|   |
46 | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
. | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
|
|
. | . | . | . | . | 100 | . | . | . | . | . | |
. | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | N | P | A | A | P | K | G | G | Q | I | T | L | S | A | L | G | T | F | D | N | F | N | R | Y | A | L | R | G | N | . |
P | G | A | R | T | E | Q | L | Y | D | T | L | F | T | T | S | D | D | E | . |
. |
. |
P | G | S | Y | Y | P | L | I | A | E | S | . |
A | R | Y | A | D | D | Y | S | W | V | E | V | A | I | N |
Query Conservation |   |
  |
|
|   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |
|
| . | . | . |   |   |   |   |   |
|   |
|
|
|   | . |   |
|   |
|   |
|
|   |
|   |
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |
|   |
|   |   |   |   |
|
|   |
|
|
Template Sequence |   |
V | N | P | S | R | R | R | G | G | T | L | R | L | V | S | S | A | D | V | D | S | L | D | P | A | R | T | Y | Y | V | W | V | W | L | L | Q | R | L | L | N | R | T | L | M | A | Y | P | T | D | P | G | P | A | G | L | V | P | A | P | D | L | A | E | G | P | G | E | V | S | D | G | G | R | T | W | T | Y | R | L | R |
Template Known Secondary structure |   |
B | S |
|
|
|
|
|
| S |  |  |  |  |  |  | S | S |
|
| S |
| S | S | T | T | S |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| S |  |  |
|
| S |
| S | S | G | G | G | G | S |
|  |  | S | S | B | S | S | S |
|  |  |  | G | G | G | T |  |  |  |  |  | B |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . |
  |
  |   |
121 | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 |
Predicted Secondary structure |   |
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | R | A | R | F | H | D | G | S | P | I | T | A | R | D | V | E | F | T | F | Q | K | F | M | T | E | G | V | P | Q | F | R | L | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | K | G | T | T | V | K | A | I | A | P | L | T | V | R | I | E | L | A | K | P | G | K | E | D | M |
Query Conservation |   |
  |
|
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|
|
|   |
|   |   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|
|
|
|   |
|
|
|
|   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
R | G | L | R | Y | D | D | G | T | P | I | T | S | D | D | V | R | H | A | V | Q | R | V | F | A | Q | D | V | L | P | G | G | P | T | Y | L | I | P | L | L | D | D | P | E | R | P | Y | P | G | P | Y | R | T | D | E | P | L | R | S | V | L | T | P | D | E | H | T | I | V | F | R | L | T | R | P | F | S | D | F | D |
Template Known Secondary structure |   |
S | S |
| B |
| T | T | S |
| B |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
| T | T | T | S | T | T | S |
|
| T |  |  |  |  |  |
| B | T | T | B |
|
|
|
| T | T | T |
|
| S |
|
| T | T |  |  |  |  |  | T | T |  |  |  |  |  |
| S | S |
|
| T | T |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
  |
  |   |
181 | . | . | . | |
|
. | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  | . | . |
|
|
|  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | S | L | F | . |
. |
S | L | P | V | F | P | E | K | Y | W | K | D | H | K | L | S | D | P | L | A | T | P | P | L | A | S | G | P | Y | R | V | T | S | W | K | M | G | Q | N | I | V | Y | S | R | V | K | D | Y | W | A | A | N | L | P | V | N | R | G | R | W | N | F | D | T | I | R | Y | D | Y | Y | L | D | D | N |
Query Conservation |   |
  |   |
|   | . | . |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|   |   |   |   |   |
|   |   |
|   |
|   |
|
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |
Template Sequence |   |
H | L | M | A | Q | P | C | A | A | P | V | P | R | R | S | D | T | G | A | D | Y | G | R | D | . |
. |
. |
. |
P | R | S | S | G | P | Y | R | V | A | R | H | E | P | D | T | L | L | H | L | E | R | N | P | H | W | D | R | A | T | D | P | I | R | . |
. |
P | A | L | P | D | R | V | E | L | T | I | G | L | D | V | D |
Template Known Secondary structure |   |
 |  |  | T | S | G | G | G | S |
|
|
| G | G | G |
|
| G | G | G | G | G | G | S | . | . | . | . |
|
|
|
| S | S |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |
| T | T |
|
| G | G | G |
| S | S |
| . | . |
|
|
|
| S |  |  |  |  |  |  |
|
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | |
|
|
|
. | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
|
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
  |
  |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | A | F | E | A | F | K | A | G | A | F | D | L | R | M | E | N | D | A | K | N | W | A | T | R | Y | T | G | K | N | F | D | K | K | Y | I | I | K | D | E | Q | K | N | E | S | A | Q | D | T | R | W | L | A | F | N | I | Q | R | P | V | F | S | D | R | R | V | R | E | A | I | T | L | A | F | D | F | E | W | M | N |
Query Conservation |   |
  |   |   |   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |   |
|
|
|
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |   |
|
|
|
|   |   |
|   |
Template Sequence |   |
V | L | D | A | R | L | I | A | G | E | F | D | I | N | L | E | G | R | G | L | Q | H | A | A | Q | R | R | A | T | A | D | E | V | . |
. |
. |
