|   |
55 | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | I | T | L | S | A | L | G | T | F | D | N | F | N | R | Y | A | L | R | G | N | P | G | A | R | T | E | Q | L | Y | D | T | L | F | T | T | S | D | D | E | P | G | S | Y | Y | P | L | I | A | E | S | A | R | Y | A | D | D | Y | S | W | V | E | V | A | I | N | P | R | A | R | F | H | D | G | S | P | I | T | A | R |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|
|
|   |   |
|   |
|   |
|
|   |
|   |
|
|   |
|
|   |
|
|
|
|
|
|
|   |
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |
|
|
|
| . |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|   | . |   |   |   |   |   |   |
|   |
|
|   |
|   |   | . |
|   |
|   |   |
|   |
|
|   |
|
|   |   |
|   |
|
|
|
|   |
|
|
|
|   |
Template Sequence |   |
H | I | H | F | L | F | N | V | S | T | N | S | L | D | P | . |
H | V | D | M | T | Y | I | P | V | R | A | G | I | T | E | T | L | V | R | V | D | E | . |
E | N | V | T | I | A | P | W | L | A | E | S | W | D | . |
S | T | D | G | Q | H | W | T | I | K | L | R | E | D | V | T | F | Q | N | G | K | E | M | D | A | E |
Template Known Secondary structure |   |
 |  |  |  |  |  | S |
|
|
| S |
|
|
| T | . | T | T |
| S | S |
|  |  |  |  | T | T | S |
| B |
| S |  |  |  |
| T | . | T | T |
| S |  |  |  | S | S |  |  |  |  |  | . |
| S | S | S | S |  |  |  |  |  |  |
| S | S |
| B |
| T | T | S |
| B |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
14 | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | |
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
. | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
. | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 |
  |
  |   |
135 | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | V | E | F | T | F | Q | K | F | M | T | E | G | V | P | Q | F | R | L | V | Y | K | G | T | T | V | K | A | I | A | P | L | T | V | R | I | E | L | A | K | P | G | K | E | D | M | L | S | L | F | S | L | P | V | F | P | E | K | Y | W | K | D | H | K | L | S | D | P | L | A | T | P | P | L | A | S | G | P | Y | R |
Query Conservation |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
|   |   | . |
|   |   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
Template Sequence |   |
A | V | K | A | S | L | E | R | A | L | D | E | S | V | . |
A | I | E | N | A | L | K | I | D | E | I | E | A | . |
D | G | Y | T | L | H | I | T | T | K | E | P | F | P | E | F | I | S | E | L | V | N | P | N | V | S | I | I | D | V | T | E | . |
. |
. |
. |
. |
E | D | F | T | N | H | P | V | G | T | G | P | F | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
|  | . |  |  |  |  |  |  |
|  |  |  |  |  |  | . |  | T | T |  |  |  |  |  |  | S | S |
|
| T | T | T | G | G | G | G | G | S | G | G | G |
| B | B |
| T | T | S | . | . | . | . | . |
|
| T | T | T |
|
|
| B | S | S | S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
91 | . | . | . | . | . | . | . | . | 100 | . | . | . | . | |
. | . | . | . | . | 110 | . | . | . | . | . | . | . | |
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
215 | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | T | S | W | K | M | G | Q | N | I | V | Y | S | R | V | K | D | Y | W | A | A | N | L | P | V | N | R | G | R | W | N | F | D | T | I | R | Y | D | Y | Y | L | D | D | N | V | A | F | E | A | F | K | A | G | A | F | D | L | R | M | E | N | D | A | K | N | W | A | T | R | Y | T | G | K | N | F | D | K | K | Y | I |
Query Conservation |   |
|   |   |   |   |   |
|   |   |
|   |
|   |
|
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |
|   | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |
Template Sequence |   |
L | E | S | F | T | P | G | S | K | L | E | L | V | R | Y | D | E | Y | W | . |
. |
. |
. |
. |
. |
. |
D | G | A | S | K | L | D | S | V | T | F | S | F | N | E | D | A | S | A | R | S | L | A | L | E | S | G | Q | A | D | I | V | Y | R | P | E | V | E | S | I | E | T | L | Q | A | N | E | G | I | . |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  | T | T | T |  |  |  |  |  |  |
| T | T |
| T | . | . | . | . | . | . | . | T |
|
|
| S |
| S |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  | S |
|
| T | T | T |  |  |  |  |  |  | S | T | T |  | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | |
|
|
|
|
  |
  |   |
