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Job DescriptionP04079
Confidence100.00%DateThu Jan 5 10:58:10 GMT 2012
Rank2Aligned Residues504
% Identity41%Templatec2vxoB_
PDB info PDB header:ligaseChain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: human gmp synthetase in complex with xmp
Resolution2.5 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   910.........20.........30.........40.........50.........60.........70.........80........
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Query Sequence  RILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYG
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Template Sequence  AVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYG
Template Known Secondary structure 
SSSSTT

TT

T
S

S

TTSTT




GGGGTSSS
T
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   27..30.........40.........50.........60.........70.........80.........90.........100......
 
   8990.........100.........110.........120.........130.........140.........150.........160........
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Query Sequence  MQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFITVASTESCPFAIM
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Template Sequence  MQMMNKVFGGTVHK. . . KSDGVFNISVDNTCSLFRGLQKEE. . . . . . . . VVLLTHGDSVDKVADGFKVVARSGNI. VAGI
Template Known Secondary structure  TT

B
S...




TTSGGGTT

S........B

S

BSS

TT
TT.
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   107..110.........120 .........130.........140.... .....150.........160.........170 ....
 
   169170.........180.........190.........200.........210.........220.........230.........240........
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Query Sequence  ANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLH
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Template Sequence  ANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVLVLLSGGVDSTVCTALLN
Template Known Secondary structure  TTTTSB
TTSTTSTTTTTT






TT


SS
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   178.180.........190.........200.........210.........220.........230.........240.........250.......
 
   249250.. .......260.........270.........280.........290...... ...300.........310.......
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Query Sequence  RAIG. KNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLS. . . . . . . . . . ALAGENDPEAKRKIIGRVFVE
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Template Sequence  RALNQEQVIAVHIDNGFMRKRESQSVEE. ALKKLGIQVKVINAAHSFYNGTTTLPRISKTLNMTTSPEEKRKIIGDTFVK
Template Known Secondary structure  S
TTT
S


TTTTT.TT


T


B


B


GGG


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   258.260.........270.........280..... ....290.........300.........310.........320.........330......
 
   318.320....... ..330.........340....... ..350.........360........ .370.........380.........390.
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Query Sequence  VFDEEALKLE. . . DVKWLAQGTIYPDVIESAAS. ATGKAHVIKSHHNVGGLPKEM. . KMGLVEPLKELFKDEVRKIGLEL
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Template Sequence  IANEVIGEMNLKPEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGREL
Template Known Secondary structure  TT

GGG


SS

SS

S


GGGS

SS
TT

GGGGS
T
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   347..350.........360.........370.........380.........390.........400.........410.........420......
 
   392.......400.........410.........420.. .......430.........440......
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Query Sequence  GLPYDMLYRHPFPGPGLGVRVLGEVKKEYCD. . . . . . . . . . . . . . . . . . . . . . . . . LLRRADAIFIEELRKADLYDKVSQ
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Template Sequence  GLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHS
Template Known Secondary structure  T

T




TTGGGGGB

BSS



TTTS

S
S
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   427..430.........440.........450.........460.........470.........480.........490.........500......
 
   447..450.........460.........
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Query Sequence  AFTVFLPVRSVGVMGDGRKYDWV. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  LNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLS
Template Known Secondary structure  TTSS



TT
SS

SS

SS


B
S
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   507..510.........520.........530.........540.........550.........560.........570.........580......
 
   470.........480.........490.........500.
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . VSLRAVETIDFMTAHWAHLPYDFLGRVSNRII
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Template Sequence  TLRQADFEAHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVEVVLKMV
Template Known Secondary structure  TT
GGGSSB








STT







BB
SSSSSBB


BTTTB
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   587..590.........600.........610.........620.........630.........640.........650.........660......
 
   502.. .....510.........520.....
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Query Sequence  NEV. . . NGISRVVYDISGKPPATIEWE
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Template Conservation   

     
  
 

 
 


 




Template Sequence  TEIKKIPGISRIMYDLTSKPPGTTEWE
Template Known Secondary structure  TSTT


BTTS
SS

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   667..670.........680.........690...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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