Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	A	L	D	L	I	R	P	S	V	T	A	M	R	V	I	A	S	V	N	A	D	F	A	R	E	L	K	L	P	P	H	I	R	S	L	G	L	I	S	A	D	S	D	D	V	T	Y	I	A	A	D	E	A	T	K	Q	A	M
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	E	V	V	Y	G	R	S	L	Y	A	G	A	A	H	G	P	S	P	T	A	G	E	V	L	I	M	L	G	G	P	N	P	A	E	V	R	A	G	L	D	A	M	I	A	H	I	E	N	G	A	A	F	Q	W	A	N	D	A	Q
Secondary structure
SS confidence
Disorder							?			?	?	?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	T	A	F	L	A	H	V	V	S	R	T	G	S	Y	L	S	S	T	A	G	I	T	L	G	D	P	M	A	Y	L	V	A	P	P	L	E	A	T	Y	G	I	D	A	A	L	K	S	A	D	V	Q	L	A	T	Y	V	P	P	P
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.
Sequence		S	E	T	N	Y	S	A	A	F	L	T	G	S	Q	A	A	C	K	A	A	C	N	A	F	T	D	A	V	L	E	I	A	R	N	P	I	Q	R	A
Secondary structure
SS confidence
Disorder		?																																	?		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3i82 chain A Region: 2 - 217 Aligned: 216 Modelled: 216 Confidence: 100.0% Identity: 100% PDB header:structural protein Chain: A: PDB Molecule:ethanolamine utilization protein eutl; PDBTitle: ethanolamine utilization microcompartment shell subunit, eutl closed2 form Phyre2 PDB 3io0 chain A Region: 12 - 218 Aligned: 201 Modelled: 207 Confidence: 100.0% Identity: 27% PDB header:structural protein Chain: A: PDB Molecule:etub protein; PDBTitle: crystal structure of etub from clostridium kluyveri Phyre2 PDB 3nwg chain A Region: 35 - 210 Aligned: 157 Modelled: 172 Confidence: 100.0% Identity: 21% PDB header:structural protein Chain: A: PDB Molecule:microcompartments protein; PDBTitle: the crystal structure of a microcomparments protein from2 desulfitobacterium hafniense dcb Phyre2 PDB 3n79 chain A Region: 35 - 210 Aligned: 157 Modelled: 176 Confidence: 100.0% Identity: 13% PDB header:electron transport Chain: A: PDB Molecule:pdut; PDBTitle: pdut c38s mutant from salmonella enterica typhimurium Phyre2 PDB 3ia0 chain C Region: 125 - 213 Aligned: 84 Modelled: 89 Confidence: 99.8% Identity: 25% PDB header:structural protein Chain: C: PDB Molecule:ethanolamine utilization protein euts; PDBTitle: ethanolamine utilization microcompartment shell subunit,2 euts-g39v mutant Phyre2 PDB 3cgi chain D Region: 125 - 213 Aligned: 84 Modelled: 89 Confidence: 99.8% Identity: 26% PDB header:unknown function Chain: D: PDB Molecule:propanediol utilization protein pduu; PDBTitle: crystal structure of the pduu shell protein from the pdu2 microcompartment Phyre2 PDB 2a10 chain A domain 1 Region: 35 - 146 Aligned: 93 Modelled: 104 Confidence: 99.6% Identity: 15% Fold: Ferredoxin-like Superfamily: CcmK-like Family: CcmK-like Phyre2 PDB 2a1b chain A domain 1 Region: 36 - 146 Aligned: 92 Modelled: 103 Confidence: 99.6% Identity: 20% Fold: Ferredoxin-like Superfamily: CcmK-like Family: CcmK-like Phyre2 PDB 3ngk chain A Region: 35 - 140 Aligned: 85 Modelled: 106 Confidence: 99.5% Identity: 22% PDB header:unknown function Chain: A: PDB Molecule:propanediol utilization protein pdua; PDBTitle: pdua from salmonella enterica typhimurium Phyre2 PDB 2ewh chain A domain 1 Region: 34 - 141 Aligned: 88 Modelled: 100 Confidence: 99.5% Identity: 24% Fold: Ferredoxin-like Superfamily: CcmK-like Family: CcmK-like Phyre2 PDB 3i6p chain F Region: 35 - 142 Aligned: 87 Modelled: 108 Confidence: 99.5% Identity: 23% PDB header:structural protein Chain: F: PDB Molecule:ethanolamine utilization protein eutm; PDBTitle: ethanolamine utilization microcompartment shell subunit, eutm Phyre2 PDB 3f56 chain F Region: 30 - 211 Aligned: 166 Modelled: 169 Confidence: 98.9% Identity: 18% PDB header:structural protein Chain: F: PDB Molecule:csos1d; PDBTitle: the structure of a previously undetected carboxysome shell2 protein: csos1d from prochlorococcus marinus med4 Phyre2 PDB 2ctk chain A domain 1 Region: 175 - 218 Aligned: 44 Modelled: 44 Confidence: 37.5% Identity: 20% Fold: Eukaryotic type KH-domain (KH-domain type I) Superfamily: Eukaryotic type KH-domain (KH-domain type I) Family: Eukaryotic type KH-domain (KH-domain type I) Phyre2 PDB 2hh3 chain A Region: 174 - 211 Aligned: 38 Modelled: 38 Confidence: 25.1% Identity: 13% PDB header:rna binding protein Chain: A: PDB Molecule:kh-type splicing regulatory protein; PDBTitle: solution structure of the third kh domain of ksrp Phyre2 PDB 2jnv chain A Region: 169 - 214 Aligned: 41 Modelled: 46 