|   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
K | V | S | G | Y | N | N | F | Y | E | F | G | L | D | K | A | D | P | A | A | N | A | G | S | L | K | T | D | P | W | T | L | K | I | S | G | E | V | A | K | P | L | T | L | D | H | D | D | L | T | R | R | F | P | L | E | E | R | I | Y | R | M | R | C | V | E | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |
|   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |
|   |
|   |
|
|
|   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|
|   |   |   |   |
|
|
|
|
|   |   |
|
| . | . | . |   |
|   |   |   |
|   |   |   |
|   |
|   |
|   |
|   |
|   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|
Template Sequence |   |
F | L | T | P | V | S | L | H | F | V | R | N | H | G | P | V | P | . |
. |
. |
Y | V | P | D | E | N | I | L | D | W | E | V | S | I | E | G | M | V | E | T | P | Y | K | I | K | L | S | D | I | M | E | Q | F | D | I | Y | S | T | P | V | T | M | V | C | A | G | N | R | R | K | E | Q | N | M | V | K | K | G | A | G |
Template Known Secondary structure |   |
S | S |
|
| G | G | G | S |
|  |  |  | S | S |
|
|
| . | . | . |
|
|
| G | G | G | G | G | G |
|  |  |  |  |  |  | S | B | S | S |
|  |  |  |  |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |
| T | T | T | T |  |  |  |  |  |  |  | S |
|
| S | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | |
|
|
. | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | |
|
. | . | . | 220 | . |
Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
| . | . |
|  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
W | S | M | V | V | P | W | I | G | F | P | L | H | K | L | L | A | L | A | E | P | T | S | N | A | K | Y | V | A | F | E | T | I | Y | A | P | E | Q | M | P | G | Q | Q | D | R | F | I | G | G | G | L | K | Y | P | Y | V | E | G | L | R | L | D | E | A | M | H | P | . |
. |
L | T | L | M | T |
Query Conservation |   |
. | . | . | . | . | . |
|
|   |   |   |   |
|   |
|
|   |
|   |
|
|
|   |   |
|
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |   |
|
|   |   | . | . |   |   |
|
|
|
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|
|
|   |
|
|   |
|
|
|
|   |
|   |
|
|
|   |   |
|
|   |   |   |   |
|   |   |
|   |
|   |
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|
|
|
|   |   |
|
|
|   |   |   |
|
|
|
|
|
Template Sequence |   |
F | N | W | G | A | A | G | T | S | T | S | L | W | T | G | C | M | L | G | D | V | I | G | K | A | R | P | S | K | R | A | R | F | V | W | M | E | G | A | D | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | A | N | G | A | Y | G | T | C | I | R | L | S | W | C | M | D | P | E | R | C | I | M | I | A |
Template Known Secondary structure |   |
|
|
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| B |
| T | T |
|
|  |  |  |  |  |  | S |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T | S | S |
|  |  |  |  |  |  |  |  |  | T |
| T | T | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . |
  |
  |   |
222 | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
V | G | V | Y | G | K | A | L | P | P | Q | N | G | A | P | V | R | L | I | V | P | W | K | Y | G | F | K | G | I | K | S | I | V | S | I | K | L | T | R | E | R | P | P | T | T | W | N | L | A | A | P | D | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | G | F | Y | A |
Query Conservation |   |
  |   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|
|
|
|   |   |
|
|   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|
|
|
|
|
|   |   |
|   |   |
|
|
|
|
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
Y | Q | Q | N | G | E | W | L | H | P | D | H | G | K | P | L | R | V | V | I | P | G | V | I | G | G | R | S | V | K | W | L | K | K | L | V | V | S | D | R | P | S | E | N | W | Y | H | Y | F | D | N | R | V | L | P | T | M | V | T | P | E | M | A | K | S | D | D | R | W | W | K | D | E | R | Y | A | I | Y | D | L |
Template Known Secondary structure |   |
 |  |  | T | T |  |  |
|
| G | G | G | T | T | T |
|  |  |  |
| T | T | B |
| G | G | G | S |
| S | S |  |  |  |  |  |  |  | S | S |
|
|
|
|  |  |  |  | S | S | S | B |
|
|
| T | T |
|
|  |  |  |  |  |  |
| G | G | G | G | S |
| G | G | G | B |
|
| B |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
222 | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . |
  |
  |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | V | N | P | Y | V | D | H | P | R | W | S | Q | A | T | E | R | F | I | G | S | G | G | I | L | D | V | Q | R | Q | P | T | L | L | F | N | G | Y | A | A | Q | V | A | S | L | Y | R | G | L | D | L | R | E | N | F |
Query Conservation |   |
  |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |
|   |   |
|   | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   | . | . |   |   |
|   |
|   |
|   |
|
|
|
|
|   |
|   |
|
|
|
|
|   |
|
|
|   |
|
|
Template Sequence |   |
N | L | Q | T | I | I | C | K | P | E | . |
. |
. |
. |
N | Q | Q | V | I | K | I | S | E | D | E | . |
. |
Y | E | I | A | G | F | G | Y | N | G | G | G | V | R | I | G | R | I | E | V | S | L | D | K | G | K | S | W |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  | S |
| . | . | . | . | T | T |
|  |  |  |
|
| S |
|  | . | . |  |  |  |  |  |  |  |  |
| S | T | T |
|
|  |  |  |  |  |  |  | S | S | T | T | S | S |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
| . | . | . | . |
|
|
|  |  |  |
|
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
302 | . | . | . | . | . | . | . | 310 | . | |
|
|
|
. | . | . | . | . | . | . | . | 320 | . | . | |
|
. | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 |
  |