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Job DescriptionP76123
Confidence99.94%DateThu Jan 5 12:19:16 GMT 2012
Rank15Aligned Residues308
% Identity18%Templatec2a0zA_
PDB info PDB header:immune systemChain: A: PDB Molecule:toll-like receptor 3; PDBTitle: the molecular structure of toll-like receptor 3 ligand binding domain
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20....... ..30.........40....... ..50.........60.........70.......
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Query Sequence  ITDLILHNHPRMKTITLNDNHIAHLN. . . AKNTTKLEYLNLSNNNLLPT. NDIDQLISSKHLWHVLVNGINNDPLAQMQY
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Template Conservation 
    
  
  
  
 

 
 
  
    
  
  
  
 

 
 
  
    
  
  
  
 

 
 
          
Template Sequence  LPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK
Template Known Secondary structure 

GGGGTT
TT
S

SS





TT
TT



SS





TTTTTT
TT
S
TTS





S
TTTT
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   66...70.........80.........90.........100.........110.........120.........130.........140.....
 
   78.80.........90.........100.........110.........120...
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Query Sequence  WTAVRNIIDDTNEVTIDLSGLNLTTQPPGLQNFTSINLDNNQFTHF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG
Template Known Secondary structure 
TT



SS







SSS

TT



SS



B
GGGTGGGTT
S

S




B
TTTTTTSS
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   146...150.........160.........170.........180.........190.........200.........210.........220.....
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                                                                                 
Template Sequence  LFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFL
Template Known Secondary structure 
TT



TTTS



TTS



TTTTGGGGGS



TTS



TTTTTT
TT


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   226...230.........240.........250.........260.........270.........280.........290.........300.....
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                                                                                  
Template Sequence  EYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS
Template Known Secondary structure 
S

B

TTTTTT
TT


TT
B



SSS




TTTTTT
TT



S

B



TTSSTT
TT

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   306...310.........320.........330.........340.........350.........360.........370.........380.....
 
   124.....130.........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DATNYDRLVKLSLNSN
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Template Conservation                                                                                  
Template Sequence  LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSY
Template Known Secondary structure 
TT
BS



SSTTGGGTTS




SS



TTTTTT
TT



SS



SGGGTT
TT



S
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   386...390.........400.........410.........420.........430.........440.........450.........460.....
 
   140.........150.........160.........170.........180.........190.........200.........210.........
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Query Sequence  ALESINFPQGRNVSITHISMNNNALRNIDIDRLSSVTYFSAAHNQLEFVQLESCEWLQYLNLSHNQLTDIVAGNKNELLL
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Template Conservation                                            
                       
       
 
  
Template Sequence  NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL
Template Known Secondary structure 
S

TTTTTT
TT



SS

B
TT
SS
TTTT
TT



SS





TTTTTT
TT



SS

GGG
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   466...470.........480.........490.........500.........510.........520.........530.........540.....
 
   220.........230.........240.........250.... .....260.........270.........280.........290........
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Query Sequence  LDLSHNKLTSLHNDLFPNLNTLLINNNLLSEIKIF. YSNFCNVQTLNAANNQLKYINLDFLTYLPSIKSLRLDNNKITHI
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Template Conservation                 
  
  
 

 
 
  
    
  
  
  
 

 
 
       
  
  
  
 

 
 
  
Template Sequence  WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV
Template Known Secondary structure  GSTTSTT



TTTT
TT



SS





TTTTTT
TT



SS





TTTTTT
TT


TTS




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   546...550.........560.........570.........580.........590.........600.........610.........620.....
 
   299300..... ....
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Query Sequence  DTNNTSD. IGTL
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Template Conservation          
  
Template Sequence  EKKVFGPAFRNL
Template Known Secondary structure 
TT
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   626...630.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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