|   |
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | |
. | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | R | S | L | L | K | T | K | E | N | L | G | S | G | F | I | S | L | F | R | G | . |
K | K | I | D | D | D | L | F | E | E | L | E | E | Q | L | L | I | A | D | V | G | V | E | T | T | R | K | I | I | T | N | L | T | E | G | A | S | R | K | Q | L | R | D | A | E | A | L | Y | G | L | L | K | E | E | M | G | E |
Query Conservation |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
M | E | K | A | M | L | K | S | A | F | N | F | S | K | D | I | K | K | L | S | K | K | Y | K | Q | A | D | D | E | F | F | E | E | L | E | D | V | L | I | Q | T | D | M | G | M | K | M | V | L | K | V | S | N | L | V | R | K | K | T | K | R | D | T | . |
. |
S | F | E | N | I | K | D | A | L | V | E | S | L | Y | Q |
Template Known Secondary structure |   |
 |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
98 | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | |
|
. | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . |
  |
  |   |
278 | . | 280 | . | . | . | . | |
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | |
|
|
|
. | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  | . | . | . | . |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
Query Sequence |   |
I | L | A | K | V | D | E | . |
P | L | N | V | E | G | K | A | P | F | V | I | L | M | V | G | V | N | G | V | G | K | T | T | T | I | G | K | L | A | R | Q | F | E | Q | Q | G | K | S | V | M | L | A | A | G | D | T | F | R | A | A | A | V | E | Q | L | Q | V | W | G | Q | R | N | N | I | P | . |
. |
. |
. |
V | I |
Query Conservation |   |
  |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |
|   |
|
|   |
|
|   |   |
|   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | Y | T | D | N | D | W | Y | R | I | D | F | K | E | N | R | L | N | I | F | M | L | V | G | V | N | G | T | G | K | T | T | S | L | A | K | M | A | N | Y | Y | A | E | L | G | Y | K | V | L | I | A | A | A | D | T | F | R | A | G | A | T | Q | Q | L | E | E | W | I | K | T | R | L | N | N | K | V | D | L | V | K |
Template Known Secondary structure |   |
 |  |  |
| S |
|
|
|
|
|
|
|
| T | T | S |
|  |  |  |  |  |  | S | S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
| T | T |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
176 | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . |
  |
  |   |
353 | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Q | H | T | G | A | D | S | A | S | V | I | F | D | A | I | Q | A | A | K | A | R | N | I | D | V | L | I | A | D | T | A | G | R | L | Q | N | K | S | H | L | M | E | E | L | K | K | I | V | R | V | M | K | K | L | D | V | E | A | P | H | E | V | M | L | T | I | D | A | S | T | G | Q | N | A | V | S | Q | A | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | N | K | L | N | A | D | P | A | S | V | V | F | D | A | I | K | K | A | K | E | Q | N | Y | D | L | L | L | I | D | T | A | G | R | L | Q | N | K | T | N | L | M | A | E | L | E | K | M | N | K | I | I | Q | Q | V | E | K | S | A | P | H | E | V | L | L | V | I | D | A | T | T | G | Q | N | G | V | I | Q | A | E |
Template Known Secondary structure |   |
| S | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
|
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |
|
| S |  |  |  |  |  |  |  | G | G | G | T |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . |
  |
  |   |
433 | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | F | H | E | A | V | G | L | T | G | I | T | L | T | K | L | D | G | T | A | K | G | G | V | I | F | S | V | A | D | Q | F | G | I | P | I | R | Y | I | G | V | G | E | R | I | E | D | L | R | P | F | K | A | D | D | F | I | E | A | L | F | A | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
|   |
|   |
|
|
|   |
|   |   |   |   |   |
|   |   |
|
|   |
|
Template Sequence |   |
E | F | S | K | V | A | D | V | S | G | I | I | L | T | K | M | D | S | T | S | K | G | G | I | G | L | A | I | K | E | L | L | N | I | P | I | K | M | I | G | V | G | E | K | V | D | D | L | L | A | F | D | I | D | Q | Y | I | V | H | L | S | S | G |
Template Known Secondary structure |   |
 |  | T | T | T | S |
|
|
|  |  |  |  |  |
| G | G | G |
| S |
| T | T |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
| S | S | S | T | T |
|  |  |  |
|
|  |  |  |  |  |  |  |  | T | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . |
  |