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Job DescriptionP0A884
Confidence100.00%DateThu Jan 5 11:07:10 GMT 2012
Rank12Aligned Residues262
% Identity49%Templatec2aazG_
PDB info PDB header:transferaseChain: G: PDB Molecule:thymidylate synthase; PDBTitle: cryptococcus neoformans thymidylate synthase complexed with2 substrate and an antifolate
Resolution2.08 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30. ........40. ........50.........60.........70.........
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Query Sequence  KQYLELMQKVLDEGTQKNDRTGTGTLSIFG. HQMRFNLQDG. FPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTI
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Template Sequence  YQYLDLIRRIINVGEVRPDRTGTGTVALFAPPSFRFSLADNTLPLLTTKRVFLRGVIAELLWFVSGCTDAKMLSSQGVGI
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   21........30.........40.........50.........60.........70.........80.........90.........100
 
   80..... ....90.........100... ......110.........120.........130.........
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Query Sequence  WDEWAD. . . . . . . . . . . . ENGDLGPVYGKQWRAWPT. . . . . . . . PDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELD
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Template Sequence  WDGNGSKEFLEKVGLGHRREGDLGPVYGFQWRHFGAEYTDADGDYKGKGVDQLQRVIDTIKNNPTDRRIILSAWNPKDLP
Template Known Secondary structure  TSTT
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   101........110.........120.........130.........140.........150.........160.........170.........180
 
   140.........150..... ....160.........170.........180.........190.........200.........210
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Query Sequence  KMALAPCHAFFQFYVA. . . . . . . . . DGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYS
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Template Sequence  LMALPPCHMFCQFFVSLPPADSPGSKPKLSCLMYQRSCDLGLGVPFNIASYALLTHMIALITDTEPHEFILQMGDAHVYR
Template Known Secondary structure  GSSS

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   181........190.........200.........210.........220.........230.........240.........250.........260
 
   211........220.........230... ......240.........250.........260...
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Query Sequence  NHMDQTHLQLSREPRPLPKLIIK. . . RKPESIFDYRFEDFEIEGYDPHPGIKAPVA
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Template Sequence  DHVEPLKTQLEREPRDFPKLKWARSKEEIGDIDGFKVEDFVVEGYKPWGKIDMKMS
Template Known Secondary structure  GGTS





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   261........270.........280.........290.........300.........310......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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