Return to main results Retrieve Phyre Job Id

Job DescriptionP76123
Confidence99.95%DateThu Jan 5 12:19:16 GMT 2012
Rank9Aligned Residues308
% Identity16%Templatec2z64A_
PDB info PDB header:immune systemChain: A: PDB Molecule:toll-like receptor 4; PDBTitle: crystal structure of mouse tlr4 and mouse md-2 complex
Resolution2.84 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20....... ..30.........40....... ..50.........60.........70.......
Predicted Secondary structure 


















...













.





























Query SS confidence 

























. . .



















.





























Query Sequence  ITDLILHNHPRMKTITLNDNHIAHLN. . . AKNTTKLEYLNLSNNNLLPT. NDIDQLISSKHLWHVLVNGINNDPLAQMQY
Query Conservation 

   
  
  
  
 

 
 
  
 ...   
  
  
 

 
 
  
.         
  
 
  
            
Alig confidence 

























...



















.





























Template Conservation 
    
  
  
  
 

 
 
  
    
  
  
  
 

 
 
  
    
  
  
  
 
  
 
  
       
Template Sequence  LKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQ
Template Known Secondary structure 
TTTTSS
TT


SS




TTTTTT
TT


TT






TTTTTT
TT


TTS



TTT


TT
Template Predicted Secondary structure 





















































Template SS confidence 















































































   68.70.........80.........90.........100.........110.........120.........130.........140.......
 
   78.80.........90.........100.........110.........120...
Predicted Secondary structure 













































..................................
Query SS confidence 













































. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  WTAVRNIIDDTNEVTIDLSGLNLTTQPPGLQNFTSINLDNNQFTHF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation                                                ..................................
Alig confidence 













































..................................
Template Conservation 
  
  
 
  
                
  
    
                                           
Template Sequence  LITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKL
Template Known Secondary structure 
TT



SS







GGGGT
TT


TTS



TTTTTTTTT
TT



TT




TTTTTT
Template Predicted Secondary structure 












































































Template SS confidence 















































































   148.150.........160.........170.........180.........190.........200.........210.........220.......
 
  
Predicted Secondary structure  ................................................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                                                                                  
Template Sequence  HELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLAN
Template Known Secondary structure  S

SST
S

TTSS

S


GGGGTTTTTS


SS

TTGGG
GGGTT
Template Predicted Secondary structure 








































































Template SS confidence 















































































   228.230.........240.........250.........260.........270.........280.........290.........300.......
 
   124.....
Predicted Secondary structure  ..........................................................................





Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .





Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DATNYD
Query Conservation  ..........................................................................      
Alig confidence  ..........................................................................





Template Conservation 
                                                                   
           
Template Sequence  VSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSG
Template Known Secondary structure 
SS









TT


SS


SS





TT

SBSS

B





TT



SBS
B
Template Predicted Secondary structure 















































































Template SS confidence 















































































   308.310.........320.........330.........340.........350.........360.........370.........380.......
 
   130.........140.........150.........160.........170.........180.........190.........200.........
Predicted Secondary structure 















































































Query SS confidence 















































































Query Sequence  RLVKLSLNSNALESINFPQGRNVSITHISMNNNALRNIDIDRLSSVTYFSAAHNQLEFVQLESCEWLQYLNLSHNQLTDI
Query Conservation                                                                                  
Alig confidence 















































































Template Conservation                                    
                        
                    
Template Sequence  CCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLG
Template Known Secondary structure 
SS
S




S
S
S

TT
TT


TTSSTTTS
TTTT
TT


TTS



S
TTTT
Template Predicted Secondary structure 











































































Template SS confidence 















































































   388.390.........400.........410.........420.........430.........440.........450.........460.......
 
   210.........220.........230.........240.........250.... .....260.........270.........280........
Predicted Secondary structure 












































.
























Query SS confidence 












































.

































Query Sequence  VAGNKNELLLLDLSHNKLTSLHNDLFPNLNTLLINNNLLSEIKIF. YSNFCNVQTLNAANNQLKYINLDFLTYLPSIKSL
Query Conservation                                   
  
        .   
  
  
 

 
 
  
    
  
  
  
Alig confidence 












































.

































Template Conservation     
  
 
  
                
  
 

 
 
  
    
  
  
  
 

 
 
  
    
  
  
  
Template Sequence  LTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTL
Template Known Secondary structure 
TT


TT
GGG
STTSS
TT
S
TT




TTTTTT
TT



SS


GGGTTT
TT

Template Predicted Secondary structure 































































Template SS confidence 















































































   468.470.........480.........490.........500.........510.........520.........530.........540.......
 
   289290.........300.........
Predicted Secondary structure 














Query SS confidence 




















Query Sequence  RLDNNKITHIDTNNTSDIGTL
Query Conservation   

 
 
  
    
  
  
Alig confidence 




















Template Conservation   

 
 
             
Template Sequence  DCSFNRIETSKGILQHFPKSL
Template Known Secondary structure 

SS


S
GGGS
TT
Template Predicted Secondary structure 














Template SS confidence 




















   548.550.........560........
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions