Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.
Sequence		M	G	Y	D	S	R	L	D	H	L	A	A	T	S	W	Y	P	F	F	N	N	V	T	T	R	G	E	I	I	E	P	Y	S	L	T	L	D	E	A	C	Q	F	L	K	I	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																					?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1y6u chain A Region: 28 - 46 Aligned: 19 Modelled: 19 Confidence: 50.0% Identity: 42% PDB header:dna binding protein Chain: A: PDB Molecule:excisionase from transposon tn916; PDBTitle: the structure of the excisionase (xis) protein from2 conjugative transposon tn916 provides insights into the3 regulation of heterobivalent tyrosine recombinases Phyre2 PDB 2lcy chain A Region: 11 - 19 Aligned: 9 Modelled: 9 Confidence: 10.9% Identity: 33% PDB header:viral protein Chain: A: PDB Molecule:virion spike glycoprotein; PDBTitle: nmr structure of the complete internal fusion loop from ebolavirus gp22 at ph 5.5 Phyre2 PDB 2a5y chain B domain 3 Region: 6 - 43 Aligned: 38 Modelled: 38 Confidence: 9.1% Identity: 37% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Extended AAA-ATPase domain Phyre2 PDB 3l51 chain A Region: 19 - 32 Aligned: 14 Modelled: 14 Confidence: 9.0% Identity: 29% PDB header:cell cycle Chain: A: PDB Molecule:structural maintenance of chromosomes protein 2; PDBTitle: crystal structure of the mouse condensin hinge domain Phyre2 PDB 1f3u chain D Region: 12 - 39 Aligned: 21 Modelled: 28 Confidence: 7.9% Identity: 38% Fold: triple barrel Superfamily: Rap30/74 interaction domains Family: Rap30/74 interaction domains Phyre2 PDB 2j8q chain B Region: 13 - 42 Aligned: 30 Modelled: 30 Confidence: 7.1% Identity: 23% PDB header:nuclear protein Chain: B: PDB Molecule:cleavage and polyadenylation specificity factor 5; PDBTitle: crystal structure of human cleavage and polyadenylation2 specificity factor 5 (cpsf5) in complex with a sulphate3 ion. Phyre2 PDB 3s88 chain J Region: 11 - 19 Aligned: 9 Modelled: 9 Confidence: 6.8% Identity: 44% PDB header:immune system/viral protein Chain: J: PDB Molecule:envelope glycoprotein; PDBTitle: crystal structure of sudan ebolavirus glycoprotein (strain gulu) bound2 to 16f6 Phyre2 PDB 2w27 chain A Region: 14 - 40 Aligned: 27 Modelled: 27 Confidence: 6.2% Identity: 33% PDB header:signaling protein Chain: A: PDB Molecule:ykui protein; PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium Phyre2 1 c1y6uA_ 2 c2lcyA_ 3 d2a5yb3 4 c3l51A_ 5 d1f3ud_ 6 c2j8qB_ 7 c3s88J_ 8 c2w27A_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1y6uA_ 50.0 42 PDB header:dna binding protein Chain: A: PDB Molecule:excisionase from transposon tn916; PDBTitle: the structure of the excisionase (xis) protein from2 conjugative transposon tn916 provides insights into the3 regulation of heterobivalent tyrosine recombinases 2 c2lcyA_ 10.9 33 PDB header:viral protein Chain: A: PDB Molecule:virion spike glycoprotein; PDBTitle: nmr structure of the complete internal fusion loop from ebolavirus gp22 at ph 5.5 3 d2a5yb3 9.1 37 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 4 c3l51A_ 9.0 29 PDB header:cell cycle Chain: A: PDB Molecule:structural maintenance of chromosomes protein 2; PDBTitle: crystal structure of the mouse condensin hinge domain 5 d1f3ud_ 7.9 38 Fold:triple barrel Superfamily:Rap30/74 interaction domains Family:Rap30/74 interaction domains 6 c2j8qB_ 7.1 23 PDB header:nuclear protein Chain: B: PDB Molecule:cleavage and polyadenylation specificity factor 5; PDBTitle: crystal structure of human cleavage and polyadenylation2 specificity factor 5 (cpsf5) in complex with a sulphate3 ion. 7 c3s88J_ 6.8 44 PDB header:immune system/viral protein Chain: J: PDB Molecule:envelope glycoprotein; PDBTitle: crystal structure of sudan ebolavirus glycoprotein (strain gulu) bound2 to 16f6 8 c2w27A_ 6.2 33 PDB header:signaling protein Chain: A: PDB Molecule:ykui protein; PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0