Job Description P42640 Confidence 99.86% Date Thu Jan 5 12:02:01 GMT 2012 Rank 21 Aligned Residues 249 % Identity 16% Template c2xrgA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor Resolution 3.20 Å

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		212	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.		270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290
Predicted Secondary structure																																																												.
Query SS confidence																																																												.
Query Sequence		Y	F	Q	L	S	V	R	D	T	G	I	D	T	Y	V	L	I	V	G	E	S	V	R	V	D	N	M	S	L	Y	G	Y	T	R	S	T	T	P	Q	V	E	A	Q	R	K	Q	I	K	L	F	N	Q	A	I	S	G	A	P	.	Y	T	A	L	S	V	P	L	S	L	T	A	D	S	V	L	S	H	D	I	H
Query Conservation																																																												.
Alig confidence																																	.	.	.																									.
Template Conservation																																	.	.	.
Template Sequence		K	V	P	E	C	P	A	G	F	V	R	P	P	L	I	I	F	S	V	D	G	F	R	A	S	Y	M	K	K	G	S	.	.	.	K	V	M	P	N	I	E	K	L	R	S	C	G	T	H	A	P	Y	M	R	P	V	Y	P	T	K	T	F	P	N	L	Y	T	L	A	T	G	L	Y	P	E	S	H	G	I	V
Template Known Secondary structure			S					T	T		S	S										T			G	G	G	G	G	S		T	.	.	.	T	T	S										S				S						S	S		S												S						S
Template Predicted Secondary structure																																	.	.	.
Template SS confidence
		152	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.				.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.
		291	.																										.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.
Predicted Secondary structure				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		N	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	D	N	I	I	N	M	A	N	Q	A	G	F	Q	T	F	W	L	S	S	Q	S	A	F	R	Q	N	G	T	A	V	T	S	I	A	M	R	A	M	E	T	V	Y	V	R	G	F	D	E	L	L	L	P
Query Conservation				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		G	N	S	M	Y	D	P	V	F	D	A	S	F	H	L	R	G	R	E	K	F	N	H	R	W	W	G	G	Q	P	L	W	I	T	A	T	K	Q	G	V	R	A	G	T	F	F	W	S	V	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	P	H	E	R	R	I	L
Template Known Secondary structure			S	S				T	T	T	T					S	S	S	S	G	G	G		T	T	S			S									T	T	T			B							T	T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S
Template Predicted Secondary structure																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		229	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.																							.	280	.	.	.	.	.	.
		346	.	.	.	350	.	.	.		.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.					.	.	.	.	.	.	420
Predicted Secondary structure										.																																																													.	.	.	.
Query SS confidence										.																																																													.	.	.	.
Query Sequence		H	L	S	Q	A	L	Q	Q	.	N	T	Q	Q	K	K	L	I	V	L	H	L	N	G	S	H	E	P	A	C	S	A	Y	P	Q	S	S	A	V	F	Q	P	Q	D	D	Q	D	A	C	Y	D	N	S	I	H	Y	T	D	S	L	L	G	Q	V	F	E	L	L	K	D	.	.	.	.	R	R	A	S	V	M	Y
Query Conservation										.																																																													.	.	.	.
Alig confidence										.																													.	.	.	.	.	.	.	.	.	.	.																						.	.	.	.
Template Conservation																																							.	.	.	.	.	.	.	.	.	.	.
Template Sequence		T	I	L	Q	W	L	S	L	P	D	N	E	R	P	S	V	Y	A	F	Y	S	E	Q	P	D	F	S	G	H	K	Y	G	P	F	G	P	E	.	.	.	.	.	.	.	.	.	.	.	M	T	N	P	L	R	E	I	D	K	T	V	G	Q	L	M	D	G	L	K	Q	L	R	L	H	R	C	V	N	V	I	F
Template Known Secondary structure							T	T	S		T	T	T			S																		T	T		G	G	.	.	.	.	.	.	.	.	.	.	.	G																					T	T		T	T	T
Template Predicted Secondary structure																																							.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		287	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.												.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.
		421	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.
Predicted Secondary structure																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		F	A	D	H	G	L	E	R	D	P	T	K	K	N	V	Y	F	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		V	G	D	H	G	M	E	D	V	T	C	D	R	T	E	F	L	S	N	Y	L	T	N	V	D	D	I	T	L	V	P	G	T	L	G	R	I	R	A	K	Y	D	P	K	T	I	I	A	A	L	T	C	K	K	P	D	Q	H	F	K	P	Y	M	K	Q	H	L	P	K	R	L	H	Y	A	N	N	R	R	I	E
Template Known Secondary structure				S								S	S	S				G	G	G	T		S			T	T						B	S																T	T	S	S		S	T	T								G	G	G	S		G	G	G				S	S	T	T	S
Template Predicted Secondary structure
Template SS confidence
		356	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.
																						438	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	H	G	G	R	E	A	S	Q	Q	A	Y	H	V	P	M	F	I	W	Y	S	P	V	L	G	D	G	V	D	R	T	T	E	N	N	I	F	S	T	A	Y	N	N	Y	L	I	N	A	W	M	G	V	T	K	P	E	Q	P	Q	T	L
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.										.								.	.	.	.	.
Template Conservation																															.								.	.	.	.	.
Template Sequence		D	I	H	L	L	V	D	R	R	W	H	V	A	R	K	P	F	Q	G	D	H	G	F	D	N	K	V	N	S	.	M	Q	T	V	F	V	G	.	.	.	.	.	Y	G	P	T	F	K	Y	R	T	K	V	P	P	F	E	N	I	E	L	Y	N	V	M	C	D	L	L	G	L	K	P	A	P	N	N	G	T	H
Template Known Secondary structure		S							T	T					S									S		T	T		G	G	.	G		B					.	.	.	.	.		S	S	S	B		S	S		B						G	G	G										T					S		S	S		T
Template Predicted Secondary structure																															.								.	.	.	.	.
Template SS confidence
		442	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470		.	.	.	.	.	.	.						.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.
		498	.	500	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	E	V	I	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	S	L	N	H
Template Known Secondary structure		T	T	T	G	G
Template Predicted Secondary structure
Template SS confidence
		528	.	530	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions