|   |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | |
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
F | R | S | G | A | E | S | L | P | D | A | V | V | L | T | T | E | E | G | G | I | F | W | C | N | G | L | A | Q | Q | I | L | G | L | R | W | P | E | D | N | G | Q | N | I | L | N | L | L | R | Y | P | E | F | T | Q | Y | L | K | T | R | D | F | S | R | P | L | N | L | V | L | N | T | G | . |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |
|   |
|   |   |   |   |
|
|   |
|   |
|   |   |
|   |
|   |   |   |
|   |
|   |   |   |
|   |
|   |   |   |
|
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | E | S | I | L | E | S | L | E | T | A | I | I | T | L | S | K | D | G | R | I | T | E | W | N | K | K | A | E | Q | L | F | G | L | K | K | E | N | V | L | G | R | R | L | K | D | L | P | D | F | E | E | I | G | S | V | A | E | S | V | F | E | N | K | E | P | V | F | L | N | F | Y | K | F | G | E | R | Y | F | N |
Template Known Secondary structure |   |
|
| S | S | G | G | G | S | S | S |  |  |  |  |  |  | S | S | S | B |
| S |
| B |
|  |  |  |  |  |  |  | S |
|
| S | T | T | T | T | T |
| B | S | T | T | S | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
| B | T | T | B |
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
416 | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . |
  |
  |   |
|
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
. |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
R | H | L | E | I | R | V | M | P | Y | T | H | K | Q | L | L | M | V | A | R | D | V | T | Q | M | H | Q | L | E | G | A | R | R | N | F | F | A | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | S | H | E | L | R | T | P | L | T | V | L | Q | G | Y | L | E | M | M | N | E | Q | P | L | E | G | A | V | R | E | K |
Query Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | R | F | S | P | F | R | N | A | K | T | Q | L | L | E | G | V | I | I | T | I | D | D | V | T | E | L | Y | K | Y | E | E | E | R | K | R | R | E | R | L | S | I | L | G | E | M | T | A | R | V | A | H | E | I | R | N | P | I | T | I | I | G | G | F | I | M | R | M | K | K | H | L | D | D | P | E | T | L | K | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
| T | T | T | T | S | S |
|  |  |  |  |  |  |  |
|
| S | T | T | T | T | T | T | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S |
| S | S |
| T | T |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
496 | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . |
  |
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | H | T | M | R | E | Q | T | Q | R | M | E | G | L | V | K | Q | L | L | T | L | S | K | I | E | A | A | P | T | H | L | L | N | E | K | V | D | V | P | M | M | L | R | V | V | E | R | E | A | Q | T | L | S | Q | K | K | Q | T | F | T | F | E | I | D | N | G | L | K | V | S | G | N | E | D | Q | L | R | S | A |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | I | N | I | I | T | N | E | L | S | R | L | E | T | I | V | K | E | I | L | E | Y | S | K | E | R | V | L | E | F | T | E | F | N | L | N | E | L | I | R | E | V | Y | V | L | F | E | E | K | I | R | K | . |
. |
M | N | I | D | F | C | F | E | T | D | N | E | D | L | R | V | E | A | D | R | T | R | I | K | Q | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | T | T |
|
|
|  |  |  |  | S |
| S |
|
|  |  |  |  |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
576 | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | |
|
. | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . |
  |
  |   |
322 | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | |
400 |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Query Sequence |   |
I | S | N | L | V | Y | N | A | V | N | H | T | P | E | G | T | H | I | T | V | R | W | Q | R | V | P | H | G | A | E | F | S | V | E | D | N | G | P | G | I | A | P | E | H | I | P | R | L | T | E | R | F | Y | R | V | D | K | A | R | S | R | Q | T | G | G | S | G | L | G | L | A | I | V | K | H | A | V | N | . |
H |
Query Conservation |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|
|   |
|
|   |   |
|   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|
|
|   |
|   |   |   |
|
|   | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Template Conservation |   |
  |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|
|
|
|
|   | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|   |
|
|   |   |
|
|   |   |   |
Template Sequence |   |
L | I | N | L | V | Q | N | A | I | E | A | T | G | E | N | G | K | I | K | I | T | S | E | D | M | Y | T | K | V | R | V | S | V | W | N | S | G | P | P | I | P | E | E | L | K | E | K | I | F | S | P | F | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | T | L | G | L | S | I | C | R | K | I | I | E | D | E |
Template Known Secondary structure |   |
 |  |  |  |  | T |  |  |  |  | T | T |
| T | T |
|
|  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | S |
|
|
|
| G | G | G | G | T | T | T | S | S | S |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| T |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
655 | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . |
  |
  |   |
401 | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | E | S | R | L | N | I | E | S | T | V | G | K | G | T | R | F | S | F | V | I | P | E |
Query Conservation |   |
  |
|
|   |
|   |
|   |
|   |   |
|   |
|
|   |
|   |
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|   |
|   |
|   | . |   |   |
|
|   |
|   |
|   |
|
|   |
Template Sequence |   |
H | G | G | K | I | W | T | E | N | R | . |
E | N | G | V | V | F | I | F | E | I | P | K |
Template Known Secondary structure |   |
T |
| S | B |
|
|  |  |  |
| . | S | S |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
729 | 730 | . | . | . | . | . | . | . | . | |
. | 740 | . | . | . | . | . | . | . | . | . | 750 |
  |