Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	S	T	H	H	Y	E	Q	L	I	E	I	F	N	S	C	F	A	D	D	F	N	T	R	L	I	K	G	D	D	E	P	I	Y	L	P	A	D	A	E	V	P	Y	N	R	I	V	F	A	H	G	F	Y	A	S	A	I	H	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	S	H	W	C	I	A	G	K	A	R	R	E	L	V	D	F	G	Y	W	Y	C	P	D	G	R	D	A	Q	T	Q	S	Q	F	E	D	V	E	V	K	P	Q	A	L	D	W	L	F	C	V	A	A	G	Y	P	F	N	V	S	C
Secondary structure
SS confidence
Disorder																												?										?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	N	L	E	G	D	F	E	P	D	R	V	V	F	Q	R	R	V	H	A	Q	V	M	D	Y	L	T	N	G	I	P	E	R	P	A	R	F	I	K	A	L	Q	N	Y	Y	H	T	P	E	L	T	A	E	Q	F	P	W	P	E	A
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?	?	?																																								?					?	?	?	?	?
Disorder confidence
		.	.
Sequence		L	N
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3hft chain A Region: 72 - 85 Aligned: 14 Modelled: 14 Confidence: 50.8% Identity: 50% PDB header:hydrolase Chain: A: PDB Molecule:wbms, polysaccharide deacetylase involved in o-antigen PDBTitle: crystal structure of a putative polysaccharide deacetylase involved in2 o-antigen biosynthesis (wbms, bb0128) from bordetella bronchiseptica3 at 1.90 a resolution Phyre2 PDB 1h3i chain A domain 2 Region: 73 - 86 Aligned: 14 Modelled: 14 Confidence: 47.5% Identity: 36% Fold: beta-clip Superfamily: SET domain Family: Histone lysine methyltransferases Phyre2 PDB 3pmi chain C Region: 98 - 127 Aligned: 30 Modelled: 30 Confidence: 42.9% Identity: 23% PDB header:protein binding Chain: C: PDB Molecule:pwwp domain-containing protein mum1; PDBTitle: pwwp domain of human mutated melanoma-associated antigen 1 Phyre2 PDB 1g12 chain A Region: 58 - 79 Aligned: 17 Modelled: 22 Confidence: 32.0% Identity: 41% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Fungal zinc peptidase Phyre2 PDB 1su3 chain A Region: 52 - 63 Aligned: 12 Modelled: 12 Confidence: 28.3% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:interstitial collagenase; PDBTitle: x-ray structure of human prommp-1: new insights into2 collagenase action Phyre2 PDB 3csk chain A Region: 2 - 64 Aligned: 62 Modelled: 63 Confidence: 26.4% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:probable dipeptidyl-peptidase 3; PDBTitle: structure of dpp iii from saccharomyces cerevisiae Phyre2 PDB 2pu9 chain A domain 1 Region: 72 - 84 Aligned: 13 Modelled: 13 Confidence: 23.1% Identity: 31% Fold: Ferredoxin thioredoxin reductase (FTR), catalytic beta chain Superfamily: Ferredoxin thioredoxin reductase (FTR), catalytic beta chain Family: Ferredoxin thioredoxin reductase (FTR), catalytic beta chain Phyre2 PDB 1ycd chain A Region: 46 - 86 Aligned: 38 Modelled: 41 Confidence: 22.4% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical 27.3 kda protein in aap1-smf2 PDBTitle: crystal structure of yeast fsh1/yhr049w, a member of the2 serine hydrolase family Phyre2 PDB 1lml chain A Region: 53 - 63 Aligned: 11 Modelled: 11 Confidence: 21.4% Identity: 27% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Leishmanolysin Phyre2 PDB 1om8 chain A Region: 53 - 63 Aligned: 11 Modelled: 11 Confidence: 20.6% Identity: 36% PDB header:hydrolase Chain: A: PDB Molecule:serralysin; PDBTitle: crystal structure of a cold adapted alkaline protease from pseudomonas2 tac ii 18, co-crystallyzed with 10 mm edta Phyre2 PDB 1xuc chain A domain 1 Region: 52 - 63 Aligned: 12 Modelled: 12 Confidence: 19.4% Identity: 33% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 3mc4 chain A Region: 37 - 65 Aligned: 28 Modelled: 29 Confidence: 19.3% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:ww/rsp5/wwp domain:bacterial transferase PDBTitle: crystal structure of ww/rsp5/wwp domain: bacterial2 transferase hexapeptide repeat: serine o-acetyltransferase3 from brucella melitensis Phyre2 PDB 2j83 chain B Region: 55 - 64 Aligned: 10 Modelled: 10 Confidence: 18.6% Identity: 60% PDB header:hydrolase Chain: B: PDB Molecule:ulilysin; PDBTitle: ulilysin metalloprotease in complex with