|   |
36 | . | . | . | 40 | . | |
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | |
. | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
. | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  | . |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | S | Y | L | I | R | . |
E | E | K | N | V | L | I | D | T | V | D | H | K | F | S | R | E | F | V | Q | N | L | R | N | E | . |
I | D | L | A | D | I | D | Y | I | V | I | N | H | A | E | E | D | H | A | G | A | L | T | E | L | M | A | Q | . |
I | P | D | T | P | I | Y | C | T | A | N | A | I | D | S | I | N | G |
Query Conservation |   |
|
|
|
|
|   | . |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   | . |   |   |   |   |   |
|   |   |
|
|
|
|
|   |
|   |
|
|   |
|   |   |   |   |
|   |   |   | . |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|   |
|
|   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
S | C | I | I | L | E | F | K | G | R | K | I | M | L | D | C | G | I | H | P | G | L | E | G | M | D | A | L | P | Y | I | D | L | I | D | P | A | E | I | D | L | L | L | I | S | H | F | H | L | D | H | C | G | A | L | P | W | F | L | Q | K | T | S | F | K | G | R | T | F | M | T | H | A | T | K | A | I | Y | R | W |
Template Known Secondary structure |   |
|  |  |  |  |  |  | T | T |  |  |  |  |  |
|
|
|
|
| T | T | S |
| G | G | G | G | S |
|
| G | G | G | S |
| G | G | G |
|
|  |  |  |
|
|
| S | S |  |  |  |  | T | T |  |  |  |  |  |  |  | S | S |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
26 | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . |
  |
  |   |
113 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | |
|
. | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | H | H | H | P | E | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | F | N | V | V | K | T | G | D | T | L | D | I | G | N | G | K | Q | L | I | F | V | E | T | P | M | L | H | W | P | D | S | M | M | T | Y | L | . |
. |
T | G | D | A | V | L | F | S | N | D | A | F | G | Q | H | Y | C | D | E | H | L | F |
Query Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |
|   |   |
|   |
|
|   |
|   |   |
|   |   |
|   |
|
|   |   |
|
|
|   |   |   |   |   |
|   | . | . |   |   |   |   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|   | . | . | . | . | . | . | . | . | . |   |   |
Template Sequence |   |
L | L | S | D | Y | V | K | L | Y | T | E | T | D | L | E | E | S | M | D | K | I | E | T | I | N | F | H | E | V | K | E | V | A | G | . |
. |
. |
I | K | F | W | C | Y | H | A | G | H | V | L | G | A | A | M | F | M | I | E | I | A | G | V | K | L | L | Y | T | G | D | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
S | R |
Template Known Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | G | G | G |  |  |  |  |
| T | T |
|
|  |  |  | T | T | . | . | . |  |  |  |  |  |  |  |
|
| S | S | T | T |
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |
|
| S |
| . | . | . | . | . | . | . | . | . |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
| . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
106 | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | |
|
|
|
|
|
|
|
|
. | . |
  |
  |   |
179 | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
. | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
N | D | E | V | D | Q | T | E | L | F | E | Q | C | Q | R | Y | Y | A | N | I | L | T | P | F | S | R | L | V | T | P | K | I | T | E | I | L | G | F | N | L | P | V | D | M | I | A | T | S | H | G | V | V | W | R | D | N | P | T | Q | I | V | E | L | Y | L | K | W | A | A | D | Y | Q | E | D | . |
R | I | T | I | F |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|   |   |
|   |
|   |
|   |   |
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   | . |
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
Template Sequence |   |
Q | M | A | A | E | I | P | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | K | P | D | I | L | I | I | E | S | T | Y | G | T | H | I | H | E | K | R | E | E | R | E | A | R | F | C | N | T | V | H | D | I | V | N | R | G | G | R | G | L | I |
Template Known Secondary structure |   |
|
|
|
|
|
|
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |
|
| S |  |  |  |  |  |
| T | T | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
183 | . | . | . | . | . | . | 190 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . |
  |
  |   |
258 | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | D | T | M | S | N | N | T | R | M | M | A | D | A | I | A | Q | G | I | A | E | T | D | P | R | V | A | V | K | I | F | N | V | A | R | S | D | K | N | E | I | L | T | N | V | F | R | S | K | G | V | L | V | G | T | S | T | M | N | N | V | M | M | P | K | I | A | G | L | V | E | E | M | T | G | L | R | F | R | N |
Query Conservation |   |
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|
|   |
|
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |
Template Sequence |   |
P | V | F | A | L | G | R | A | Q | E | L | L | L | I | L | D | E | Y | W | Q | N | H | P | E | L | H | D | I | P | I | Y | Y | A | F | K | H | I | S | N | L | K | S | M | D | H | F | D | D | I | G | P | S | V | V | M | A | S | P | G | M | M | Q | S | G | L | S | R | E | L | F | E | S | W | . |
. |
. |
C | T | D | K |
Template Known Secondary structure |   |
 |
|
| S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | T | T | S |
|  |  |  |
|
|
| S |  |  |  |
|
|
| T | T | S | S |
|
|
| S | S |  |  |  |  |  | S |
| T | T |
| S | S |  |  |  |  |  |  |  |  |  |  | . | . | . | T | T |
| T |
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | |
|
|
. | . | . | . |
  |
  |   |
338 | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | R | A | S | A | F | G | S | H | G | W | S | G | G | A | V | D | R | L |
Query Conservation |   |
|   |   |   |   |
|
|
|
|
|
|   |
|   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | N | G | V | I | I | A | G | Y | C | V | E | G | T | L | A | K | H | I |
Template Known Secondary structure |   |
T |
|  |  |  |  |
| S |
|
|
| T | T | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
349 | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . |
  |