295 | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | K | D | E | Q | K | N | E | S | A | Q | D | T | R | W | L | A | F | N | I | Q | R | P | V | F | S | D | R | R | V | R | E | A | I | T | L | A | F | D | F | E | W | M | N | K | A | L | F | Y | N | A | W | S | R | T | N | S | Y | F | Q | N | T | E | Y | A | A | R | N | Y | P | D | A | A | E | L | V | L | L | A | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |
|
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
M | V | E | A | T | E | T | F | R | T | H | N | L | T | M | N | L | D | R | D | S | L | K | D | V | N | V | R | R | A | V | D | V | L | L | D | R | Q | E | I | V | D | T | I | M | L | G | Y | A | E | V | A | D | G | P | F | I | P | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |
| T | T | S | T | G | G | G | S |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  | T | T | T | T | S |  |  |  |
| S | S | S | S |
| T | T | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
375 | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | |
|
. | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | K | D | L | P | S | E | V | F | T | Q | I | Y | Q | P | P | V | S | K | G | D | G | Y | D | R | D | N | L | L | K | A | D | K | L | L | N | E | A | G | W | V | L | K | G | Q | Q | R | V | N | A | T | T | G | Q | P | L | S | F | E | L | L | L | . |
. |
P | A | S | S | N | S | Q | W | V | L | P | F | Q | H | S |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   | . | . | . |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | F | A | P | S | Y | E | K | K | E | T | G | T | D | I | A | I | Q | Y | L | E | E | A | G | Y | T | L | E | N | Q | . |
. |
. |
M | Q | K | D | G | E | P | L | H | F | T | V | L | T | Y | G | S | R | A | E | L | P | L | I | A | Q | V | F | Q | S | N |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |
|
|
|
|
|
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |
|
|
| . | . | . |  |  |  | T | T |  |  |
|  |  |  |  |  |  |
| S | S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
292 | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | |
|
|
. | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . |
  |
  |   |
453 | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | |
. | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | Q | R | L | G | I | N | M | D | I | R | K | V | D | N | S | Q | I | T | N | R | M | R | S | R | D | Y | D | M | M | P | R | V | W | R | A | . |
M | P | W | P | S | S | D | L | Q | I | S | W | S | S | E | Y | I | N | S | T | Y | N | A | P | G | V | Q | S | P | V | I | D | S | L | I | N | Q | I | I | A | A | Q | G |
Query Conservation |   |
|   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   | . |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |
|   |   |
|
|   |
|
|   |
|
|   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   | . |
Template Sequence |   |
A | K | Q | I | G | I | E | V | E | I | R | Q | I | E | V | P | E | E | Y | M | A | S | N | R | D | W | D | L | I | T | Y | S | N | V | T | S | P | R | G | D | A | G | Y | Y | L | N | A | T | Y | H | P | T | . |
. |
. |
G | A | L | N | F | S | S | V | N | D | P | E | L | T | G | I | I | D | E | L | N | R | T | V | . |
Template Known Secondary structure |   |
 |  |  | T | T |
|  |  |  |  |  |  |
| S | S | S | T |  |  |  |  | T |
| T | T |
|
|  |  |  |  |  |  |  | S |
| T | T | S |
|
|  |  |  |  |  |  |  |  | S | T | T | . | . | . |
| T | T |
|
| S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|
| . |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
354 | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | |
|
|
. | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | |
  |
  |   |
532 | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | K | E | K | L | L | P | L | G | R | A | L | D | R | V | L | T | W | N | Y | Y | M | L | P | M | W | Y | M | A | E | D | R | L | A | W | W | D | K | F | S | Q | P | A | V | R | P | I | Y | S | L | G | I |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
D | Q | D | V | R | A | K | L | T | E | Q | A | A | A | Y | I | D | E | Q | K | I | H | S | F | L | I | H | P | S | A | V | V | A | Y | D | E | N | K | V | K | N | W | V | T | T | R | S | E | Y | Y | M | I |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| B |
|
|
|
|
| S | S | S |
|
|
| S |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . |
  |