|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | |
|
. | . | . | . | 40 | . | . | |
. | . | . | . | . | . | . | 50 | . | . | |
. | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  | . | . |  |  |  |  |  |  |
| . |
|
|  |  |  |  |
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | I | V | V | K | N | N | I | H | W | V | G | Q | R | D | W | E | V | R | D | F | H | G | T | E | Y | K | T | L | R | G | S | S | Y | . |
. |
N | S | Y | L | I | R | E | . |
E | K | N | V | L | I | D | T | V | D | . |
H | K | F | S | R | E | F | V | Q | N | L | R | N | E | I | D | L | A | D | I | D | Y | I | V | I |
Query Conservation |   |
  |
|   |
|   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   | . | . |
|
|
|
|
|   |   | . |   |   |   |   |
|
|
|
|   |   | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |
|   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |
|   |   |
|
|   |
Template Sequence |   |
I | E | K | L | K | D | N | L | Y | V | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | T | Y | N | T | F | N | G | T | K | Y | A | A | N | A | V | Y | L | V | T | D | K | G | V | V | V | I | D | C | P | W | G | E | D | K | F | K | S | F | T | D | E | I | Y | K | K | H | G | . |
K | K | V | I | M | N | I | A |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  | S |
|
| S | S | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
44 | . | . | . | . | . | 50 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | |
. | . | . | . | . | . | . | 110 |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | H | A | E | E | D | H | A | G | A | L | T | E | L | M | A | Q | I | P | D | T | P | I | Y | C | T | A | N | A | I | D | S | I | N | G | H | H | H | H | P | E | W | N | F | N | V | V | K | T | G | D | T | L | D | I | G | N | G | K | Q | L | I | F | V | E | T | P | M | L | H | W | P | D | S | M | M | T | Y | L | T |
Query Conservation |   |
|
|   |
|   |
|
|   |
|   |   |   |   |
|   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|
|   |
|   |   |
|   |   |
|   |
|
|   |   |
|
|
|   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |
|
|   |
|
|   |   |   |
|   |   |   | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
T | H | S | H | D | D | R | A | G | G | L | E | Y | F | G | K | I | . |
. |
G | A | K | T | Y | S | T | K | M | T | D | S | I | L | A | K | E | N | K | . |
. |
P | R | A | Q | Y | T | F | D | N | N | K | S | F | K | V | G | . |
K | S | E | F | Q | V | Y | Y | P | G | K | G | H | T | A | D | N | V | V | V | W | F | P |
Template Known Secondary structure |   |
S | S | S | S | T | T | T | T | T | T |  |  |  |  |  |  | T | . | . | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . |
|
|
| S |  |  |  | S | S |
|  |  |  |  |  | T | . | T |  |  |  |  |  |  |
|
|
| S | S | S | S | S | S |
|
|  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |
| . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
115 | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | |
|
. | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | |
|
. | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . |
  |
  |   |
158 | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | |
. | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  | . |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
G | D | A | V | L | F | S | N | D | A | F | G | Q | H | Y | C | D | E | H | L | F | N | D | E | V | D | Q | T | E | L | F | E | Q | C | Q | R | Y | Y | A | N | I | L | T | P | F | S | R | L | V | T | P | K | I | T | E | I | L | G | F | N | L | P | V | D | M | I | A | T | S | H | G | V | V | W | . |
R | D | N | P | T |
Query Conservation |   |
  |   |   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|   |   |
|   |
|   |
|   |   |
|   |
|
|
|
|
|
|   | . |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |
Template Sequence |   |
K | E | K | V | L | V | G | G | C | I | I | K | S | A | D | S | K | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | G | Y | I | G | E | A | Y | V | N | D | W | T | Q | S | V | H | N | I | Q | Q | K | F | S | G | A | Q | Y | V | V | A | G | H | D | D | W | K | D | Q | R | S | I | Q |
Template Known Secondary structure |   |
T | T | T |  |  |  |  |  | T | T | S |
|
| T | T |
| S | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S |  |  |  |  | S | B | S |
|
|
| S | T | T |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 |
  |
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | I | V | E | L | Y | L | K | W | A | A | D | Y |
Query Conservation |   |
  |
|
|   |   |
|   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
H | T | L | D | L | I | N | E | Y | Q | Q | K | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
285 | . | . | . | . | 290 | . | . | . | . | . | . | . |
  |