Job Description P0A884 Confidence 100.00% Date Thu Jan 5 11:07:10 GMT 2012 Rank 18 Aligned Residues 247 % Identity 56% Template c1hw4A_ PDB info PDB header:transferase Chain: A: PDB Molecule:thymidylate synthase; PDBTitle: structure of thymidylate synthase suggests advantages of chemotherapy2 with noncompetitive inhibitors Resolution 2.06 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	Q	Y	L	E	L	M	Q	K	V	L	D	E	G	T	Q	K	N	D	R	T	G	T	G	T	L	S	I	F	G	H	Q	M	R	F	N	L	Q	D	G	F	P	L	V	T	T	K	R	C	H	L	R	S	I	I	H	E	L	L	W	F	L	Q	G	D	T	N	I	A	Y	L	H	E	N	N	V	T	I	W	D
Query Conservation
Alig confidence													.																																																																	.	.	.	.
Template Conservation													.																																																																	.	.	.	.
Template Sequence		L	Q	Y	L	G	Q	I	Q	H	I	L	.	R	G	V	R	K	D	D	R	T	G	T	G	T	L	S	V	F	G	M	Q	A	R	Y	S	L	R	D	E	F	P	L	L	T	T	K	R	V	F	W	K	G	V	L	E	E	L	L	W	F	I	K	G	S	T	N	A	K	E	L	S	S	K	G	V	.	.	.	.
Template Known Secondary structure													.								T	T	S																S	S						S	S	S																T	T			B						T	T	T		.	.	.	.
Template Predicted Secondary structure													.																																																																	.	.	.	.
Template SS confidence
		31	.	.	.	.	.	.	.	.	40	.		.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.									.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.
Predicted Secondary structure																								.	.	.	.	.	.	.	.
Query SS confidence																								.	.	.	.	.	.	.	.
Query Sequence		E	W	A	D	E	N	G	D	L	G	P	V	Y	G	K	Q	W	R	A	W	P	T	.	.	.	.	.	.	.	.	P	D	G	R	H	I	D	Q	I	T	T	V	L	N	Q	L	K	N	D	P	D	S	R	R	I	I	V	S	A	W	N	V	G	E	L	D	K	M	A	L	A	P	C	H	A	F	F	Q	F	Y
Query Conservation																								.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.																	.	.	.	.	.	.	.	.																												.																			.
Template Conservation		.	.	.	.	.	.																																																				.																			.
Template Sequence		.	.	.	.	.	.	G	D	L	G	P	V	Y	G	F	Q	W	R	H	F	G	A	E	Y	R	D	M	E	S	D	Y	S	G	Q	G	V	D	Q	L	Q	R	V	I	D	T	I	K	T	N	P	D	D	R	R	I	I	M	.	A	W	N	P	R	D	L	P	L	M	A	L	P	P	C	H	A	L	.	Q	F	Y
Template Known Secondary structure		.	.	.	.	.	.		B			S									B	T	S					T	T	S			T	T		S	B														T	T		S					.				G	G	G	T	T	T	S	S	S				S	B		.
Template Predicted Secondary structure		.	.	.	.	.	.																																																				.																			.
Template SS confidence
								129	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.		180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.		.	.	200
		154	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	A	D	G	K	L	S	C	Q	L	Y	Q	R	S	C	D	V	F	L	G	L	P	F	N	I	A	S	Y	A	L	L	V	H	M	M	A	Q	Q	C	D	L	E	V	G	D	F	V	W	T	G	G	D	T	H	L	Y	S	N	H	M	D	Q	T	H	L	Q	L	S	R	E	P	R	P	L	P	K	L	I	I	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	V	N	S	E	L	S	C	Q	L	Y	Q	R	S	G	D	M	G	L	G	V	P	F	N	I	A	S	Y	A	L	L	T	Y	M	I	A	H	I	T	G	L	K	P	G	D	F	I	H	T	L	G	D	A	H	I	Y	L	N	H	I	E	P	L	K	I	Q	L	Q	R	E	P	R	P	F	P	K	L	R	I	L
Template Known Secondary structure				T	T													T	T	T																				T	T																	G	G	G								T	T	S
Template Predicted Secondary structure
Template SS confidence
		203	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	K	P	E	S	I	F	D	Y	R	F	E	D	F	E	I	E	G	Y	D	P	H	P	G	I	K	A	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	K	V	E	K	I	D	D	F	K	A	E	D	F	Q	I	E	G	Y	N	P	H	P	T	I	K	M	E
Template Known Secondary structure		S				S	G	G	G			G	G	G					S
Template Predicted Secondary structure
Template SS confidence
		283	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions