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Job DescriptionP0A884
Confidence100.00%DateThu Jan 5 11:07:10 GMT 2012
Rank1Aligned Residues263
% Identity51%Templatec2oipE_
PDB info PDB header:transferase, oxidoreductaseChain: E: PDB Molecule:chain a, crystal structure of dhfr; PDBTitle: crystal structure of the s290g active site mutant of ts-2 dhfr from cryptosporidium hominis
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.........70.........80.
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Query Sequence  KQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWD
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Template Sequence  FQYLDLLSRVLENGAYRENRTGISTYSIFGQMMRFDMRESFPLLTTKKVAIRGIFEELIWFIKGDTNGNHLIEKKVYIWS
Template Known Secondary structure  S


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   238.240.........250.........260.........270.........280.........290.........300.........310.......
 
   82... ....90.........100... ......110.........120.........130.........140.
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Query Sequence  EWAD. . . . . . . . . . . . ENGDLGPVYGKQWRAWPT. . . . . . . . PDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKM
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Template Sequence  GNGSKEYLERIGLGHREENDLGPIYGFQWRHYNGEYKTMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQM
Template Known Secondary structure  TTTSTTTTTS
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   318.320.........330.........340.........350.........360.........370.........380.........390.......
 
   142.......150..... ....160.........170.........180.........190.........200.........210.........220
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Query Sequence  ALAPCHAFFQFYVA. DGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQL
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Template Sequence  ALPPCHVLSQYYVTNDNCLSCNLYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQL
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S
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   398.400.........410.........420.........430.........440.........450.........460.........470.......
 
   221........230.........240.........250.........260....
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Query Sequence  SREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI
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Template Sequence  SRTPRPFPQLKFKRKVENIEDFKWEDIELIGYYPYPTIKMDMAV
Template Known Secondary structure  S





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   478.480.........490.........500.........510.........520.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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