batimastat. Phyre2 PDB 3c18 chain B Region: 60 - 72 Aligned: 13 Modelled: 13 Confidence: 18.2% Identity: 38% PDB header:transferase Chain: B: PDB Molecule:nucleotidyltransferase-like protein; PDBTitle: crystal structure of nucleotidyltransferase-like protein2 (zp_00538802.1) from exiguobacterium sibiricum 255-15 at 1.90 a3 resolution Phyre2 PDB 1sat chain A domain 2 Region: 54 - 63 Aligned: 10 Modelled: 10 Confidence: 17.7% Identity: 40% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Serralysin-like metalloprotease, catalytic (N-terminal) domain Phyre2 PDB 1i76 chain A Region: 51 - 63 Aligned: 13 Modelled: 13 Confidence: 17.5% Identity: 31% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 PDB 1slm chain A Region: 52 - 63 Aligned: 12 Modelled: 12 Confidence: 17.3% Identity: 42% PDB header:hydrolase Chain: A: PDB Molecule:stromelysin-1; PDBTitle: crystal structure of fibroblast stromelysin-1: the c-truncated human2 proenzyme Phyre2 PDB 3cqb chain B Region: 59 - 64 Aligned: 6 Modelled: 6 Confidence: 17.2% Identity: 67% PDB header:hydrolase Chain: B: PDB Molecule:probable protease htpx homolog; PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633 Phyre2 PDB 1dxx chain A domain 2 Region: 95 - 178 Aligned: 82 Modelled: 84 Confidence: 17.0% Identity: 15% Fold: CH domain-like Superfamily: Calponin-homology domain, CH-domain Family: Calponin-homology domain, CH-domain Phyre2 PDB 1cxv chain A Region: 52 - 63 Aligned: 12 Modelled: 12 Confidence: 16.9% Identity: 33% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Matrix metalloproteases, catalytic domain Phyre2 1 c3hftA_ 2 d1h3ia2 3 c3pmiC_ 4 d1g12a_ 5 c1su3A_ 6 c3cskA_ 7 d2pu9a1 8 c1ycdA_ 9 d1lmla_ 10 c1om8A_ 11 d1xuca1 12 c3mc4A_ 13 c2j83B_ 14 c3c18B_ 15 d1sata2 16 d1i76a_ 17 c1slmA_ 18 c3cqbB_ 19 d1dxxa2 20 d1cxva_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3hftA_ 50.8 50 PDB header:hydrolase Chain: A: PDB Molecule:wbms, polysaccharide deacetylase involved in o-antigen PDBTitle: crystal structure of a putative polysaccharide deacetylase involved in2 o-antigen biosynthesis (wbms, bb0128) from bordetella bronchiseptica3 at 1.90 a resolution 2 d1h3ia2 47.5 36 Fold:beta-clip Superfamily:SET domain Family:Histone lysine methyltransferases 3 c3pmiC_ 42.9 23 PDB header:protein binding Chain: C: PDB Molecule:pwwp domain-containing protein mum1; PDBTitle: pwwp domain of human mutated melanoma-associated antigen 1 4 d1g12a_ 32.0 41 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Fungal zinc peptidase 5 c1su3A_ 28.3 33 PDB header:hydrolase Chain: A: PDB Molecule:interstitial collagenase; PDBTitle: x-ray structure of human prommp-1: new insights into2 collagenase action 6 c3cskA_ 26.4 19 PDB header:hydrolase Chain: A: PDB Molecule:probable dipeptidyl-peptidase 3; PDBTitle: structure of dpp iii from saccharomyces cerevisiae 7 d2pu9a1 23.1 31 Fold:Ferredoxin thioredoxin reductase (FTR), catalytic beta chain Superfamily:Ferredoxin thioredoxin reductase (FTR), catalytic beta chain Family:Ferredoxin thioredoxin reductase (FTR), catalytic beta chain 8 c1ycdA_ 22.4 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical 27.3 kda protein in aap1-smf2 PDBTitle: crystal structure of yeast fsh1/yhr049w, a member of the2 serine hydrolase family 9 d1lmla_ 21.4 27 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Leishmanolysin 10 c1om8A_ 20.6 36 PDB header:hydrolase Chain: A: PDB Molecule:serralysin; PDBTitle: crystal structure of a cold adapted alkaline protease from pseudomonas2 tac ii 18, co-crystallyzed with 10 mm edta 11 d1xuca1 19.4 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 12 c3mc4A_ 19.3 29 PDB header:transferase Chain: A: PDB Molecule:ww/rsp5/wwp domain:bacterial transferase PDBTitle: crystal structure of ww/rsp5/wwp domain: bacterial2 transferase hexapeptide repeat: serine o-acetyltransferase3 from brucella melitensis 13 c2j83B_ 18.6 60 PDB header:hydrolase Chain: B: PDB Molecule:ulilysin; PDBTitle: ulilysin metalloprotease in complex with batimastat. 