|   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | P | A | A | W | Q | N | N | L | P | L | T | P | A | D | K | V | S | G | Y | N | N | F | Y | E | F | G | L | D | K | A | D | P | A | A | N | A | G | S | L | K | T | D | P | W | T | L | K | I | S | G | E | V | A | K | P | L | T | L | D | H | D | D | L | T | R | R | F | P | L | E | E | R | I | Y | R | M | R | C | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |
|   |
|   |
|
|
|   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|   |
|   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |
| . | . | . | . |
|
|
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |
|   |
|   |
|   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|
Template Sequence |   |
R | P | P | Q | L | E | T | P | F | S | V | F | D | E | G | L | I | T | P | N | D | A | F | F | . |
. |
. |
. |
V | R | Y | H | L | A | G | I | P | L | E | I | D | P | D | A | F | R | L | E | I | K | G | K | V | G | T | P | L | S | L | S | L | Q | D | L | K | N | D | F | P | A | S | E | V | V | A | V | N | Q | C | S |
Template Known Secondary structure |   |
T | T | T |  |  |  |
|
| G | G | G | G | G | S |
| S | S |
|
| G | G | G |
|
| . | . | . | . |  |  |
| S |
| S | B |
|
|
|
|
|
| T | T | T |
|
|  |  |  |  |  | S | B | S | S |
|  |  |  |
|  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
|
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . |
  |
  |   |
148 | . | 150 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 |
Predicted Secondary structure |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | M | V | V | P | W | I | G | F | P | L | H | K | L | L | A | L | A | E | P | T | S | N | A | K | Y | V | A | F | E | T | I | Y | A | P | E | Q | M | P | G | Q | Q | D | R | F | I | G | G | G | L | K | Y | P | Y | V | E | G | L | R | L |
Query Conservation |   |
  |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |
|   |
|
|   |
|   |
|
|
|   |   |
|
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |
|   |
|   |
|
|   |
|   |
|
|
|   |   |
|
|
|   |   |   |
|   |   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|
|
|
|
Template Sequence |   |
G | N | S | R | G | F | V | E | P | R | V | G | G | G | Q | L | A | N | G | A | M | G | N | A | R | W | R | G | V | P | L | K | A | V | L | E | K | A | G | V | Q | A | G | A | K | Q | V | T | F | G | G | L | D | G | P | V | I | P | E | T | P | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | V | K | A | L | S | I |
Template Known Secondary structure |   |
T | T | T | G | G | G |
| S | S |
|
| S | S |
|
|
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| B |
| T | T |
|
|  |  |  |  |  |  | S |
| B |
| S | S | T | T | S |
|
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
106 | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | 170 | . | . | . | . |
  |
  |   |
211 | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 280 | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | E | A | M | H | P | L | T | L | M | T | V | G | V | Y | G | K | A | L | P | P | Q | N | G | A | P | V | R | L | I | V | P | W | K | Y | G | F | K | G | I | K | S | I | V | S | I | K | L | T | R | E | R | P | P | T | T | W | N | L | A | A | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
D | E | Y | G | F | Y | A | N | V |
Query Conservation |   |
  |   |
|
|   |   |   |   |
|
|
|   |   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|
|
|
|   |   |
|
|   |
|   |   |   |   |   |
|   |
|
|   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |   |
|   |   |   |   |
|
|
|
|
|   |
|
|
|
|
|
|   |   |   |
|
|   |
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
Template Sequence |   |
D | H | A | T | D | G | E | V | M | L | A | Y | S | M | N | G | A | D | L | P | W | L | N | G | Y | P | L | R | L | V | V | P | G | Y | Y | G | T | Y | W | V | K | H | L | N | E | I | T | V | I | D | K | E | F | D | G | F | W | M | K | T | A | Y | R | I | P | D | N | A | C | A | C | T | E | P | G | K | . |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  | T | S | S |
| S |  |  |  |  |  |  | T | T |  |  |
|
| G | G | G | T | T | T |
|  |  |  |
| T | T | B |
| G | G | G | S |
| B | S |  |  |  |  |  |  |  | S | S |
|
|
|
|  |  |  |  | T | S | S |  |  |  | S | S | T | T | S |
|
|
| T | T |
| . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
175 | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | |
|
|
|
  |
  |   |
282 | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | |
|
|
|
. | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | P | Y | V | D | H | P | R | W | S | Q | A | T | E | R | F | I | G | S | G | G | I | L | D | V | Q | R | Q | P | T | L | L | F | N | G | Y | A | . |
. |
. |
. |
A | Q | V | A | S | L | Y | R | G | L | D | L | R | E | N | F |
Query Conservation |   |
  |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   | . | . | . | . |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |
|   |   |
|   |   |
|   |   |
|   |   |   |
|   |
|   |
|   |
|
|
|   |   |
|   |
|
|
|
|
|   |
|
|
|   |
|
|
Template Sequence |   |
A | P | T | A | T | I | P | I | N | R | F | D | V | R | S | F | I | T | N | V | E | N | G | A | S | V | K | A | G | E | V | P | L | R | G | I | A | F | D | G | G | Y | G | I | T | Q | V | S | V | S | A | D | A | G | K | S | W |
Template Known Secondary structure |   |
|
| S | S |  |  |  |
|
| B |
|
|
|  |  |  |  |
| S |
|
| T | T |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  | S | S | T | T | S | S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
251 | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
  |