Job Description P76123 Confidence 99.94% Date Thu Jan 5 12:19:16 GMT 2012 Rank 19 Aligned Residues 303 % Identity 16% Template c2z81A_ PDB info PDB header:immune system Chain: A: PDB Molecule:toll-like receptor 2, variable lymphocyte receptor b; PDBTitle: crystal structure of the tlr1-tlr2 heterodimer induced by binding of a2 tri-acylated lipopeptide Resolution 1.80 Å

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.				.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.		.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.
Predicted Secondary structure																												.	.	.																						.
Query SS confidence																												.	.	.																						.
Query Sequence		I	T	D	L	I	L	H	N	H	P	R	M	K	T	I	T	L	N	D	N	H	I	A	H	L	N	.	.	.	A	K	N	T	T	K	L	E	Y	L	N	L	S	N	N	N	L	L	P	T	N	.	D	I	D	Q	L	I	S	S	K	H	L	W	H	V	L	V	N	G	I	N	N	D	P	L	A	Q	M	Q	Y
Query Conservation																												.	.	.																						.
Alig confidence																												.	.	.																						.
Template Conservation
Template Sequence		I	G	H	G	D	L	R	A	C	A	N	L	Q	V	L	I	L	K	S	S	R	I	N	T	I	E	G	D	A	F	Y	S	L	G	S	L	E	H	L	D	L	S	D	N	H	L	S	S	L	S	S	S	W	F	G	P	L	S	S	L	K	Y	L	N	L	M	G	N	P	Y	Q	T	L	G	V	T	S	L	F	P
Template Known Secondary structure				S	S	T	T	S	S		T	T							T	T	S							T	T	T	T	T	T		T	T							T	T	S				S							T	T		T	T							T	T				S	S	S		S	S		S		T
Template Predicted Secondary structure
Template SS confidence
		67	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.
		78	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	T	A	V	R	N	I	I	D	D	T	N	E	V	T	I	D	L	S	G	L	N	L	T	T	Q	P	P	G	L	Q	N	F	T	S	I	N	L	D	N	N	Q	F	T	H	F	D	A	T	N	Y	D	R	L	V	K	L	S	L	N	S	N	A	L	E	S	I	N	F	P	Q	G	R	N	V	S	I	T	H	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	L	T	N	L	Q	T	L	R	I	G	N	V	E	T	F	S	E	I	R	R	I	D	F	A	G	L	T	S	L	N	E	L	E	I	K	A	L	S	L	R	N	Y	Q	S	Q	S	L	K	S	I	R	D	I	H	H	L	T	L	H	L	S	E	S	A	F	L	L	E	I	F	A	D	I	L	S	S	V	R	Y
Template Known Secondary structure		T		T	T									S	S	S						T	T	T	T	T	T												T	T						T	T	T	T	T	T		S										S	B	S	T	T								S	T	T	T	B	S
Template Predicted Secondary structure
Template SS confidence
		147	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.
		158	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.
Predicted Secondary structure																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		S	M	N	N	N	A	L	R	N	I	D	I	D	R	L	S	S	V	T	Y	F	S	A	A	H	N	Q	L	E	F	V	Q	L	E	S	C	E	W	L	Q	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		L	E	L	R	D	T	N	L	A	R	F	Q	F	S	P	L	P	V	D	E	V	S	S	P	M	K	K	L	A	F	R	G	S	V	L	T	D	E	S	F	N	E	L	L	K	L	L	R	Y	I	L	E	L	S	E	V	E	F	D	D	C	T	L	N	G	L	G	D	F	N	P	S	E	S	D	V	V	S	E	L
Template Known Secondary structure						S		B		T	T							S	S														S													G	G	G	G	G		T	T								S							S						T	T	T
Template Predicted Secondary structure
Template SS confidence
		227	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		G	K	V	E	T	V	T	I	R	R	L	H	I	P	Q	F	Y	L	F	Y	D	L	S	T	V	Y	S	L	L	E	K	V	K	R	I	T	V	E	N	S	K	V	F	L	V	P	C	S	F	S	Q	H	L	K	S	L	E	F	L	D	L	S	E	N	L	M	V	E	E	Y	L	K	N	S	A	C	K	G	A	W
Template Known Secondary structure		T	T								S		B		S		G	G	G	S										S	T	T								S	S														T	T								S	S											T		T	T	S	S
Template Predicted Secondary structure
Template SS confidence
		307	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
																																			199	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	N	L	S	H	N	Q	L	T	D	I	V	A	G	N	K	N	E	L	L	L	L	D	L	S	H	N	K	L	T	S	L	H	N	D	L	F	P	N	L	N	T	L	L	I	N	N
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		P	S	L	Q	T	L	V	L	S	Q	N	H	L	R	S	M	Q	K	T	G	E	I	L	L	T	L	K	N	L	T	S	L	D	I	S	R	N	T	F	H	P	M	P	D	S	C	Q	W	P	E	K	M	R	F	L	N	L	S	S	T	G	I	R	V	V	K	T	C	I	P	Q	T	L	E	V	L	D	V	S	N
Template Known Secondary structure		T	T							T	T	S												G	G	G		T	T							T	T								S						T	T							T	T	S			S				T	T	S		T	T		S						S
Template Predicted Secondary structure
Template SS confidence
		387	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.
		246	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	L	L	S	E	I	K	I	F	Y	S	N	F	C	N	V	Q	T	L	N	A	A	N	N	Q	L	K	Y	I	N	L	D	F	L	T	Y	L	P	S	I	K	S	L	R	L	D	N	N	K	I	T	H	I	D	T	N	N	T	S	D	I	G	T	L
Query Conservation
Alig confidence										.	.	.																								.	.
Template Conservation										.	.	.																								.	.
Template Sequence		N	N	L	D	S	F	S	L	.	.	.	F	L	P	R	L	Q	E	L	Y	I	S	R	N	K	L	K	T	L	P	D	A	S	L	.	.	F	P	V	L	L	V	M	K	I	S	R	N	Q	L	K	S	V	P	D	G	I	F	D	R	L	T	S	L
Template Known Secondary structure		S			S					.	.	.			T	T								S	S			S	S				G	G	G	.	.		T	T								S	S							T	T	G	G	G	G		T	T
Template Predicted Secondary structure										.	.	.																								.	.
Template SS confidence
		467	.	.	470	.	.	.	.				.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.			.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.