|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | V | A | L | G | G | N | A | L | L | Q | R | G | E | A | L | T | A | E | N | Q | Y | R | N | I | A | S | A | V | P | A | L | A | R | L | A | R | . |
S | Y | R | L | A | I | V | H | G | N | G | P | Q | V | G | L | L | A | L | Q | N | L | A | W | K | E | V | E | P | Y | P | L | D | V | L | V | A | E | S | Q | G |
Query Conservation |   |
|
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   | . |
|   |   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|
|
|
|
|   |
|   |
| . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
Template Sequence |   |
I | V | Q | K | F | G | G | T | S | V | G | T | V | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | I | Q | A | V | A | Q | R | I | K | R | T | V | Q | G | G | N | S | L | V | V | V | V | S | A | M | G | K | S | T | D | V | L | V | D | L | A | Q | Q | I | S | P | N | P | C | R | R | E | M | D | M | L | L | S | T | G |
Template Known Secondary structure |   |
 |  |  |  |  |
| S | G | G | G | S | S |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |
|
|
| S | T |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . |
  |
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | I | G | Y | M | L | A | Q | S | L | S | A | Q | P | Q | M | P | P | V | T | T | V | L | T | R | I | E | V | S | P | D | D | P | A | F | L | Q | P | E | K | F | I | G | P | V | Y | Q | P | E | E | Q | E | A | L | E | A | A | Y | G | W | Q | M | K | R | D | G | K | Y | L | R | R | V | V | A | S | P | Q | P | R | K |
Query Conservation |   |
  |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
|   |   |
|
| . | . | . | . | . | . |   |
|
|   |   |   |
|   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
Template Sequence |   |
E | Q | V | S | I | . |
. |
. |
. |
. |
. |
A | L | L | S | L | A | L | Q | E | I | D | Q | P | A | I | S | L | T | G | A | Q | V | G | I | V | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | L |
Template Known Secondary structure |   |
 |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  | G | G | G | T |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
74 | . | . | . | . | |
|
|
|
|
|
. | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . |
  |
  |   |
163 | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | |
|
. | . | . | . | . | . | 240 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
Query Sequence |   |
I | L | D | S | E | A | I | E | L | L | L | K | E | G | H | V | V | I | C | S | G | G | G | G | V | P | V | T | D | D | G | A | G | S | E | A | V | I | D | K | D | L | A | A | A | L | L | A | E | Q | I | N | A | D | G | L | V | I | L | T | D | A | D | A | V | Y | E | N | W | G | T | . |
. |
P | Q | Q | R | A | I | R |
Query Conservation |   |
  |
|   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|   |   |
|   |
|   |   |
|
|   |   |
|
|
|   |
|
|
|   |   |   |
|   | . | . |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|   |
|
|   |
| . |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |
|   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |
|   |
Template Sequence |   |
E | I | R | P | D | R | L | E | H | H | L | R | E | G | K | V | V | V | V | A | G | F | Q | G | . |
I | S | E | H | L | E | I | T | T | L | G | R | G | G | S | D | T | S | A | V | A | L | A | A | A | L | K | A | D | F | C | E | I | Y | T | D | V | P | G | I | L | T | T | D | P | R | L | V | P | E | A | Q | L | M | A |
Template Known Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  | T | T | T |
|  |  |  |  |  |
|  |  |  | . |  |
|
|  |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  | S | S | S | S |
| B | S | S |
| T | T | T |
| T | T |
|
| B |
| S |
Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
115 | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
. | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . |
  |
  |   |
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
. | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | A | T | P | D | E | L | A | P | F | A | K | A | D | . |
G | S | M | G | P | N | V | T | A | V | S | G | Y | V | R | S | R | G | K | P | A | W | I | G | A | L | S | R | I | E | E | T | L | A | G | E | A | G | T | C | I | S |
Query Conservation |   |
  |
|   |   |   |
|   |   |   |   |   |   |   |   | . |
|
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |
|   |   |
|
|   |
|   |   |
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |
|
|   |
|
|
|   |   |
|
|
|
|
|
|
|   | . | . | . |
|   |   |   |
|   |   |   |   |
|
|
|   |
|   |
|
| . | . | . | . | . | . |   |   |   |   |   |
|
|
|
|
|
Template Sequence |   |
E | I | T | C | D | E | M | L | E | L | A | S | L | G | A | K | V | L | H | P | R | . |
. |
. |
A | V | E | I | A | R | N | Y | G | I | P | L | V | V | R | S | S | . |
. |
. |
. |
. |
. |
W | S | D | E | P | G | T | K | V | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | G | G | G | G | T | T | T |
|
|  |  | . | . | . |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  | T | . | . | . | . | . | . | T |
|
|
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
196 | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | |
|
|
. | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 240 | . | . | . |
  |