|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
. | . | . | . | . | . | 40 | . | . | |
. | . | . | . | . | . | . | 50 | . | |
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | I | V | V | K | N | N | I | H | W | V | G | Q | R | D | W | E | V | R | D | F | H | G | T | E | Y | K | T | L | R | G | S | . |
S | Y | N | S | Y | L | I | R | E | . |
E | K | N | V | L | I | D | T | V | . |
D | H | K | F | S | R | E | F | V | Q | N | L | R | N | E | I | D | L | A | D | I | D | Y | I | V | I | N |
Query Conservation |   |
  |
|   |
|   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
| . |
|   |
|
|
|
|
|   |   | . |   |   |   |   |
|
|
|
|   | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |
|   |   |
|
|   |
|
Template Sequence |   |
I | T | Q | L | S | D | K | V | Y | T | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | S | L | A | E | I | E | G | M | V | P | S | N | G | M | I | V | I | N | N | H | Q | A | A | L | L | D | T | P | I | N | D | A | Q | T | E | T | L | V | N | W | V | A | D | S | L | H | . |
A | K | V | T | T | F | I | P | N |
Template Known Secondary structure |   |
 |  |  | S | S | S | S |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  | S |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|  |  |  |  |  |  |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
30 | . | . | . | . | . | . | . | . | . | 40 | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | |
. | . | 90 | . | . | . | . | . | . |
  |
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | A | E | E | D | H | A | G | A | L | T | E | L | M | A | Q | I | P | D | T | P | I | Y | C | T | A | N | A | I | D | S | I | N | G | H | H | H | H | P | E | W | N | F | N | V | V | K | T | G | D | T | L | D | I | G | N | G | K | Q | L | I | F | V | E | T | P | M | L | H | W | P | D | S | M | M | T | Y | L | T | G |
Query Conservation |   |
|   |
|   |
|
|   |
|   |   |   |   |
|   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|
|   |
|   |   |
|   |   |
|   |
|
|   |   |
|
|
|   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|
|   |
|
|   |   |   |
|   |   |   | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
H | W | H | G | D | C | I | G | G | L | G | Y | L | Q | K | K | . |
. |
G | V | Q | S | Y | A | N | Q | M | T | I | D | L | A | K | E | K | G | L | . |
. |
P | V | P | E | H | G | F | T | D | S | L | T | V | S | L | D | . |
G | M | P | L | Q | C | Y | Y | L | G | G | G | H | A | T | D | N | I | V | V | W | L | P | T |
Template Known Secondary structure |   |
S | S | S |  |  |  |  | T | T |  |  |  |  |  |  | T | . | . | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . |
|
|
| S |  |  |  | S | S |  |  |  |  |  |  | T | . | T |  |  |  |  |  |  |
|
|
|
| S | S | S | T | T |
|
|  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
| . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
99 | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
. | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . |
  |
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | A | V | L | F | S | N | D | A | F | G | Q | H | Y | C | D | E | H | L | F | N | D | E | V | D | Q | T | E | L | F | E | Q | C | Q | R | Y | Y | A | N | I | L | T | P | F | S | R | L | V | T | P | K | I | T | E | I | L | G | F | N | L | P | V | D | M | I | A | T | S | H | G | V | V | W | R | D | N | P | T | Q | I |
Query Conservation |   |
  |   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|   |   |
|   |
|   |
|   |   |
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
E | N | I | L | F | G | G | C | M | L | K | D | N | Q | A | T | S | I | G | N | I | S | D | A | D | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | A | W | P | K | T | L | D | K | V | K | A | K | F | P | S | A | R | Y | V | V | P | G | H | G | D | Y | G | G | T | E | L | I | E | H |
Template Known Secondary structure |   |
T | T |  |  |  |  |  | T | T | S |
|
| T | T |
|
| S |
|
|
|
| T | T |
|
| T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
| S |  |  |  |  | S | S | S |
|
| B | S | T |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
  |
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | E | L | Y | L | K | W | A | A | D | Y | Q | E | D |
Query Conservation |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | K | Q | I | V | N | Q | Y | I | E | S | T | S | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
  |