Secondary structure and disorder prediction

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Sequence		M	T	L	A	Q	F	A	M	I	F	W	H	D	L	A	A	P	I	L	A	G	I	I	T	A	A	I	V	S	W	W	R	N	R	K
Secondary structure
SS confidence
Disorder		?	?																															?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2hg5 chain D Region: 18 - 35 Aligned: 18 Modelled: 18 Confidence: 10.7% Identity: 11% PDB header:membrane protein Chain: D: PDB Molecule:kcsa channel; PDBTitle: cs+ complex of a k channel with an amide to ester substitution in the2 selectivity filter Phyre2 PDB 1no7 chain A Region: 18 - 34 Aligned: 17 Modelled: 17 Confidence: 9.7% Identity: 35% Fold: Major capsid protein VP5 Superfamily: Major capsid protein VP5 Family: Major capsid protein VP5 Phyre2 PDB 1no7 chain A Region: 18 - 34 Aligned: 17 Modelled: 17 Confidence: 9.7% Identity: 35% PDB header:viral protein Chain: A: PDB Molecule:major capsid protein; PDBTitle: structure of the large protease resistant upper domain of2 vp5, the major capsid protein of herpes simplex virus-1 Phyre2 PDB 3im4 chain C Region: 13 - 29 Aligned: 17 Modelled: 17 Confidence: 6.7% Identity: 47% PDB header:structural protein, signaling protein Chain: C: PDB Molecule:dual specificity a kinase-anchoring protein 2; PDBTitle: crystal structure of camp-dependent protein kinase a2 regulatory subunit i alpha in complex with dual-specific a-3 kinase anchoring protein 2 Phyre2 PDB 3t41 chain B Region: 14 - 27 Aligned: 14 Modelled: 14 Confidence: 5.6% Identity: 36% PDB header:hydrolase Chain: B: PDB Molecule:epidermin leader peptide processing serine protease epip; PDBTitle: 1.95 angstrom resolution crystal structure of epidermin leader peptide2 processing serine protease (epip) s393a mutant from staphylococcus3 aureus Phyre2 PDB 1r0r chain E Region: 14 - 27 Aligned: 14 Modelled: 14 Confidence: 5.5% Identity: 29% Fold: Subtilisin-like Superfamily: Subtilisin-like Family: Subtilases Phyre2 1 c2hg5D_ 2 d1no7a_ 3 c1no7A_ 4 c3im4C_ 5 c3t41B_ 6 d1r0re_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2hg5D_ 10.7 11 PDB header:membrane protein Chain: D: PDB Molecule:kcsa channel; PDBTitle: cs+ complex of a k channel with an amide to ester substitution in the2 selectivity filter 2 d1no7a_ 9.7 35 Fold:Major capsid protein VP5 Superfamily:Major capsid protein VP5 Family:Major capsid protein VP5 3 c1no7A_ 9.7 35 PDB header:viral protein Chain: A: PDB Molecule:major capsid protein; PDBTitle: structure of the large protease resistant upper domain of2 vp5, the major capsid protein of herpes simplex virus-1 4 c3im4C_ 6.7 47 PDB header:structural protein, signaling protein Chain: C: PDB Molecule:dual specificity a kinase-anchoring protein 2; PDBTitle: crystal structure of camp-dependent protein kinase a2 regulatory subunit i alpha in complex with dual-specific a-3 kinase anchoring protein 2 5 c3t41B_ 5.6 36 PDB header:hydrolase Chain: B: PDB Molecule:epidermin leader peptide processing serine protease epip; PDBTitle: 1.95 angstrom resolution crystal structure of epidermin leader peptide2 processing serine protease (epip) s393a mutant from staphylococcus3 aureus 6 d1r0re_ 5.5 29 Fold:Subtilisin-like Superfamily:Subtilisin-like Family:Subtilases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0