|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
T | L | V | V | A | L | G | G | N | A | L | L | Q | R | G | E | A | L | T | A | E | N | Q | Y | R | N | I | A | S | A | V | P | A | L | A | R | L | A | R | . |
S | Y | R | L | A | I | V | H | G | N | G | P | Q | V | G | L | L | A | L | Q | N | L | A | W | K | E | V | E | P | Y | P | L | . |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   | . |
|   |   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |
|
|
|
|
|
|
|
|
|   |
|   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
T | T | V | M | K | F | G | G | T | S | V | G | S | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | R | I | R | H | V | A | K | I | V | T | K | R | K | K | E | D | D | D | V | V | V | V | V | S | A | M | S | E | V | T | N | A | L | V | E | I | S | Q | Q | A | L | D | V | R | D | I | A | K | V | G | D | F | I | K | F |
Template Known Secondary structure |   |
|  |  |  |  |  |
| T | G | G | G | S | S |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
74 | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | V | L | V | A | E | S | Q | G | M | I | G | Y | M | L | A | Q | S | L | S | A | Q | P | Q | M | P | P | V | T | T | V | L | T | R | I | E | V | S | P | D | D | P | A | F | L | Q | P | E | K | F | I | G | P | V | Y | Q | P | E | E | Q | E | A | L | E | A | A | Y | G | W |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |
|   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|
Template Sequence |   |
I | R | E | K | H | Y | K | A | I | E | E | A | I | K | S | E | E | I | K | E | E | V | K | K | I | I | D | S | R | I | E | E | L | E | K | V | L | I | G | V | A | Y | L | G | E | L | T | P | K | S | R | D | Y | I | L | S | F | G | E | R | L | S | S | P | I | L | S | G | A | I | R | D | L | G | E | K | S | I | A | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
72 | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . |
  |
  |   |
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | M | K | R | D | G | K | Y | L | R | R | V | V | A | S | P | Q | P | R | K | I | L | D | S | E | A | I | E | L | L | L | K | E | G | H | V | V | I | C | S | G | G | G | G | V | P | V | T | D | D | G | A | G | S | E | A | V | I | D | K | D | L | A | A | A | L | L | A | E | Q | I | N | A | D | G | L | V | I | L | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|   |   |
|   |
|   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|   |
|
|
|
|   | . |   |   |   |
|   |   |   |   |
|
|
|
|   |
|
|   |   |
|
|   |
|
|   |   |
|   |
|   |   |
|   |
|   |
|
Template Sequence |   |
E | G | G | E | A | G | I | I | T | D | N | N | F | G | S | A | R | V | K | R | L | E | V | K | E | R | L | L | P | L | L | K | E | G | I | I | P | V | V | T | G | F | I | G | T | . |
T | E | E | G | Y | I | T | T | L | G | R | G | G | S | D | Y | S | A | A | L | I | G | Y | G | L | D | A | D | I | I | E | I | W | T |
Template Known Secondary structure |   |
| T | T | T | T | T |  |  |  |
| S |
| T | T | S |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  | S | S |  |  |  | . |
| T | T |
|
|  |  |  |
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
| . |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | |
. | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 |
  |
  |   |
223 | . | . | . | . | . | . | 230 | . | . | . | |
|
. | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
. | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | A | D | A | V | Y | E | N | W | G | T | . |
. |
P | Q | Q | R | A | I | R | H | A | T | P | D | E | L | A | P | F | A | K | A | D | . |
G | S | M | G | P | N | V | T | A | V | S | G | Y | V | R | S | R | G | K | P | A | W | I | G | A | L | S | R | I | E | E | T | L | A | G | E | A | G | T | C | I | S |
Query Conservation |   |
|
|   |
|
|
|   |   |   |
|   | . | . |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   | . |
|
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |
|   |   |
|
|   |
|   |   |
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|
|   |
|
|   |   |   |
|   |   |
|
|
|
|   | . | . | . |
|
|   |   |
|   |   |   |   |
|
|
|   |
|   |
|   |   |   | . | . | . | . | . |   |   |   |   |
|
|   |
|   |
Template Sequence |   |
D | V | S | G | V | Y | T | T | D | P | R | L | V | P | T | A | R | R | I | P | K | L | S | Y | I | E | A | M | E | L | A | Y | F | G | A | K | V | L | H | P | R | . |
. |
. |
T | I | E | P | A | M | E | K | G | I | P | I | L | V | K | N | T | F | E | . |
. |
. |
. |
. |
P | E | S | E | G | T | L | I | T |
Template Known Secondary structure |   |
S | S | S | S |
| B | S | S |
| T | T | T |
| T | T |
|
| B |
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T | S |
| G | G | . | . | . | G |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  | T | T | S | . | . | . | . | . | T | T | S |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . |
|
|
|
|
|
|  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
231 | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
|
|
. | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
|
|
|
. | . | . | . | . | . | . | . | . |
  |