L | R | S | H | T | D | N | P | R | T | S | F | L | H | F | V | A | M | Q | P | H | I | P | P | F | D | N | V | H | V | R | R | A | V | Q | Y | A | A | D | K | I | L | L | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T | S | S | S |  |  | S | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  | . | . | . |  |  | T | T |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
| T | T | S | T | T | T | T | S |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | |
|
|
. | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
  |
  |   |
339 | 340 | . | . | . | . | . | |
|
. | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
| . | . |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | A | L | F | Y | N | A | . |
. |
W | S | R | T | N | S | Y | F | Q | N | T | E | Y | A | A | R | N | Y | P | D | A | A | E | L | V | L | L | A | P | M | K | K | D | L | P | S | E | V | F | T | Q | I | Y | Q | P | P | V | S | K | G | D | G | Y | D | R | D | N | L | L | K | A | D | K | L | L | N | E | A | G | W | V |
Query Conservation |   |
  |   |   |   |   |
|   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |
Template Sequence |   |
D | A | R | G | G | P | V | N | G | G | D | L | T | T | A | L | F | P | P | T | L | P | A | H | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | L | D | L | Y | P | T | G | P | D | L | R | G | D | L | D | A | A | R | A | E | L | A | A | A | G | L | P |
Template Known Secondary structure |   |
 |  | T | T | T | T | T | S | S |
|  |  |
| S | S | S | S |
| T | T | S | T | T |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| S | S |
|
|
| T | T | S | S |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
| T |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . |
  |
  |   |
417 | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
L | K | G | Q | Q | R | V | N | A | T | T | G | Q | P | L | S | F | E | L | L | L | P | A | S | S | N | S | Q | W | V | L | P | F | Q | H | S | L | Q | R | L | G | I | N | M | D | I | R | K | V | D | N | S | Q | I | T | . |
. |
. |
. |
. |
. |
. |
N | R | M | R | S | R | D | Y | D | M | M | P | R | V | W | R | A | . |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   | . |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
Template Sequence |   |
D | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | R | A | V | I | G | T | Q | R | G | K | F | R | L | V | A | D | A | V | V | E | S | L | A | R | V | G | I | E | L | T | V | K | E | L | D | V | A | T | Y | F | S | L | G | A | G | H | P | E | T | V | R | E | H | G | L | G | L | L | V | T | D | W | G | A | D |
Template Known Secondary structure |   |
T |
| . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |
|
| S | T | T |
|
|
|
|
| T | T |
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
|
| S |
Template Predicted Secondary structure |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
389 | 390 | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . |
  |
  |   |
489 | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | |
|
|
. | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | P | W | P | S | S | D | L | Q | I | S | W | S | S | E | Y | I | . |
. |
. |
N | S | T | Y | N | A | P | G | V | Q | S | P | V | I | D | S | L | I | N | Q | I | I | A | A | Q | G | N | K | E | K | L | L | P | L | G | R | A | L | D | R | V | L | T | W | N | Y | Y | M | L | P | M | W | Y | M | A | E | D | R | L | A |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . |   |
|   |   |
|   |   |
|   |   |
|
|   |
|
|   |
|
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   | . |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|
|
|   |   |   |   |   |   | . |   |   |
Template Sequence |   |
F | P | T | E | Y | G | F | L | A | P | L | V | D | G | R | Q | I | K | R | N | G | G | N | W | N | L | P | E | L | D | D | P | E | V | N | A | L | I | D | E | T | L | H | T | T | . |
D | P | A | A | R | A | E | L | W | R | A | V | E | R | R | V | M | E | H | A | V | L | L | P | L | V | H | D | K | T | L | . |
H | F |
Template Known Secondary structure |   |
S | S | S |  |  |  |  |  |  |  |  |  |
| G | G | G |
|
| T | T | S |
|
|
|
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |
|
| . |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  | . |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
457 | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | |
. | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | |
. | . |
  |
  |   |
566 | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | |
. | . | . | . | . | . | . | 590 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Query Sequence |   |
W | W | D | K | F | S | Q | P | A | V | R | P | I | Y | S | L | G | . |
I | D | T | W | W | Y | D | V |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   | . |   |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |
|   |   |
Template Sequence |   |
R | N | P | W | V | T | N | V | Y | V | H | P | A | F | G | L | Y | D | I | Q | A | M | G | L | A | E |
Template Known Secondary structure |   |
|
| T | T |  |  | S | B |
| B |
| T | T | T | S | S | B |
| G | G | G |
|  |  |
|
|
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
535 | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 |
  |