14 c3c18B_ 18.2 38 PDB header:transferase Chain: B: PDB Molecule:nucleotidyltransferase-like protein; PDBTitle: crystal structure of nucleotidyltransferase-like protein2 (zp_00538802.1) from exiguobacterium sibiricum 255-15 at 1.90 a3 resolution 15 d1sata2 17.7 40 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 16 d1i76a_ 17.5 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 17 c1slmA_ 17.3 42 PDB header:hydrolase Chain: A: PDB Molecule:stromelysin-1; PDBTitle: crystal structure of fibroblast stromelysin-1: the c-truncated human2 proenzyme 18 c3cqbB_ 17.2 67 PDB header:hydrolase Chain: B: PDB Molecule:probable protease htpx homolog; PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633 19 d1dxxa2 17.0 15 Fold:CH domain-like Superfamily:Calponin-homology domain, CH-domain Family:Calponin-homology domain, CH-domain 20 d1cxva_ 16.9 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 21 d1tqha_ not modelled 16.8 27 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/lipase 22 c2x3bB_ not modelled 16.7 35 PDB header:hydrolase Chain: B: PDB Molecule:toxic extracellular endopeptidase; PDBTitle: asap1 inactive mutant e294a, an extracellular toxic zinc2 metalloendopeptidase 23 c3dtkA_ not modelled 16.6 38 PDB header:gene regulation Chain: A: PDB Molecule:irre protein; PDBTitle: crystal structure of the irre protein, a central regulator2 of dna damage repair in deinococcaceae 24 d1cgla_ not modelled 16.2 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 25 d1q3aa_ not modelled 16.2 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 26 d1hova_ not modelled 16.2 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 27 d1k7ia2 not modelled 16.2 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 28 d1g9ka2 not modelled 16.2 40 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 29 d1eaka2 not modelled 16.1 25 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 30 d1poca_ not modelled 15.9 24 Fold:Phospholipase A2, PLA2 Superfamily:Phospholipase A2, PLA2 Family:Insect phospholipase A2 31 c2jsdA_ not modelled 15.5 33 PDB header:hydrolase Chain: A: PDB Molecule:matrix metalloproteinase-20; PDBTitle: solution structure of mmp20 complexed with nngh 32 d1hfca_ not modelled 15.2 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 33 d1rm8a_ not modelled 15.1 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 34 d1kapp2 not modelled 14.9 40 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 35 d1bqqm_ not modelled 14.7 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 36 c3ls2D_ not modelled 14.6 12 PDB header:hydrolase Chain: D: PDB Molecule:s-formylglutathione hydrolase; PDBTitle: crystal structure of an s-formylglutathione hydrolase from2 pseudoalteromonas haloplanktis tac125 37 c1zmhA_ not modelled 14.3 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 2; PDBTitle: crystal structure of human neutrophil peptide 2, hnp-2 (variant gly16-2 > d-ala) 38 c1zmhD_ not modelled 14.3 71 PDB header:antimicrobial protein Chain: D: PDB Molecule:neutrophil defensin 2; PDBTitle: crystal structure of human neutrophil peptide 2, hnp-2 (variant gly16-2 > d-ala) 39 c1zmkA_ not modelled 14.3 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 2; PDBTitle: crystal structure of human alpha-defensin-2 (variant gly16-> d-ala), p2 42 21 2 space group 40 c1zmiC_ not modelled 14.3 71 PDB header:antimicrobial protein Chain: C: PDB Molecule:neutrophil defensin 2; PDBTitle: crystal structure of human alpha_defensin-2 (variant gly16->d-ala), p2 32 2 1 space group ) 41 c1zmiA_ not modelled 14.3 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 2; PDBTitle: crystal structure of human alpha_defensin-2 (variant gly16->d-ala), p2 32 2 1 space group ) 42 c1zmkB_ not modelled 14.3 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:neutrophil defensin 2; PDBTitle: crystal structure of human alpha-defensin-2 (variant gly16-> d-ala), p2 