Return to main results Retrieve Phyre Job Id

Job DescriptionP0A884
Confidence100.00%DateThu Jan 5 11:07:10 GMT 2012
Rank4Aligned Residues261
% Identity48%Templatec3jsuA_
PDB info PDB header:oxidoreductase, transferaseChain: A: PDB Molecule:dihydrofolate reductase-thymidylate synthase; PDBTitle: quadruple mutant(n51i+c59r+s108n+i164l) plasmodium falciparum2 dihydrofolate reductase-thymidylate synthase(pfdhfr-ts) complexed3 with qn254, nadph, and dump
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.........70.........80.
Predicted Secondary structure 






























Query SS confidence 















































































Query Sequence  KQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWD
Query Conservation 



 

  

  
    



  
  


   
 

   







   
  
 



 
 
      
 
    

 
Alig confidence 















































































Template Conservation   


 
   

  
    



  
 
 

   
 

   







   
    




  
 

   
 
 

 


Template Sequence  YQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKFDLSQYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWE
Template Known Secondary structure 


SSSS
TTT




SSS



TT

BTTT

TTG
Template Predicted Secondary structure 































Template SS confidence 















































































   326...330.........340.........350.........360.........370.........380.........390.........400.....
 
   82.. .....90.........100... ......110.........120.........130.........140.
Predicted Secondary structure 

............













........


















Query SS confidence 


. . . . . . . . . . . .


















. . . . . . . .





































Query Sequence  EWA. . . . . . . . . . . . DENGDLGPVYGKQWRAWPT. . . . . . . . PDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKM
Query Conservation     ............   
 

  

 
 
    ........      


  

  

  
 


 

  


 
    
Alig confidence 


............


















........





































Template Conservation   
                



 


 


 
          
    



  

  

 

 


 
   


 

  
Template Sequence  ANGTREFLDNRKLFHREVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVKDLDQM
Template Known Secondary structure  GGSSTT
TTS
TTB

S
BTS



TTS

TT
SB

TT
S




TTTGGGS
Template Predicted Secondary structure 



















































Template SS confidence 















































































   406...410.........420.........430.........440.........450.........460.........470.........480.....
 
   142.......150.........160.........170.........180.........190.........200.........210.........220.
Predicted Secondary structure 











Query SS confidence 















































































Query Sequence  ALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLS
Query Conservation   
 

    

 
  
 
     


 
  

 
 

     
   

   

  
   
     


  
 
 
 
 
 
Alig confidence 















































































Template Conservation 





   

 
  
 
     


 
  

 



  



   

   

  
   
 


 


 



   


 
Template Sequence  ALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHVLGNAHVYNNHIDSLKIQLN
Template Known Secondary structure  SS

STTTTTTT
GGGTT
Template Predicted Secondary structure 




















Template SS confidence 















































































   486...490.........500.........510.........520.........530.........540.........550.........560.....
 
   222.......230.........240.........250.........260..
Predicted Secondary structure 
























Query SS confidence 








































Query Sequence  REPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPV
Query Conservation 
 
   
 
               
  
  
     
    
Alig confidence 








































Template Conservation 
 
   
 
 
      
 

   

 
  
  
  
   
Template Sequence  RIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHEKISMDM
Template Known Secondary structure  S






TT

STTS

GGG








S

Template Predicted Secondary structure 


























Template SS confidence 








































   566...570.........580.........590.........600......
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions