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Job DescriptionP38104
Confidence89.23%DateThu Jan 5 11:57:58 GMT 2012
Rank227Aligned Residues164
% Identity13%Templatec2fptA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   115....120... ......130.........140.........150.........160.........170.........180.........
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Query Sequence  EGVMVYCHT. . . . . TGHSIDEALDDYARHQELGFKAIRVQCGIPGMKTTYGMSKGKGLAYEPATKGQWPEEQLWSTEKYL
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Template Sequence  DGLPLGVNLGKNKTSVDAAEDYAEGVRVLGP. LADYLVVNVSSPNTAGLRSLQGKA. . . . . . . . . . . . . . . . . . . . . . EL
Template Known Secondary structure  TT




TT
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TTSTTSGGGGS......................
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   174.....180.........190.........200.... .....210.........220........ .230
 
   190.........200..... ....210.........220.........230........ .240..
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Query Sequence  DFMPKLFDAVRNKFGF. . NEHLLHDMHHRLTPIEAARFGKSIEDYRMFWME. . . . . . . . . . . . . . . . . . . . . . . . . DPTP
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Template Sequence  RRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLR
Template Known Secondary structure  TS
GGG


S


T




BS


TT


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   231........240.........250.........260.........270.........280.........290.........300.........310
 
   243......250....... ..260.........270.........280.........290. ........300..
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Query Sequence  AENQECFRLIRQHTV. . TPIAVGEVFNSIWDCKQLIEEQLIDYIRTTLTHA. GGITGMRRIAD
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Template Sequence  DLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAG. ASLVQLYTALTFWGPPVVGKVKR
Template Known Secondary structure  TTT
S
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   311........320.........330.........340......... 350.........360.........370..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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