42 21 2 space group 43 c1zmhC_ not modelled 14.3 71 PDB header:antimicrobial protein Chain: C: PDB Molecule:neutrophil defensin 2; PDBTitle: crystal structure of human neutrophil peptide 2, hnp-2 (variant gly16-2 > d-ala) 44 c1zmiB_ not modelled 14.3 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:neutrophil defensin 2; PDBTitle: crystal structure of human alpha_defensin-2 (variant gly16->d-ala), p2 32 2 1 space group ) 45 c1zmhB_ not modelled 14.3 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:neutrophil defensin 2; PDBTitle: crystal structure of human neutrophil peptide 2, hnp-2 (variant gly16-2 > d-ala) 46 c1zmiD_ not modelled 14.3 71 PDB header:antimicrobial protein Chain: D: PDB Molecule:neutrophil defensin 2; PDBTitle: crystal structure of human alpha_defensin-2 (variant gly16->d-ala), p2 32 2 1 space group ) 47 d1fbla2 not modelled 14.1 42 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 48 d1y93a1 not modelled 14.0 42 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 49 c3ba0A_ not modelled 13.9 42 PDB header:hydrolase Chain: A: PDB Molecule:macrophage metalloelastase; PDBTitle: crystal structure of full-length human mmp-12 50 c3fcxA_ not modelled 13.8 14 PDB header:hydrolase Chain: A: PDB Molecule:s-formylglutathione hydrolase; PDBTitle: crystal structure of human esterase d 51 c2wtmC_ not modelled 13.6 17 PDB header:hydrolase Chain: C: PDB Molecule:est1e; PDBTitle: est1e from butyrivibrio proteoclasticus 52 d2hu7a1 not modelled 13.5 20 Fold:7-bladed beta-propeller Superfamily:Peptidase/esterase 'gauge' domain Family:Acylamino-acid-releasing enzyme, N-terminal donain 53 c3hjdB_ not modelled 13.5 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:human neutrophil peptide 1; PDBTitle: x-ray structure of monomeric variant of hnp1 54 c3hjdA_ not modelled 13.5 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:human neutrophil peptide 1; PDBTitle: x-ray structure of monomeric variant of hnp1 55 c2xs4A_ not modelled 13.4 42 PDB header:hydrolase Chain: A: PDB Molecule:karilysin protease; PDBTitle: structure of karilysin catalytic mmp domain in complex with2 magnesium 56 c2cltB_ not modelled 13.4 25 PDB header:hydrolase Chain: B: PDB Molecule:interstitial collagenase; PDBTitle: crystal structure of the active form (full-length) of human2 fibroblast collagenase. 57 d1mmqa_ not modelled 13.3 36 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 58 c3lo4B_ not modelled 13.3 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (r24a mutant) 59 c3lo4A_ not modelled 13.3 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (r24a mutant) 60 d1dfna_ not modelled 13.3 71 Fold:Defensin-like Superfamily:Defensin-like Family:Defensin 61 c3lvxA_ not modelled 13.2 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (i6a mutant) 62 c3lo6A_ not modelled 13.2 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (w26aba mutant) 63 c3lo9B_ not modelled 13.2 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (w26ahp mutant) 64 c3lo6B_ not modelled 13.2 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (w26aba mutant) 65 c3lo9A_ not modelled 13.2 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (w26ahp mutant) 66 c3lvxB_ not modelled 13.1 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (i6a mutant) 67 c3gnyB_ not modelled 13.1 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (hnp1) 68 c3h6cB_ not modelled 12.9 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (mutant gln22ala) 69 c3h6cA_ not modelled 12.9 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (mutant gln22ala) 70 c3lo2B_ not modelled 12.8 71 PDB header:antimicrobial protein Chain: B: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (y21a mutant) 71 c3lo2A_ not modelled 12.8 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (y21a mutant) 72 c3lo1A_ not modelled 12.8 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (y16a mutant) 73 c2zagB_ not modelled 12.8 80 