|   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | |
. | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | Y | V | A | D | R | F | G | T | A | D | L | L | P | F | T | I | S | D | M | D | F | A | T | A | P | C | I | I | E | A | L | N | Q | R | L | M | H | G | V | F | G | Y | S | R | W | K | N | . |
D | E | F | L | A | A | I | A | H | W | F | S | T | Q | H | Y | T | A | I | D | S | Q | T | V | V | Y | G | P | S | V | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |
|   |
|
Template Sequence |   |
K | A | K | A | M | K | A | E | G | I | D | V | C | S | F | S | A | G | E | P | D | F | N | T | P | K | H | I | V | E | A | A | K | A | A | L | E | Q | G | K | T | R | Y | G | P | A | A | G | E | P | R | L | R | E | A | I | A | Q | K | L | Q | R | D | N | G | L | C | Y | G | A | D | N | I | L | V | T | N | G | G | K |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | T |
|
|
|  |  |
|
|
| S | S |
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| G | G | G |  |  |  |  | S |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
21 | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 |
  |
  |   |
98 | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | M | V | S | E | L | I | R | Q | W | S | E | T | G | E | G | V | V | I | H | T | P | A | Y | D | A | F | Y | K | A | I | E | G | N | Q | R | T | V | M | P | V | A | L | E | K | Q | A | D | G | W | F | C | D | M | G | K | L | E | A | V | L | A | K | P | E | C | K | I | M | L | L | C | S | P | Q | N | P | T | G | K |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
Template Sequence |   |
Q | S | I | F | N | L | M | L | A | M | I | E | P | G | D | E | V | I | I | P | A | P | F | W | V | S | Y | P | E | M | V | K | L | A | E | G | T | P | V | I | L | P | T | T | V | E | . |
T | Q | F | K | V | S | P | E | Q | I | R | Q | A | I | . |
T | P | K | T | K | L | L | V | F | N | T | P | S | N | P | T | G | M |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  | S | S |
|
| T |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
|
| G | G | . | G | T | T |
|
|
|  |  |  |  |  |  |  |
| . |
| T | T |  |  |  |  |  |  |  | S | S |
| T | T | T |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
101 | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | |
. | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | |
. | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . |
  |
  |   |
178 | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
|
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | W | T | C | D | E | L | E | I | M | A | D | L | C | E | R | H | G | V | R | V | I | S | D | E | I | H | M | D | M | V | W | G | E | Q | P | H | I | P | W | S | N | . |
. |
. |
V | A | R | G | D | W | A | L | L | T | S | G | S | K | S | F | N | I | P | A | L | T | G | A | Y | G | I | I | E | N | S | S | S | R | D |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | Y | T | P | D | E | V | R | A | I | A | Q | V | A | V | E | A | G | L | W | V | L | S | D | E | I | Y | E | K | I | L | Y | D | D | A | Q | H | L | S | I | G | A | A | S | P | E | A | Y | E | R | S | V | V | C | S | G | F | A | K | T | Y | A | M | T | G | W | R | V | G | F | L | A | G | P | V | P | L | V | K | A |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
| T | T | T | T |
| B |
| T | T |
|
|
|
|
| G | G | G | S |
|  |  |  |  |  | T |  |  |  |  |  |  | S | T | T | T | T | T |
| T | T | T |
|
|  |  |  |  |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
179 | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
  |
  |   |
255 | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Y | L | S | A | L | K | G | R | D | G | L | S | S | P | S | V | L | A | L | T | A | H | I | A | A | Y | Q | Q | G | A | P | W | L | D | A | L | R | I | Y | L | K | D | N | L | T | Y | I | A | D | K | M | N | A | A | F | P | E | L | N | W | Q | I | P | Q | S | T | Y | L | A | W | L | D | L | R | P | L | N | I | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
A | T | K | I | Q | G | . |
. |
. |
H | S | T | S | N | V | C | T | F | A | Q | Y | G | A | I | A | A | Y | E | N | S | Q | D | C | V | Q | E | M | L | A | A | F | A | E | R | R | R | Y | M | L | D | A | L | N | A | M | . |
P | G | L | E | C | P | K | P | D | G | A | F | Y | M | F | P | S | I | A | K | T | G | R | S |
Template Known Secondary structure |   |
 |  |  |  |  |  | . | . | . | T | T | T |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| . | T | T |
| B |
|
|
|
|
| B | T | T |  |  |
|
| B |
| G | G | G | T |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
259 | 260 | . | . | . | . | |
|
|
. | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | |
. | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
  |
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | N | A | L | Q | K | A | L | I | E | Q | E | K | V | A | I | M | P | G | Y | T | Y | G | E | E | G | R | G | F | V | R | L | N | A | G | C | P | R | S | K | L | E | K | G | V | A | G | L | I | N | A | I | R | A | V |
Query Conservation |   |
  |   |   |
|   |   |   |
|
|   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |
|   |
|   |   |   |
|   |
|
|   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |
|
|   |   |   |
|
|   |
|   |
|
|   |   |
|   |   | . | . |   |   |   |   |
|
|
|   |   |   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |   |
|   |   |
|
Template Sequence |   |
S | L | D | F | C | S | E | L | L | D | Q | H | Q | V | A | T | V | P | G | A | A | F | G | A | . |
. |
D | D | C | I | R | L | S | Y | A | T | D | L | D | T | I | K | R | G | M | E | R | L | E | K | F | L | H | G | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|  |  | G | G | G | G | T |
| . | . | T | T | B |  |  |  |  |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | |
|
. | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . |
  |