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Job DescriptionP25665
Confidence100.00%DateThu Jan 5 11:42:13 GMT 2012
Rank1Aligned Residues725
% Identity42%Templatec1t7lA_
PDB info PDB header:transferaseChain: A: PDB Molecule:5-methyltetrahydropteroyltriglutamate-- PDBTitle: crystal structure of cobalamin-independent methionine2 synthase from t. maritima
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1........10.........20.........30.........40.........50.........60.........70.........80
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Query Sequence  MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNV
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Template Sequence  FT. KAYAFGFPKIGEKREFKKALEDFWKGKITEEQFEEEMNK. LRMYMVENYRKNVDVIPSNELSYYDFVLDTAVMVGAV
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   81........90.........100.........110.........120.........130.........140.........150.........160
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Query Sequence  PARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPV
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Template Sequence  PERFGEYRG. . . LSTYFDMARGGK. . . . . . . ALEMTKFFNTNYHYLVPEIETE. EFYLLENKPLEDYLFFKSKGIETAPW
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GGG
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B


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   78.80...... ...90........ .100.........110.........120 .........130.........140......
 
   161........170.. .......180.........190.........200.........210.........220.........230......
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Query Sequence  LLGPVTWLWLGK. . . . VKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQV
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Template Sequence  VIGPFTFLYLSKRNGEWIRRPNQMEKLLESLVSVYKEVFEKLVENGCKEILVNEPAFVCDLEKAHWDLILNVYREL. SEF
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T
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GGGGS


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   147..150.........160.........170.........180.........190.........200.........210.........220.. ...
 
   237..240.........250.........260.........270........ .280.........290.........300.........310.....
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Query Sequence  KLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHK. RLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKR
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Template Sequence  PLTVFTYYDSV. SDYEACVSLPVKRLHFDFVSNEENLKNLEKHGFPEDKKLVAGVINGRQPWKVDLRKVASLVEKL. . . G
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   226...230...... ...240.........250.........260.........270.........280.........290.........300 .
 
   316...320.........330.........340.........350.........360.........370.........380.........390.....
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Query Sequence  DLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKR
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Template Sequence  ASAISNSCPLFHLPVTLELENNLPGGLKEKLAFAKEKLEELKMLKDFLEGKTFDLP. . . . . . . . NVSFEDFAVDLQAVER
Template Known Secondary structure 
SSS
GGGS
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SSSTTTGGGB

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   302.......310.........320.........330.........340.........350....... ..360.........370...
 
   396...400.........410.........420.........430.........440.........450.........460.........470.....
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Query Sequence  LAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQERL
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Template Sequence  VRNLPEDSFRREKEYTERDRIQRERLNLPLFPTTTIGSFPQTPEVRKMRSKYRKGEISKEEYEAFIKEQIKKAIELQEEI
Template Known Secondary structure  T

GGGTS
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   374.....380.........390.........400.........410.........420.........430.........440.........450...
 
   476...480.........490.........500.........510.........520.........530.........540.........550.....
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Query Sequence  GLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGP
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Template Sequence  GLDVLVHGEFERTDMVEFFAEKLNGIATTQNGWVLSYGSRCYRPPIIYGTVTRPEPMTLKEITYAQSLTEKPVKGMLTGP
Template Known Secondary structure  T
SSB



TT
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   454.....460.........470.........480.........490.........500.........510.........520.........530...
 
   556...560.........570.........580.........590.........600.........610.........620.........630.....
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Query Sequence  VTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDD
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Template Sequence  VTIMSWSYYREDIPEREIAYQIALAINEEVKDLEEAGIKIVQIDEPAFREKAPIKKSKWPEYFEWAINAFNLAANARP. E
Template Known Secondary structure  TS
SSS
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SSGGGT


T.T
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   534.....540.........550.........560.........570.........580.........590.........600.........610. .
 
   636...640.........650.........660.........670.........680.. .......690.........700.........710....
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Query Sequence  TQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDY. PNEIGPGVYDIHSPNVPSVEWIEALLKKAAKR
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Template Sequence  TQIHAHMCYSDFNEIIEYIHQLEFDVISIEASRSKGEIISAFENFKGWIKQIGVGVWDIHSPAVPSINEMREIVERVLRV
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S

TTTTTS

S
TTTTTGGGTSTT

S
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   613......620.........630.........640.........650.........660.........670.........680.........690..
 
   715....720.........730.........740.........750..
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Query Sequence  IPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRR
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Template Sequence  LPKELIWINPDCGLKTRNWDEVIPSLRNMVALAKEMRE
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GGG
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   693......700.........710.........720.........730
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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