PDB header:transferase Chain: B: PDB Molecule:oligosaccharyl transferase stt3 subunit related protein; PDBTitle: crystal structure of the semet-substituted soluble domain of stt3 from2 p. furiosus 74 c3noyA_ not modelled 12.7 14 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: crystal structure of ispg (gcpe) 75 d1vlta_ not modelled 12.7 27 Fold:Four-helical up-and-down bundle Superfamily:Aspartate receptor, ligand-binding domain Family:Aspartate receptor, ligand-binding domain 76 d1hy7a_ not modelled 12.4 42 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 77 d1xdna_ not modelled 12.3 15 Fold:ATP-grasp Superfamily:DNA ligase/mRNA capping enzyme, catalytic domain Family:RNA ligase 78 c1i8yA_ not modelled 12.2 56 PDB header:cytokine Chain: A: PDB Molecule:granulin-1; PDBTitle: semi-automatic structure determination of the cg1 3-302 peptide based on aria 79 d1i8ya_ not modelled 12.2 56 Fold:Knottins (small inhibitors, toxins, lectins) Superfamily:Granulin repeat Family:Granulin repeat 80 d1sr9a1 not modelled 11.9 32 Fold:RuvA C-terminal domain-like Superfamily:post-HMGL domain-like Family:DmpG/LeuA communication domain-like 81 d2ejqa1 not modelled 11.9 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TTHA0227-like 82 d2ovxa1 not modelled 11.8 25 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 83 c3o0lB_ not modelled 11.3 43 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a pfam duf1425 family member (shew_1734) from2 shewanella sp. pv-4 at 1.81 a resolution 84 d1m0wa1 not modelled 11.3 8 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Eukaryotic glutathione synthetase, substrate-binding domain 85 c3loeA_ not modelled 11.2 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (f28a mutant) 86 c3gnyA_ not modelled 11.0 71 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 1; PDBTitle: crystal structure of human alpha-defensin 1 (hnp1) 87 c1xqhE_ not modelled 11.0 29 PDB header:transferase Chain: E: PDB Molecule:histone-lysine n-methyltransferase, h3 lysine-4 PDBTitle: crystal structure of a ternary complex of the2 methyltransferase set9 (also known as set7/9) with a p533 peptide and sah 88 c2pm4A_ not modelled 10.9 57 PDB header:antimicrobial protein Chain: A: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1) (defensin, alpha PDBTitle: human alpha-defensin 1 (multiple arg->lys mutant) 89 d1hv5a_ not modelled 10.8 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 90 d1qiba_ not modelled 10.8 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 91 c2d99A_ not modelled 10.8 13 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i repeat domain- PDBTitle: solution structure of rsgi ruh-048, a gtf2i domain in human2 cdna 92 d1pv1a_ not modelled 10.7 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical esterase YJL068C 93 d1jwya1 not modelled 10.7 80 Fold:SH3-like barrel Superfamily:Myosin S1 fragment, N-terminal domain Family:Myosin S1 fragment, N-terminal domain 94 c3f67A_ not modelled 10.6 14 PDB header:hydrolase Chain: A: PDB Molecule:putative dienelactone hydrolase; PDBTitle: crystal structure of putative dienelactone hydrolase from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578 95 c2dzrA_ not modelled 10.5 35 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i repeat domain- PDBTitle: solution structure of rsgi ruh-067, a gtf2i domain in human2 cdna 96 c2hdwB_ not modelled 10.3 30 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protein pa2218; PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa 97 d1i0ua2 not modelled 10.2 20 Fold:Knottins (small inhibitors, toxins, lectins) Superfamily:EGF/Laminin Family:EGF-type module 98 d2crna1 not modelled 10.1 50 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:UBA domain 99 d3bz7a1 not modelled 10.0 80 Fold:SH3-like barrel Superfamily:Myosin S1 fragment, N-terminal domain Family:Myosin S1 fragment, N-terminal domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0