure of methyltransferase from streptococcus2 mutans
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1........10.........20.........30.........40.........50.........60.........70.........80
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Query Sequence  MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNV
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Template Sequence  LT. KVSSLGYPRLGENREWKKLIEAYWAGKVSKNDLFAGAKELRLDFLKKQLNAGLDLIPVGDFSLYDHILDLSVQFNII
Template Known Secondary structure 

.B
S


SS
TT
TT
S
TT
SBS


SS
TT

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   1. .......10.........20.........30.........40.........50.........60.........70.........
 
   81........90.........100.........110.........120.........130.........140.........150.. .......
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Query Sequence  PARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALA. LGHKVKP
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Template Sequence  PKRFAKEPI. . DIDLYFAIARGN. . . . KENVASSMKKWFNTNYHYIVPEW. SKQRPKLNNNRLLDLYLEAREVVGDKAKP
Template Known Secondary structure 
GGGTTS
S..S

....SSS




TTSS


B
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S







GGG
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   80........ .90.........100 .........110.........120... ......130.........140.........150..
 
   160.........170.........180.........190.........200.........210.........220.........230.. ....
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Query Sequence  VLLGPVTWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDAL. . . QGQV
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Template Sequence  VITGPITYVALST. . . GVEDFTAAVKSLLPLYKQVFTELVKAGASYIQVDEPIFVTDEGKDYLQAAKAVYAYFAKEVPDA
Template Known Secondary structure 
T
B...S
S
TT


GGGGSSGGGGGSTT
Template Predicted Secondary structure 


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   153......160..... ....170.........180.........190.........200.........210.........220.........
 
   237..240.........250.........260.........270....... ..280.........290.........300.........310... .
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Query Sequence  KLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELH. KRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVG. K
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Template Sequence  KFIFQTYFEGLIDS. QVLSQLPVDAFGLDFVYGLEENLEAIKTGAFKGKEIFAGVIDGRNIWSSDFVKTSALLETIEEQS
Template Known Secondary structure 

SS

TT.TTSS
SSSSSTTTTTTS
TTS
B


TS
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   230.........240... ......250.........260.........270.........280.........290.........300........
 
   315....320.........330.........340.........350.........360.........370.........380.........390....
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Query Sequence  RDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEK
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Template Sequence  AALTIQPSCSLLHVPVTTKNETDLDPVLRNGLAFADEKLTEVKRLAEHLDGREDPAYDLHIAHFDALQAA. . . . . DFRNV
Template Known Secondary structure  SSS
GGGS
S
STT
TTS
TTB

TT


T
.....GGGS
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   309310.........320.........330.........340.........350.........360.........370........ .380...
 
   395....400.........410.........420.........430.........440.........450.........460.........470....
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Query Sequence  RLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQER
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Template Sequence  KLEDLSRVATKRPSDFAKRRDIQQEKLHLPLLPTTTIGSFPQD. . . . . . . . . . . . . . . . . AEYKQFIQAEIERWIRIQED
Template Known Secondary structure 



GGGS
SS
SS



SS
BB

SB



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   384.....390.........400.........410.........420...... ...430.........440......
 
   475....480.........490.........500.........510.........520.........530.........540.........550....
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Query Sequence  LGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTG
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Template Sequence  LDLDVLVHGEFERVDMVEFFGQKLAGFTTTKFGWVQSYGSRAVKPPIIYGDVQHLEPITVEETVYAQSLTDRPVKGMLTG
Template Known Secondary structure  T
SBB

B
TT
S
TTTT

SS

TT



S
SST
SS
B
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   464.....470.........480.........490.........500.........510.........520.........530.........540...
 
   555....560.........570.........580.........590.........600.........610.........620.........630....
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Query Sequence  PVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKD
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Template Sequence  PITITNWSFERTDIPRDQLFNQIGLAIKDEIKLLENAGIAIIQVDEAALREGLPLRKSKQKAYLDDAVHAFHIATSSVKD
Template Known Secondary structure  SB

SSS
TT



S
SSSSS
T
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   544.....550.........560.........570.........580.........590.........600.........610.........620...
 
   635....640.........650.........660.........670.........680.........690.........700.........710....
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Query Sequence  DTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKR
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Template Sequence  ETQIHTHMCYSKFDEIIDAIRALDADVISIL. . . . . . . . . . . . . . . . . . . GIGLGVYDIHSPRVPTKEEVVANIERPLRQ
Template Known Secondary structure  TS

S

STT

S

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S
TTSS



GGGGS
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   624.....630.........640.........650.... .....660.........670.........680....
 
   715....720.........730.........740.........750..
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Query Sequence  IPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRR
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Template Sequence  LSPTQFWVNPDCGLKTRQEPETIAALKVLVAATKEVRQ
Template Known Secondary structure  S
GGG
SS

TTS
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   704.....710.........720.........730.........740.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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