Confidence: 23.6% Identity: 17% PDB header:metal transport Chain: A: PDB Molecule:nifu-like protein 1, chloroplast; PDBTitle: solution structure of c-terminal domain of nifu-like2 protein from oryza sativa Phyre2 PDB 1dtj chain A Region: 169 - 202 Aligned: 34 Modelled: 34 Confidence: 23.0% Identity: 29% Fold: Eukaryotic type KH-domain (KH-domain type I) Superfamily: Eukaryotic type KH-domain (KH-domain type I) Family: Eukaryotic type KH-domain (KH-domain type I) Phyre2 PDB 1khm chain A Region: 174 - 210 Aligned: 37 Modelled: 37 Confidence: 21.9% Identity: 16% Fold: Eukaryotic type KH-domain (KH-domain type I) Superfamily: Eukaryotic type KH-domain (KH-domain type I) Family: Eukaryotic type KH-domain (KH-domain type I) Phyre2 PDB 1xhj chain A Region: 169 - 214 Aligned: 41 Modelled: 41 Confidence: 20.8% Identity: 15% Fold: Alpha-lytic protease prodomain-like Superfamily: Fe-S cluster assembly (FSCA) domain-like Family: NifU C-terminal domain-like Phyre2 PDB 1qd1 chain A domain 1 Region: 152 - 212 Aligned: 60 Modelled: 61 Confidence: 18.9% Identity: 17% Fold: Ferredoxin-like Superfamily: Formiminotransferase domain of formiminotransferase-cyclodeaminase. Family: Formiminotransferase domain of formiminotransferase-cyclodeaminase. Phyre2 PDB 2cte chain A domain 1 Region: 176 - 214 Aligned: 39 Modelled: 39 Confidence: 18.8% Identity: 13% Fold: Eukaryotic type KH-domain (KH-domain type I) Superfamily: Eukaryotic type KH-domain (KH-domain type I) Family: Eukaryotic type KH-domain (KH-domain type I) Phyre2 1 c3i82A_ 2 c3io0A_ 3 c3nwgA_ 4 c3n79A_ 5 c3ia0c_ 6 c3cgiD_ 7 d2a10a1 8 d2a1ba1 9 c3ngkA_ 10 d2ewha1 11 c3i6pF_ 12 c3f56F_ 13 d2ctka1 14 c2hh3A_ 15 c2jnvA_ 16 d1dtja_ 17 d1khma_ 18 d1xhja_ 19 d1qd1a1 20 d2ctea1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3i82A_ 100.0 100 PDB header:structural protein Chain: A: PDB Molecule:ethanolamine utilization protein eutl; PDBTitle: ethanolamine utilization microcompartment shell subunit, eutl closed2 form 2 c3io0A_ 100.0 27 PDB header:structural protein Chain: A: PDB Molecule:etub protein; PDBTitle: crystal structure of etub from clostridium kluyveri 3 c3nwgA_ 100.0 21 PDB header:structural protein Chain: A: PDB Molecule:microcompartments protein; PDBTitle: the crystal structure of a microcomparments protein from2 desulfitobacterium hafniense dcb 4 c3n79A_ 100.0 13 PDB header:electron transport Chain: A: PDB Molecule:pdut; PDBTitle: pdut c38s mutant from salmonella enterica typhimurium 5 c3ia0c_ 99.8 25 PDB header:structural protein Chain: C: PDB Molecule:ethanolamine utilization protein euts; PDBTitle: ethanolamine utilization microcompartment shell subunit,2 euts-g39v mutant 6 c3cgiD_ 99.8 26 PDB header:unknown function Chain: D: PDB Molecule:propanediol utilization protein pduu; PDBTitle: crystal structure of the pduu shell protein from the pdu2 microcompartment 7 d2a10a1 99.6 15 Fold:Ferredoxin-like Superfamily:CcmK-like Family:CcmK-like 8 d2a1ba1 99.6 20 Fold:Ferredoxin-like Superfamily:CcmK-like Family:CcmK-like 9 c3ngkA_ 99.5 22 PDB header:unknown function Chain: A: PDB Molecule:propanediol utilization protein pdua; PDBTitle: pdua from salmonella enterica typhimurium 10 d2ewha1 99.5 24 Fold:Ferredoxin-like Superfamily:CcmK-like Family:CcmK-like 11 c3i6pF_ 99.5 23 PDB header:structural protein Chain: F: PDB Molecule:ethanolamine utilization protein eutm; PDBTitle: ethanolamine utilization microcompartment shell subunit, eutm 12 c3f56F_ 98.9 18 PDB header:structural protein Chain: F: PDB Molecule:csos1d; PDBTitle: the structure of a previously undetected carboxysome shell2 protein: csos1d from prochlorococcus marinus med4 13 d2ctka1 37.5 20 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 14 c2hh3A_ 25.1 13 PDB header:rna binding protein Chain: A: PDB Molecule:kh-type splicing regulatory protein; PDBTitle: solution structure of the third kh domain of ksrp 15 c2jnvA_ 23.6 17 PDB header:metal transport Chain: A: PDB Molecule:nifu-like protein 1, chloroplast; PDBTitle: solution structure of c-terminal domain of nifu-like2 protein from oryza sativa 16 d1dtja_ 23.0 29 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 17 d1khma_ 21.9 16 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 18 d1xhja_ 20.8 15 Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:NifU C-terminal domain-like 19 d1qd1a1 18.9 17 Fold:Ferredoxin-like Superfamily:Formiminotransferase domain of formiminotransferase-cyclodeaminase. Family:Formiminotransferase domain of formiminotransferase-cyclodeaminase. 20 d2ctea1 18.8 13 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 21 d1aisa2 not modelled 15.7 6 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 22 d1j4wa2 not modelled 15.6 21 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 23 c2hh2A_ not modelled 15.5 24 PDB header:rna binding protein Chain: A: PDB Molecule:kh-type splicing regulatory protein; PDBTitle: solution structure of the fourth kh domain of ksrp 24 d1zzka1 not modelled 14.2 16 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 25 c2jzxA_ not modelled 14.0 12 PDB header:rna binding protein Chain: A: PDB Molecule:poly(rc)-binding protein 2; PDBTitle: pcbp2 kh1-kh2 domains 26 d2ctma1 not modelled 13.1 14 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 27 d1j4wa1 not modelled 12.9 21 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 28 c1qd1A_ not modelled 12.8 17 PDB header:transferase Chain: A: PDB Molecule:formiminotransferase-cyclodeaminase; PDBTitle: the crystal structure of the formiminotransferase domain of2 formiminotransferase-cyclodeaminase. 29 c1ztgD_ not modelled 12.3 19 PDB header:dna, rna binding protein/dna Chain: D: PDB Molecule:poly(rc)-binding protein 1; PDBTitle: human alpha polyc binding protein kh1 30 d2axya1 not modelled 11.6 17 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 31 d1ec6a_ not modelled 11.2 26 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 32 c2z51A_ not modelled 11.1 15 PDB header:metal transport Chain: A: PDB Molecule:nifu-like protein 2, chloroplast; PDBTitle: crystal structure of arabidopsis cnfu involved in iron-2 sulfur cluster biosynthesis 33 d1veha_ not modelled 9.6 18 Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:NifU C-terminal domain-like 34 d1nh2a2 not modelled 9.1 10 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 35 d1ftra2 not modelled 8.6 13 Fold:Ferredoxin-like Superfamily:Formylmethanofuran:tetrahydromethanopterin formyltransferase Family:Formylmethanofuran:tetrahydromethanopterin formyltransferase 36 c3krmB_ not modelled 8.4 14 PDB header:rna binding protein Chain: B: PDB Molecule:insulin-like growth factor 2 mrna-binding protein PDBTitle: imp1 kh34 37 d1qnaa2 not modelled 8.3 11 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 38 d1wvna1 not modelled 7.9 21 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 39 c2jvzA_ not modelled 7.7 10 PDB header:splicing Chain: A: PDB Molecule:far upstream element-binding protein 2; PDBTitle: solution nmr structure of the second and third kh domains2 of ksrp 40 d1dt4a_ not modelled 6.9 24 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 41 d1cdwa2 not modelled 6.4 10 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 42 c3dclC_ not modelled 6.3 11 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:tm1086; PDBTitle: crystal structure of tm1086 43 d2ctla1 not modelled 6.3 20 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 44 d1mp9a2 not modelled 6.2 10 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 45 c2wqfA_ not modelled 6.1 24 PDB header:oxidoreductase Chain: A: PDB Molecule:copper induced nitroreductase d; PDBTitle: crystal structure of the nitroreductase cind from2 lactococcus lactis in complex with fmn 46 d1vq3a_ not modelled 5.9 20 Fold:PurS-like Superfamily:PurS-like Family:PurS subunit of FGAM synthetase 47 c2e1mC_ not modelled 5.9 16 PDB header:oxidoreductase Chain: C: PDB Molecule:l-glutamate oxidase; PDBTitle: crystal structure of l-glutamate oxidase from streptomyces sp. x-119-6 48 d1u0ta_ not modelled 5.6 15 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:NAD kinase-like 49 d1nh2a1 not modelled 5.4 10 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 50 d1xpma1 not modelled 5.3 14 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 51 d2h9ec1 not modelled 5.3 18 Fold:Serine protease inhibitors Superfamily:Serine protease inhibitors Family:ATI-like 52 d1iuha_ not modelled 5.2 14 Fold:LigT-like Superfamily:LigT-like Family:2'-5' RNA ligase LigT 53 d1u0ua2 not modelled 5.1 13 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0